Putative Precursor Lesions of Gestational Trophoblastic Neoplasia

2016 ◽  
pp. 85-102
Author(s):  
Natalia Buza ◽  
Pei Hui
Keyword(s):  
Gestational Trophoblastic Neoplasia ◽  
Precursor Lesions ◽  
Putative Precursor

Allelotyping Nephrogenic Rests: Putative Precursor Lesions of Wilms Tumors

1999 ◽  
Vol 2 (5) ◽  
pp. 488-489 ◽  
Author(s):  
Anirban Maitra ◽  
Syed Salahuddin ◽  
Charles F. Timmons ◽  
Adi F. Gazdar
Keyword(s):  
Precursor Lesions ◽  
Putative Precursor ◽  
Nephrogenic Rests

scholarly journals Precursor Lesions of High-Grade Serous Ovarian Carcinoma: Morphological and Molecular Characteristics

2010 ◽  
Vol 2010 ◽  
pp. 1-9 ◽  
Author(s):  
Amy L. Gross ◽  
Robert J. Kurman ◽  
Russell Vang ◽  
Ie-Ming Shih ◽  
Kala Visvanathan
Keyword(s):  
Fallopian Tube ◽  
Screening Tools ◽  
Serous Carcinoma ◽  
Molecular Characteristics ◽  
High Grade ◽  
Precursor Lesions ◽  
Serous Ovarian Carcinoma ◽  
Brca 1 ◽  
Putative Precursor ◽  
Intraepithelial Lesions

The lack of proven screening tools for early detection and the high mortality of ovarian serous carcinoma (OSC), particularly high grade, have focused attention on identifying putative precursor lesions with distinct morphological and molecular characteristics. The finding of occult invasive and intraepithelial fallopian tube carcinomas in prophylactically removed specimens from asymptomatic high-risk BRCA 1/2-mutation carriers supports the notion of an origin for OSC in the fallopian tube. The intraepithelial carcinomas have been referred to as serous intraepithelial carcinomas (STICs) but our own findings (unpublished data) and recent reports have drawn attention to a spectrum of changes that fall short of STICs that we have designated serous tubal intraepithelial lesions (STILs).

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