Finite Element Model for Hydrocephalus and Idiopathic Intracranial Hypertension

Author(s):  
Dong-Joo Kim ◽  
Hakseung Kim ◽  
Dae-Hyeon Park ◽  
Hack-Jin Lee ◽  
Zofia Czosnyka ◽  
...  
2015 ◽  
Vol 122 (6) ◽  
pp. 1330-1340 ◽  
Author(s):  
Hakseung Kim ◽  
Byoung-Kyong Min ◽  
Dae-Hyeon Park ◽  
Stanley Hawi ◽  
Byung-Jo Kim ◽  
...  

OBJECT Brain deformation can be seen in hydrocephalus and idiopathic intracranial hypertension (IIH) via medical images. The phenomenology of local effects, brain shift, and raised intracranial pressure and herniation are textbook concepts. However, there are still uncertainties regarding the specific processes that occur when brain tissue is subject to the mechanical stress of different temporal and spatial profiles of the 2 neurological disorders. Moreover, recent studies suggest that IIH and hydrocephalus may be diseases with opposite pathogenesis. Nevertheless, the similarities and differences between the 2 subjects have not been thoroughly investigated. METHODS An anatomical porohyperelastic finite element model was used to assess the brain tissue responses associated with hydrocephalus and IIH. The same set of boundary conditions, with the exception of brain loading for development of the transmantle pressure gradient, was applied for the 2 models. The distribution of stress and strain during tissue distortion is described by the mechanical parameters. RESULTS The results of both the hydrocephalus and IIH models correlated with pathological characteristics. For the hydrocephalus model, periventricular edema was associated with the presence of positive volumetric strain and void ratio in the lateral ventricle horns. By contrast, the IIH model revealed edema across the cerebral mantle, including the centrum semiovale, with a positive void ratio and volumetric strain. CONCLUSIONS The model simulates all the clinical features in correlation with the MR images obtained in patients with hydrocephalus and IIH, thus providing support for the role of the transmantle pressure gradient and capillary CSF absorption in CSF-related brain deformation. The finite element methods can be used for a better understanding of the pathophysiological mechanisms of neurological disorders associated with parenchymal volumetric fluctuation.


1986 ◽  
Vol 19 (4) ◽  
pp. 807-824
Author(s):  
Wayne F. Larrabee ◽  
J.A. Galt

2021 ◽  
Vol 26 (3) ◽  
pp. 04021002
Author(s):  
Yifan Xie ◽  
Zhenze Xie ◽  
Jichun Wu ◽  
Yong Chang ◽  
Chunhong Xie ◽  
...  

1989 ◽  
Vol 17 (4) ◽  
pp. 305-325 ◽  
Author(s):  
N. T. Tseng ◽  
R. G. Pelle ◽  
J. P. Chang

Abstract A finite element model was developed to simulate the tire-rim interface. Elastomers were modeled by nonlinear incompressible elements, whereas plies were simulated by cord-rubber composite elements. Gap elements were used to simulate the opening between tire and rim at zero inflation pressure. This opening closed when the inflation pressure was increased gradually. The predicted distribution of contact pressure at the tire-rim interface agreed very well with the available experimental measurements. Several variations of the tire-rim interference fit were analyzed.


1996 ◽  
Vol 24 (4) ◽  
pp. 339-348 ◽  
Author(s):  
R. M. V. Pidaparti

Abstract A three-dimensional (3D) beam finite element model was developed to investigate the torsional stiffness of a twisted steel-reinforced cord-rubber belt structure. The present 3D beam element takes into account the coupled extension, bending, and twisting deformations characteristic of the complex behavior of cord-rubber composite structures. The extension-twisting coupling due to the twisted nature of the cords was also considered in the finite element model. The results of torsional stiffness obtained from the finite element analysis for twisted cords and the two-ply steel cord-rubber belt structure are compared to the experimental data and other alternate solutions available in the literature. The effects of cord orientation, anisotropy, and rubber core surrounding the twisted cords on the torsional stiffness properties are presented and discussed.


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