Vitamin D, Metabolic Disorders and Reproduction

2014 ◽  
pp. 51-57
Author(s):  
Diana Jędrzejuk ◽  
Andrzej Milewicz ◽  
Felicja Lwow ◽  
Anna Brona
Keyword(s):  
Vitamin D ◽  
Metabolic Disorders

Salmon peptides limit obesity‐associated metabolic disorders by modulating a gut‐liver axis in vitamin D‐deficient mice

Obesity ◽  
2021 ◽  
Vol 29 (10) ◽  
pp. 1635-1649
Author(s):  
Marion Valle ◽  
Patricia L. Mitchell ◽  
Geneviève Pilon ◽  
Thibault Varin ◽  
Loïc Hénault ◽  
...  
Keyword(s):  
Vitamin D ◽  
Metabolic Disorders ◽  
Deficient Mice

scholarly journals Evaluation of Vitamin D Fractions in Obese Hypertensive Patients

2020 ◽  
Vol 17 (5) ◽  
pp. 1660
Author(s):  
Marta Pelczyńska ◽  
Teresa Grzelak ◽  
Marcelina Sperling ◽  
Matylda Kręgielska-Narożna ◽  
Paweł Bogdański ◽  
...  
Keyword(s):  
Vitamin D ◽  
Metabolic Disorders ◽  
Hdl Cholesterol ◽  
Predictive Marker ◽  
Lipid Profiles ◽  
Anthropometric Parameters ◽  
Hypertensive Patients ◽  
Hydroxyvitamin D ◽  
Glucose Levels ◽  
Free Vitamin D

Vitamin D fractions can be involved in the pathogenesis of metabolic disorders, but their concentrations are rarely determined. The aim of this study was to evaluate the concentration of vitamin D fractions in obese hypertensive patients and to determine its associations with anthropometric parameters, glucose levels, and lipid profiles. A total of 85 obese hypertensive patients (OBHT) and 40 nonobese nonhypertensive subjects (NOBNHT) underwent biochemical measurements of lipid profiles, glycemia, 25-hydroxyvitamin D (25(OH)D), free vitamin D (free25(OH)D), vitamin D binding protein, albumin levels. Moreover, free25(OH)D and bioavailable25(OH)D (bio25(OH)D) concentrations were calculated. Blood pressure and anthropometric measurements were performed. Differences between groups (p < 0.001) were found for 25(OH)D (OBHT 40.25 ± 18.02 vs. NOBNHT 64.10 ± 22.29 nmol/L), free25(OH)D (9.77 (7.46; 11.49) vs. 13.80 (10.34; 16.82) pmol/L), bioavailable 25(OH)D (3.7 (2.8; 4.4) vs. 5.4 (4.2; 6.7) nmol/L), and calculated free25(OH)D (7.82 (5.54; 11.64) vs. 10.46(8.06;16.28) pmol/L, p = 0.002). The OBHT patients showed no relationship between vitamin D fractions concentration and glucose or lipids level, although it was associated with anthropometric parameters. In the NOBNHT group, vitamin D fractions correlated positively with HDL cholesterol and negatively with triglyceridemia and hip circumference. Vitamin D fractions were decreased in obese hypertensive subjects, and were associated with anthropometric parameters, but not with glucose level or lipid profiles; they thus cannot be considered as a predictive marker of metabolic disorders in this group of patients.

scholarly journals Mineral nutrition of modern poultry genotypes

2009 ◽  
Vol 25 (5-6-1) ◽  
pp. 399-409 ◽  
Author(s):  
M. Lukic ◽  
Z. Pavlovski ◽  
Z. Skrbic
Keyword(s):  
Vitamin D ◽  
Particle Size ◽  
Mineral Nutrition ◽  
Metabolic Disorders ◽  
Practical Application ◽  
Genetic Progress ◽  
Adequate Nutrition ◽  
Factors Influencing ◽  
Micro Elements

In the latest research relating to mineral nutrition of poultry, the interest in several nutrients is prevailing for which in ordinary diets additional sources are necessary. In mineral nutrition of layers constantly the calcium (Ca) requirements are reviewed as one of the most important factors influencing the quality of eggs and bones, in regard to adequate level, source and particle size of added Ca, as well as mutual balance with other nutrients, primarily vitamin D, phosphorus (P) and certain micro-elements. Also, efforts are directed towards possibility and justification for use of new source of vitamin D, existing recommendations related to P are reviewed as well as increase of possibility for adoption of phytine bound phosphorus in diets using enzyme phytase, as well as investigation of organic forms of certain micro-element sources. Certain researches which combine the latest studies of the mineral nutrition of poultry are especially interesting also for practical application. Contrary to layers, focus of research of mineral nutrition of broilers is on phosphorus and application of enzyme phytase. In general, researches of the mineral nutrition of modern poultry genotypes are always actual, considering that their objective is to support genetic progress with adequate nutrition, but also to solve increasing problems relating to product quality, metabolic disorders and ecology.

scholarly journals Association of vitamin D insufficiency with adiposity and metabolic disorders in Brazilian adolescents

2013 ◽  
Vol 17 (4) ◽  
pp. 787-794 ◽  
Author(s):  
Renata MS Oliveira ◽  
Juliana F Novaes ◽  
Lorena M Azeredo ◽  
Ana Paula C Cândido ◽  
Isabel CG Leite
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Parathyroid Hormone ◽  
Metabolic Disorders ◽  
Central City ◽  
Vitamin D Insufficiency ◽  
Model Assessment ◽  
Cross Sectional ◽  
Vitamin D Intake ◽  
Dietary Record

AbstractObjectiveThe present study aimed to evaluate the frequency of deficiency/insufficiency of vitamin D in adolescents and its relationship to overweight and metabolic disorders.DesignCross-sectional study. Nutritional status was assessed by BMI according to WHO recommendations. Dietary intake was evaluated using a 3 d dietary record. The biochemical evaluation comprised measurements of serum lipids, lipoproteins, glucose, insulin, calcidiol (25(OH)D) and parathyroid hormone. Insulin resistance was calculated using the homeostasis model assessment. Body composition and blood pressure were assessed.SettingFifteen schools (eight public and seven private) in the central city of Juiz de Fora, Brazil.SubjectsThe analysis included a study population of 160 adolescents (seventy-seven eutrophic and eighty-three overweight) aged 15 to 17 years.ResultsVitamin D deficiency and insufficiency was observed in 1·25 and 70·6 % of adolescents, respectively. Serum 25(OH)D levels were statistically lower in adolescents with weight excess, abdominal obesity, hypercholesterolaemia, higher levels of parathyroid hormone, insulin resistance, hyperinsulinaemia and hypertension (P < 0·05). Lower BMI and waist circumference were observed in the third (highest) tertile of vitamin D intake for all adolescents. The high prevalence of vitamin D insufficiency is primarily nutritional and reflects a low vitamin D intake.ConclusionsOur results support the negative association among serum 25(OH)D levels and vitamin D intake with non-skeletal outcomes in Brazilian adolescents. Vitamin D fortification of foods and/or the use of vitamin D supplements need to be considered to raise vitamin D intake in the adolescent population, even in a sunny country like Brazil.

scholarly journals Association of vitamin D insufficiency with adiposity and metabolic disorders in Brazilian adolescents – Corrigendum

2013 ◽  
Vol 16 (8) ◽  
pp. 1525-1525 ◽  
Author(s):  
Renata MS Oliveira ◽  
Juliana F Novaes ◽  
Lorena M Azeredo ◽  
Ana Paula C Cândido ◽  
Isabel CG Leite
Keyword(s):  
Vitamin D ◽  
Metabolic Disorders ◽  
Vitamin D Insufficiency

scholarly journals Optimization of pharmacotherapy of patients with prostate adenoma with hormonal and metabolic disordes: correction of vitamin D deficiency with “Aquadetrim”

2019 ◽  
Vol 5 (4) ◽  
pp. 57-67
Author(s):  
Oleg I. Bratchikov ◽  
Igor A. Tyuzikov ◽  
Sergey O. Artishchev
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Metabolic Disorders ◽  
Main Group ◽  
Integrative Approach ◽  
Control Group ◽  
Practical Algorithms ◽  
Prostate Adenoma ◽  
Local Parameters

Introduction: Modern studies demonstrate an epidemiological and pathogenetic role of systemic hormonal and metabolic disorders in men with prostate adenoma (PA), so it is obvious that a pharmacotherapeutic correction of these disorders can increase the efficacy of the traditional therapy of the disease. Aim of study: To investigate the frequency, relationships among themselves and with PA local parameters of key systemic hormonal and metabolic disorders (obesity, insulin resistance, testosterone deficiency, vitamin D deficiency) and to develop practical algorithms for optimizing diagnosis and management based on an integrative approach. Material and Methods: The results of a comprehensive examination of 160 patients with PA (main group; average age 62.3 ± 4.2 years) and 30 healthy men without PA of the same age (control group), including: collection of anamnesis and complaints; questionnaires; physical, hormonal and sonographic studies, – are presented. Pharmacotherapeutic correction methods were tested in some patients of the main group. The data was processed using descriptive and comparative statistics. Results and Discussion: In the patients with PA, a significantly higher frequency of concomitant systemic hormonal and metabolic disorders formed at a younger age was established, compared to the men without PA, and significantly worse local characteristics of PA compared to the patients with PA without such (p &lt; 0.05). Reliable connections of some studied systemic hormonal and metabolic disorders with one another and with local parameters of PA (p &lt; 0.05) were revealed. A more severe vitamin D deficiency in the patients with PA compared to the control group was revealed, and the safety and a significant positive effect of its drug compensation on the parameters of hormonal and metabolic status and PA in D-deficient men with PA were shown (p &lt; 0.05). Conclusion: The results of the study confirm an important role of the studied systemic hormonal and metabolic disorders in the pathogenesis of PA and the need for their diagnosis and pharmacotherapeutic correction in all patients with PA on the basis of an integrative approach, according to the proposed algorithms.

scholarly journals High prevalence of vitamin D deficiency and its association with metabolic disorders in elderly patients

2017 ◽  
Vol 19 (4) ◽  
pp. 372-376 ◽  
Author(s):  
Małgorzata Koziarska-Rościszewska ◽  
Jacek Rysz ◽  
Mariusz Stępień
Keyword(s):  
Vitamin D ◽  
Elderly Patients ◽  
Vitamin D Deficiency ◽  
Metabolic Disorders ◽  
High Prevalence

The Effect of Extracellular Calcium Metabolism on Aldosterone Biosynthesis in Physiological and Pathological Status

2020 ◽  
Vol 52 (06) ◽  
pp. 448-453
Author(s):  
Xin Gao ◽  
Yuto Yamazaki ◽  
Yuta Tezuka ◽  
Kei Omata ◽  
Yoshikiyo Ono ◽  
...  
Keyword(s):  
Vitamin D ◽  
Parathyroid Hormone ◽  
Cardiovascular Diseases ◽  
Primary Aldosteronism ◽  
Calcium Metabolism ◽  
Metabolic Disorders ◽  
Metabolic Diseases ◽  
Extracellular Calcium ◽  
The Other ◽  
Potential Association

AbstractPrimary aldosteronism (PA) was reported to frequently harbor not only cardiovascular diseases but also some metabolic disorders including secondary calcium metabolic diseases. Recently, the potential association between aldosterone producing cells and systemic calcium metabolism has been proposed. For instance, PA is frequently associated with hypercalciuria or hypocalcemia, which subsequently stimulates parathyroid hormone (PTH) secretion. This altered calcium metabolism in PA patients could frequently result in secondary osteoporosis and fracture in some patients. On the other hand, extracellular calcium itself directly acts on adrenal cortex and has been also proposed as an independent regulator of aldosterone biosynthesis in human adrenals. However, it is also true that both PTH and vitamin D pathways stimulate endocrine functions of adrenal cortical adenomas to co-secret both aldosterone and cortisol. Therefore, it has become pivotal to explore the potential crosstalk between aldosterone and systemic calcium metabolism. We herein reviewed recent advances in these fields.

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