A Crosstalk Between Dual-Specific Phosphatases and Dual-Specific Protein Kinases Can Be A Potential Therapeutic Target for Anti-cancer Therapy

2021 ◽  
pp. 357-382
Author(s):  
Basak Celtikci
Keyword(s):  
Cancer Therapy ◽  
Protein Kinases ◽  
Therapeutic Target ◽  
Specific Protein ◽  
Potential Therapeutic Target ◽  
Anti Cancer

SET Protein in Cancer: A Potential Therapeutic Target

2021 ◽  
Vol 21 ◽  
Author(s):  
Xinjie Liang ◽  
Xuefei Bao ◽  
Guoliang Chen
Keyword(s):  
Drug Resistance ◽  
Clinical Trials ◽  
Cancer Therapy ◽  
Tumor Cells ◽  
Strong Correlation ◽  
Therapeutic Target ◽  
Poor Prognosis ◽  
Therapeutic Options ◽  
Potential Therapeutic Target ◽  
Bona Fide

: SET protein is a multi-functional oncoprotein that is ubiquitously expressed in most tumor cells. Dysregulation of SET has been associated with many types of cancer. Due to ever-accumulating evidence of its strong correlation with both poor prognosis and drug resistance, the targeting of SET is starting to be explored. SET is currently regarded as a potential target for cancer therapy, and several inhibitors are being developed for clinical trials. In this review, the physiological and pathological functions of SET, as well as its antagonists, will be discussed along with the prospects and challenges involved with translating SET inhibitors into bona fide therapeutic options.

scholarly journals Oxidative phosphorylation as a potential therapeutic target for cancer therapy

2019 ◽  
Vol 146 (1) ◽  
pp. 10-17 ◽  
Author(s):  
Valentina Sica ◽  
José Manuel Bravo‐San Pedro ◽  
Gautier Stoll ◽  
Guido Kroemer
Keyword(s):  
Cancer Therapy ◽  
Oxidative Phosphorylation ◽  
Therapeutic Target ◽  
Potential Therapeutic Target

scholarly journals FBXO45 is a potential therapeutic target for cancer therapy

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Min Lin ◽  
Zhi-wei Wang ◽  
Xueqiong Zhu
Keyword(s):  
Cancer Therapy ◽  
Therapeutic Target ◽  
Potential Therapeutic Target

scholarly journals CD74 a Potential Therapeutic Target for Breast Cancer Therapy: Interferon Gamma Up-regulates its Expression in CAMA-1 and MDA-MB-231 Cancer Cells

2018 ◽  
Vol 14 (2) ◽  
pp. 58-69 ◽  
Author(s):  
Waleed Alabdulmon ◽  
Homaidan T. Alhomaidan ◽  
Zafar Rasheed ◽  
Inamul Hasan Madar ◽  
Noura Alasmael ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Therapy ◽  
Cancer Cells ◽  
Interferon Gamma ◽  
Therapeutic Target ◽  
Breast Cancer Therapy ◽  
Potential Therapeutic Target
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