Bidirectional Communication for Effective Human-Agent Teaming

Author(s):  
Amar R. Marathe ◽  
Kristin E. Schaefer ◽  
Arthur W. Evans ◽  
Jason S. Metcalfe
2020 ◽  
Vol 57 (12) ◽  
pp. 5026-5043 ◽  
Author(s):  
Shan Liu ◽  
Jiguo Gao ◽  
Mingqin Zhu ◽  
Kangding Liu ◽  
Hong-Liang Zhang

Abstract Understanding how gut flora influences gut-brain communications has been the subject of significant research over the past decade. The broadening of the term “microbiota-gut-brain axis” from “gut-brain axis” underscores a bidirectional communication system between the gut and the brain. The microbiota-gut-brain axis involves metabolic, endocrine, neural, and immune pathways which are crucial for the maintenance of brain homeostasis. Alterations in the composition of gut microbiota are associated with multiple neuropsychiatric disorders. Although a causal relationship between gut dysbiosis and neural dysfunction remains elusive, emerging evidence indicates that gut dysbiosis may promote amyloid-beta aggregation, neuroinflammation, oxidative stress, and insulin resistance in the pathogenesis of Alzheimer’s disease (AD). Illustration of the mechanisms underlying the regulation by gut microbiota may pave the way for developing novel therapeutic strategies for AD. In this narrative review, we provide an overview of gut microbiota and their dysregulation in the pathogenesis of AD. Novel insights into the modification of gut microbiota composition as a preventive or therapeutic approach for AD are highlighted.


Author(s):  
Guillaume Dubuisson Duplessis ◽  
Caroline Langlet ◽  
Chloé Clavel ◽  
Frédéric Landragin

Author(s):  
Joanna Mania ◽  
Fieke Miedema ◽  
Rose Browne ◽  
Joost Broekens ◽  
Catharine Oertel

2021 ◽  
pp. 002436392110176
Author(s):  
Nicanor Pier Giorgio Austriaco

In recent months, there has been a lot of debate surrounding the use of those COVID-19 vaccines that have been either tested or manufactured with cell lines that were isolated from the remains of an aborted fetal child. Most faithful and orthodox Catholic moral theologians, among whom I count myself, have concluded that their use is not intrinsically evil. Therefore, like every other decision that falls into the category of actions that are not intrinsically evil, the decision to be vaccinated with these morally controversial vaccines has to be governed by the virtue of prudence. It is a decision that calls for a wisdom that properly sees this action within the constellation of actions that propels the human agent to the heights of holiness. This is why prayer is so essential for authentic moral judgment. With prayer, we ask the Holy Spirit who is the all-prudent one to guide our actions so that we can choose and act well not only for our only well-being but for the well-being of all. Acts that are not themselves intrinsically evil are deemed virtuous or not within the narrative of the individual person’s life.


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