The Role of Family and Culture in Extreme Adversity: Psychosocial Response to the Ebola Virus Disease (EVD) Epidemic in Guinea, West Africa

Author(s):  
Neda Faregh ◽  
Alexis Tounkara ◽  
Kemo Soumaoro
2016 ◽  
Vol 18 (11) ◽  
Author(s):  
James M. Shultz ◽  
Janice L. Cooper ◽  
Florence Baingana ◽  
Maria A. Oquendo ◽  
Zelde Espinel ◽  
...  

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
T. R. W. Tipton ◽  
Y. Hall ◽  
J. A. Bore ◽  
A. White ◽  
L. S. Sibley ◽  
...  

AbstractZaireebolavirus (EBOV) is a highly pathogenic filovirus which can result in Ebola virus disease (EVD); a serious medical condition that presents as flu like symptoms but then often leads to more serious or fatal outcomes. The 2013–16 West Africa epidemic saw an unparalleled number of cases. Here we show characterisation and identification of T cell epitopes in surviving patients from Guinea to the EBOV glycoprotein. We perform interferon gamma (IFNγ) ELISpot using a glycoprotein peptide library to identify T cell epitopes and determine the CD4+ or CD8+ T cell component response. Additionally, we generate data on the T cell phenotype and measure polyfunctional cytokine secretion by these antigen specific cells. We show candidate peptides able to elicit a T cell response in EBOV survivors and provide inferred human leukocyte antigen (HLA) allele restriction. This data informs on the long-term T cell response to Ebola virus disease and highlights potentially important immunodominant peptides.


2016 ◽  
Vol 339 (11-12) ◽  
pp. 517-528 ◽  
Author(s):  
Alexandre Hassanin ◽  
Nicolas Nesi ◽  
Julie Marin ◽  
Blaise Kadjo ◽  
Xavier Pourrut ◽  
...  

Author(s):  
Nadege Goumkwa Mafopa ◽  
Gianluca Russo ◽  
Raoul Emeric Guetiya Wadoum ◽  
Emmanuel Iwerima ◽  
Vincent Batwala ◽  
...  

A serosurvey of anti-Ebola Zaire virus nucleoprotein IgG prevalence was carried out among Ebola virus disease survivors and their Community Contacts in Bombali District, Sierra Leone. Our data suggest that the specie of Ebola virus (Zaire) responsible of the 2013-2016 epidemic in West Africa may cause mild or asymptomatic infection in a proportion of cases, possibly due to an efficient immune response.


2014 ◽  
Vol 45 (1) ◽  
pp. 2-5 ◽  
Author(s):  
Colin Brown ◽  
Paul Arkell ◽  
Sakib Rokadiya

2018 ◽  
Vol 200 ◽  
pp. 166-173 ◽  
Author(s):  
Jesse Bonwitt ◽  
Michael Dawson ◽  
Martin Kandeh ◽  
Rashid Ansumana ◽  
Foday Sahr ◽  
...  

2019 ◽  
Vol 12 (1) ◽  
pp. 1662682 ◽  
Author(s):  
O. Alonge ◽  
S. Sonkarlay ◽  
W. Gwaikolo ◽  
C. Fahim ◽  
J. L. Cooper ◽  
...  

2019 ◽  
Vol 9 (4) ◽  
pp. 635-643
Author(s):  
Faith I. Edoror ◽  
Elizabeth O. Oloruntoba ◽  
Shade J. Akinsete

Abstract This study assessed the knowledge and perception of the role of water supply, sanitation and hygiene (WASH) in the containment of Ebola virus disease (EVD) among secondary school students in Ibadan, Nigeria. A cross-sectional study of 420 students from eight schools (public and private) in Ibadan was conducted. A semi-structured questionnaire and an observational checklist were used to collect data. Data were analysed using descriptive statistics, Chi-square test and logistic regression at 5% level of significance. Overall, 60% reported EVD was airborne. A majority (71%) of the respondents had good knowledge of EVD, while a majority (92%) had a good perception of the role of WASH in EVD containment. Class of respondents was significantly (p = 0.045) associated with knowledge of WASH. Although schools had satisfactory sanitary facilities, only a few (21%) sustained good hygiene practices at the end of the Ebola outbreak in Nigeria. Our findings revealed suboptimal knowledge on transmission of EVD, and unsustainable hygiene practices among secondary students post-Nigeria's EVD outbreak. High priority should be given to hygiene education among educators and students. Implementation of monitoring and evaluation of hygiene behaviour among secondary school students should also be a priority.


Author(s):  
Clement Adebajo Meseko ◽  
Adeniyi Olugbenga Egbetade ◽  
Shamsudeen Fagbo

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