Association of Different HTR2A, DRD4 Gene Genotypes with the Peculiarities of the Emotional and Personal Sphere of Russian Boys and Girls

2021 ◽  
pp. 771-780
Author(s):  
Elena Vorobyeva ◽  
Ekaterina Kovsh ◽  
Daria Alekseeva ◽  
Vitaly Babenko ◽  
Pavel Ermakov
Keyword(s):  
Drd4 Gene

Genetic polymorphism of dopamine receptor D4 (DRD4) gene in ten Indian rhesus macaques (Macaca mulatta mulatta)

Meta Gene ◽  
2021 ◽  
pp. 100891
Author(s):  
Sanjoy Kumar Chatterjee ◽  
Suniti Yadav ◽  
Kallur Nava Saraswathy ◽  
Prakash Ranjan Mondal
Keyword(s):  
Genetic Polymorphism ◽  
Dopamine Receptor ◽  
Macaca Mulatta ◽  
Rhesus Macaques ◽  
Drd4 Gene ◽  
Dopamine Receptor D4

scholarly journals DRD4 Gene Polymorphisms as a Risk Factor for Children with Attention Deficit Hyperactivity Disorder in Iranian Population

2017 ◽  
Vol 2017 ◽  
pp. 1-5
Author(s):  
Seyed Mahmoud Tabatabaei ◽  
Shahrokh Amiri ◽  
Sara Faghfouri ◽  
Seyed Gholamreza Noorazar ◽  
Shahin AbdollahiFakhim ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Tandem Repeats ◽  
Receptor Gene ◽  
Variable Number ◽  
Healthy Children ◽  
Drd4 Gene ◽  
Hyperactivity Disorder ◽  
Significant Difference ◽  
Northwest Of Iran

Background and Objective. Dopamine dysfunction is known to be associated with attention deficit hyperactivity disorder (ADHD). Dopamine D4 receptor gene (DRD4) is one of the important genes in this pathway. This study intended to investigate the variable number of tandem repeats (VNTR) in exon 3 of the DRD4 gene in Iranian children and adolescents. Materials and Methods. In this study, 130 children with ADHD, aged 6–14 years, and 130 healthy children, within the same age range, were enrolled. All children were selected from northwest of Iran which have Caucasian ethnic background and are of a Turkic ethnic group. VNTR polymorphisms of the DRD4 gene were evaluated by PCR using exon 3-specific primers followed by agarose gel electrophoresis. Findings. The Hardy-Weinberg principle and Chi-square test showed a significant difference in 4-repetition (4R) alleles between the ADHD (76.2%) and control (53.8%) groups (p=0.004; X2=17.39; df=5). The least percentage of repetition alleles in both groups was 2R. Conclusion. There is a significant correlation between the 4R alleles of DRD4 and ADHD in the northwest of Iran.

scholarly journals Identification and Characterization of a Tandem Repeat in Exon III of the Dopamine Receptor D4 (DRD4) Gene in Cetaceans

2006 ◽  
Vol 97 (3) ◽  
pp. 279-284 ◽  
Author(s):  
Line Mogensen ◽  
Carl Christian Kinze ◽  
Thomas Werge ◽  
Henrik Berg Rasmussen
Keyword(s):  
Dopamine Receptor ◽  
Tandem Repeat ◽  
Drd4 Gene ◽  
Identification And Characterization ◽  
Dopamine Receptor D4

scholarly journals Dopamine receptor DRD4 gene and stressful life events in persistent attention deficit hyperactivity disorder

2015 ◽  
Vol 168 (6) ◽  
pp. 480-491 ◽  
Author(s):  
Cristina Sánchez-Mora ◽  
Vanesa Richarte ◽  
Iris Garcia-Martínez ◽  
Mireia Pagerols ◽  
Montse Corrales ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Dopamine Receptor ◽  
Life Events ◽  
Attention Deficit ◽  
Stressful Life Events ◽  
Stressful Life ◽  
Drd4 Gene ◽  
Hyperactivity Disorder

scholarly journals Dopamine D4 receptor (DRD4) gene polymorphism is associated with attachment disorganization in infants

2000 ◽  
Vol 5 (6) ◽  
pp. 633-637 ◽  
Author(s):  
K Lakatos ◽  
I Toth ◽  
Z Nemoda ◽  
K Ney ◽  
M Sasvari-Szekely ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Dopamine D4 Receptor ◽  
Drd4 Gene ◽  
Attachment Disorganization ◽  
D4 Receptor

scholarly journals Gender-specific expression of the DRD4 gene on adolescent delinquency, anger and thrill seeking

2010 ◽  
Vol 6 (1) ◽  
pp. 82-89 ◽  
Author(s):  
Julia Dmitrieva ◽  
Chuansheng Chen ◽  
Ellen Greenberger ◽  
Oladele Ogunseitan ◽  
Yuan-Chun Ding
Keyword(s):  
Adolescent Delinquency ◽  
Drd4 Gene ◽  
Specific Expression ◽  
Thrill Seeking ◽  
Gender Specific

Symptoms of Attention-Deficit/Hyperactivity Disorder in Down Syndrome: Effects of the Dopamine Receptor D4 Gene

2015 ◽  
Vol 120 (1) ◽  
pp. 58-71 ◽  
Author(s):  
Gina Marie Mason ◽  
Goffredina Spanó ◽  
Jamie Edgin
Keyword(s):  
Down Syndrome ◽  
Individual Differences ◽  
Dopamine Receptor ◽  
Genetic Factors ◽  
Adhd Symptoms ◽  
Drd4 Gene ◽  
Allele Distribution ◽  
Children With Down Syndrome ◽  
Hyperactivity Disorder ◽  
Dopamine Receptor D4

Abstract This study examined individual differences in ADHD symptoms and executive function (EF) in children with Down syndrome (DS) in relation to the dopamine receptor D4 (DRD4) gene, a gene often linked to ADHD in people without DS. Participants included 68 individuals with DS (7-21 years), assessed through laboratory tasks, caregiver reports, and experimenter ratings. Saliva samples were collected from the DS group and 66 children without DS to compare DRD4 allele distribution, showing no difference between the groups. When the sample with DS was stratified for ethnicity (n  =  32), the DRD4 7-repeat allele significantly related to parent and experimenter ratings, but not to laboratory assessments. These results suggest that nontrisomy genetic factors may contribute to individual differences in ADHD symptoms in persons with DS.

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