There is extensive research of the Ephemeroptera communities taxonomy and ecology in the Andean region of Colombia. However, other regions such as the Orinoquia have been insufficiently studied. From this region, in the Meta department, four species have been registered: Varipes lasiobrachius Lugo-Ortiz & McCafferty, Coryphorus aquilus Peters, Miroculis (Atroari) colombiensis Savage & Peters and Tricorythopsis rondoniensis (Dias, Cruz & Ferreira). The main objective of this study is to report for the first time for this region the species: Mayobaetis ellenae (Mayo), Hydrosmylodon primanus (Eaton), Haplohyphes baritu Domínguez, Camelobaetidus edmundsi Dominique, Mathuriau & Thomas and Nanomis galera Lugo-Ortiz & McCafferty.