Geopedological and Landscape Dynamic Controls on Productivity Potentials and Constraints in Selected Spatial Entities in Sub-Saharan Africa

Author(s):  
Yazidhi Bamutaze
2020 ◽  
Vol 12 (12) ◽  
pp. 5112
Author(s):  
Linda Menk ◽  
Christian Neuwirth ◽  
Stefan Kienberger

Millions of people fall ill with malaria every year—most of them are located in sub-Saharan Africa. The weight of the burden of malaria on a society is determined by a complex interplay of environmental and social factors, including poverty, awareness and education, among others. A substantial share of the affected population is characterized by a general lack of anticipation and coping capacities, which renders them particularly vulnerable to the disease and its adverse side effects. This work aims at identifying interdependencies and feedback mechanisms in the malaria social vulnerability system and their variations in space by combining concepts, methods and tools from Climate Change Adaptation, Spatial Analysis, and Statistics and System Dynamics. The developed workflow is applied to a selected set of social, economic and biological vulnerability indicators covering five East-African Nations. As the study areas’ local conditions vary in a multitude of aspects, the social vulnerability system is assumed to vary accordingly throughout space. The study areas’ spatial entities were therefore aggregated into three system-regions using correlation-based clustering. Their respective correlation structures are displayed as Causal Loop Diagrams (CLDs). While the three resulting CLDs do not necessarily display causal relations (as the set of social vulnerability indicators are likely linked through third variables and parts of the data are proxies), they give a good overview of the data, can be used as basis for discussions in participatory settings and can potentially enhance the understanding the malaria vulnerability system.


2017 ◽  
Vol 1 (6) ◽  
pp. 533-537
Author(s):  
Lorenz von Seidlein ◽  
Borimas Hanboonkunupakarn ◽  
Podjanee Jittmala ◽  
Sasithon Pukrittayakamee

RTS,S/AS01 is the most advanced vaccine to prevent malaria. It is safe and moderately effective. A large pivotal phase III trial in over 15 000 young children in sub-Saharan Africa completed in 2014 showed that the vaccine could protect around one-third of children (aged 5–17 months) and one-fourth of infants (aged 6–12 weeks) from uncomplicated falciparum malaria. The European Medicines Agency approved licensing and programmatic roll-out of the RTSS vaccine in malaria endemic countries in sub-Saharan Africa. WHO is planning further studies in a large Malaria Vaccine Implementation Programme, in more than 400 000 young African children. With the changing malaria epidemiology in Africa resulting in older children at risk, alternative modes of employment are under evaluation, for example the use of RTS,S/AS01 in older children as part of seasonal malaria prophylaxis. Another strategy is combining mass drug administrations with mass vaccine campaigns for all age groups in regional malaria elimination campaigns. A phase II trial is ongoing to evaluate the safety and immunogenicity of the RTSS in combination with antimalarial drugs in Thailand. Such novel approaches aim to extract the maximum benefit from the well-documented, short-lasting protective efficacy of RTS,S/AS01.


1993 ◽  
Vol 47 (3) ◽  
pp. 555-556
Author(s):  
Lado Ruzicka

Crisis ◽  
2011 ◽  
Vol 32 (1) ◽  
pp. 43-51 ◽  
Author(s):  
Eugene Kinyanda ◽  
Ruth Kizza ◽  
Jonathan Levin ◽  
Sheila Ndyanabangi ◽  
Catherine Abbo

Background: Suicidal behavior in adolescence is a public health concern and has serious consequences for adolescents and their families. There is, however, a paucity of data on this subject from sub-Saharan Africa, hence the need for this study. Aims: A cross-sectional multistage survey to investigate adolescent suicidality among other things was undertaken in rural northeastern Uganda. Methods: A structured protocol administered by trained psychiatric nurses collected information on sociodemographics, mental disorders (DSM-IV criteria), and psychological and psychosocial risk factors for children aged 3–19 years (N = 1492). For the purposes of this paper, an analysis of a subsample of adolescents (aged 10–19 years; n = 897) was undertaken. Results: Lifetime suicidality in this study was 6.1% (95% CI, 4.6%–7.9%). Conclusions: Factors significantly associated with suicidality included mental disorder, the ecological factor district of residence, factors suggestive of low socioeconomic status, and disadvantaged childhood experiences.


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