Delivering Compression to Treat Chronic Wounds in the UK & Ireland

2018 ◽  
pp. 39-63 ◽  
Author(s):  
Georgina Gethin ◽  
Andrew Ross Cameron
Keyword(s):  
Chronic Wounds ◽  
The Uk

scholarly journals Letters: Comment on Guest et al. ‘The health economic burden that acute and chronic wounds impose on an average clinical commissioning group/health board in the UK’ JWC June 2017; 26: 6.

2017 ◽  
Vol 26 (6) ◽  
pp. 353-355
Author(s):  
Richard White ◽  
Gary Smerdon ◽  
Alexandra Bishop ◽  
Sarah Witts ◽  
Jacqui Reeves ◽  
...  
Keyword(s):  
Health Economic ◽  
Economic Burden ◽  
Chronic Wounds ◽  
Health Board ◽  
Group Health ◽  
The Uk

Embedding National Institute for Health and Care Excellence guidance into a leg ulcer pathway

2019 ◽  
Vol 24 (Sup9) ◽  
pp. S6-S11
Author(s):  
Julie Mullings
Keyword(s):  
Chronic Wounds ◽  
Wound Care ◽  
Compression Therapy ◽  
Leg Ulcer ◽  
Evidence Based ◽  
Leg Ulcers ◽  
Correct Treatment ◽  
Treatment Choices ◽  
Venous Leg Ulcers ◽  
The Uk

Research has shown that leg ulcers represent the largest category of wound type treated within the UK. Venous leg ulcers are often classified as chronic wounds with increased protease levels causing the wound to become suspended in the inflammatory stage, which leads to delayed healing. If treatment choices are not evidence-based and appropriate regimens are not instigated early on in the wound care journey, the cost to both the patient and the healthcare service is substantial. Recent guidance from the National Institute of Health and Care Excellence (NICE) recommends UrgoStart (Urgo Medical) for treating venous leg ulcers as an adjunct therapy to the gold standard of compression therapy. Correct treatment choices must be made by clinicians using up-to-date relevant wound care knowledge. Evidence-based treatment algorithms and pathways can assist with correct product and therapy placement, assisting decision-making to improve patient outcomes. The present article describes a patient-centred leg ulcer pathway that embeds NICE guidance.

scholarly journals Wound bed preparation: a case series using polyhexanide and betaine solution and gel—a UK perspective

2020 ◽  
Vol 29 (7) ◽  
pp. 380-386
Author(s):  
Leanne Atkin ◽  
John Stephenson ◽  
Dawn M Cooper
Keyword(s):  
Chronic Wounds ◽  
Wound Care ◽  
Case Series ◽  
Wound Irrigation ◽  
Irrigation Solution ◽  
New Treatment ◽  
The Uk ◽  
Wound Bed Preparation ◽  
Dressing Change ◽  
Observation Period

Objective: The burden of wound care within the NHS is estimated at a cost of £5.3 billion per year and is set to rise annually by 30%. This case series describes the results of using polyhexanide (PHMB) and betaine wound irrigation solution and gels (Prontosan, B.Braun Medical Ltd., UK) across the UK in hard-to-heal (also described as chronic) wounds up to 20 years' duration, with an observation period of greater than one month. Over half of the hard-to-heal wounds were healed and vast improvements to all other wounds were observed. Improvements to wound bed condition were reported as early as two days after commencing initial treatment, with decreases in malodour, exudate, slough and pain reported across the case series. In addition to wound bed improvements, a reduction in dressing change frequency of 55% was observed in hard-to-heal wounds under the new treatment regime.

Electron microscopy of keratinocytes cultured on a collagen substrate used as an allograft for the treatment of chronic wounds

1992 ◽  
Vol 50 (2) ◽  
pp. 1104-1105
Author(s):  
Debby A. Jennings ◽  
Michael J. Morykwas ◽  
Louis C. Argenta
Keyword(s):  
Electron Microscopy ◽  
Cell Suspension ◽  
Single Cell ◽  
Chronic Wounds ◽  
Mechanical Stability ◽  
Uv Light ◽  
Type I ◽  
Single Cell Suspension ◽  
Collagen Substrate ◽  
Dermal Collagen

Grafts of cultured allogenic or autogenic keratlnocytes have proven to be an effective treatment of chronic wounds and burns. This study utilized a collagen substrate for keratinocyte and fibroblast attachment. The substrate provided mechanical stability and augmented graft manipulation onto the wound bed. Graft integrity was confirmed by light and transmission electron microscopy.Bovine Type I dermal collagen sheets (100 μm thick) were crosslinked with 254 nm UV light (13.5 Joules/cm2) to improve mechanical properties and reduce degradation. A single cell suspension of third passage neonatal foreskin fibroblasts were plated onto the collagen. Five days later, a single cell suspension of first passage neonatal foreskin keratinocytes were plated on the opposite side of the collagen. The grafts were cultured for one month.The grafts were fixed in phosphate buffered 4% formaldehyde/1% glutaraldehyde for 24 hours. Graft pieces were then washed in 0.13 M phosphate buffer, post-fixed in 1% osmium tetroxide, dehydrated, and embedded in Polybed 812.

The diagnosis and management of factor VIII and IX inhibitors: a guideline from the UK Haemophilia Centre Doctors' Organization (UKHCDO)

2000 ◽  
Vol 111 (1) ◽  
pp. 78-90 ◽  
Author(s):  
C. R. M. Hay ◽  
T. P. Baglin ◽  
P. W. Collins ◽  
F. G. H. Hill ◽  
D. M. Keeling
Keyword(s):  
Factor Viii ◽  
Diagnosis And Management ◽  
Viii And Ix ◽  
The Uk

1476: Prostate Cancer Detection in Men Aged 45-49 Years in the UK Protect (Prostate Testing for Cancer and Treatment) Trial

2006 ◽  
Vol 175 (4S) ◽  
pp. 476-477
Author(s):  
Freddie C. Hamdy ◽  
Joanne Howson ◽  
Athene Lane ◽  
Jenny L. Donovan ◽  
David E. Neal
Keyword(s):  
Prostate Cancer ◽  
Cancer Detection ◽  
Treatment Trial ◽  
Prostate Cancer Detection ◽  
The Uk

653: The Protect (Prostate Testing for Cancer and Treatment) Study: Evaluating Screening and Treatment of Clinically Localised Prostate Cancer in the UK

2006 ◽  
Vol 175 (4S) ◽  
pp. 210-210
Author(s):  
◽  
Freddie C. Hamdy ◽  
Athene Lane ◽  
David E. Neal ◽  
Malcolm Mason ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
The Uk
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