Discovery and Integration of Organ-Failure Episodes in Mortality Prediction

2007 ◽  
pp. 97-106 ◽  
Author(s):  
Tudor Toma ◽  
Ameen Abu-Hanna ◽  
Robert-Jan Bosman
Keyword(s):  
Organ Failure ◽  
Mortality Prediction ◽  
Discovery And Integration

scholarly journals Accuracy of conventional and novel scoring systems in predicting severity and outcomes of acute pancreatitis: a retrospective study

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Qing Wu ◽  
Jie Wang ◽  
Mengbin Qin ◽  
Huiying Yang ◽  
Zhihai Liang ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Organ Failure ◽  
Scoring System ◽  
Characteristic Curve ◽  
Failure Prediction ◽  
Scoring Systems ◽  
Mortality Prediction ◽  
Severity Prediction ◽  
Index Of Severity ◽  
Glasgow Score

Abstract Background Recently, several novel scoring systems have been developed to evaluate the severity and outcomes of acute pancreatitis. This study aimed to compare the effectiveness of novel and conventional scoring systems in predicting the severity and outcomes of acute pancreatitis. Methods Patients treated between January 2003 and August 2020 were reviewed. The Ranson score (RS), Glasgow score (GS), bedside index of severity in acute pancreatitis (BISAP), pancreatic activity scoring system (PASS), and Chinese simple scoring system (CSSS) were determined within 48 h after admission. Multivariate logistic regression was used for severity, mortality, and organ failure prediction. Optimum cutoffs were identified using receiver operating characteristic curve analysis. Results A total of 1848 patients were included. The areas under the curve (AUCs) of RS, GS, BISAP, PASS, and CSSS for severity prediction were 0.861, 0.865, 0.829, 0.778, and 0.816, respectively. The corresponding AUCs for mortality prediction were 0.693, 0.736, 0.789, 0.858, and 0.759. The corresponding AUCs for acute respiratory distress syndrome prediction were 0.745, 0.784, 0.834, 0.936, and 0.820. Finally, the corresponding AUCs for acute renal failure prediction were 0.707, 0.734, 0.781, 0.868, and 0.816. Conclusions RS and GS predicted severity better than they predicted mortality and organ failure, while PASS predicted mortality and organ failure better. BISAP and CSSS performed equally well in severity and outcome predictions.

scholarly journals Haemogram-Derived Indices for Screening and Prognostication in Critically Ill Septic Shock Patients: A Case-Control Study

Diagnostics ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 638
Author(s):  
Piotr S. Liberski ◽  
Michał Szewczyk ◽  
Łukasz J. Krzych
Keyword(s):  
Septic Shock ◽  
Organ Failure ◽  
Simplified Acute Physiology Score ◽  
Mortality Prediction ◽  
Apache Ii ◽  
Icu Mortality ◽  
Reactive Protein ◽  
Saps Ii ◽  
Multi Organ Failure ◽  
Failure Assessment

This study aimed (1) to assess the diagnostic accuracy of neutrophil-to-lymphocyte (NLR), platelet-to-lymphocyte (PLR), monocyte-to-lymphocyte (MLR) and platelet count-to-mean platelet volume (PLT/MPV) ratios in predicting septic shock in patients on admission to the intensive care unit (ICU) and (2) to compare it with the role of C-reactive protein (CRP), procalcitonin (PCT) and lactate level. We also sought (3) to verify whether the indices could be useful in ICU mortality prediction and (4) to compare them with Acute Physiology and Chronic Health Evaluation II (APACHE II), Simplified Acute Physiology Score II (SAPS II) and Sequential Organ Failure Assessment (SOFA) scores. This retrospective study covered 138 patients, including 61 subjects with multi-organ failure due to septic shock (study group) and 77 sex- and age-matched controls. Septic patients had significantly higher NLR (p < 0.01) and NLR predicted septic shock occurrence (area under the ROC curve, AUROC = 0.66; 95% CI 0.58–0.74). PLR, MLR and PLT/MPV were impractical in sepsis prediction. Combination of CRP with NLR improved septic shock prediction (AUROC = 0.88; 95% CI 0.81–0.93). All indices failed to predict ICU mortality. APACHE II and SAPS II predicted mortality with AUROC = 0.68; 95% CI 0.54–0.78 and AUROC = 0.7; 95% CI 0.57–0.81, respectively. High NLR may be useful to identify patients with multi-organ failure due to septic shock but should be interpreted along with CRP or PCT. The investigated indices are not related with mortality in this specific clinical setting.

OR60: Gastrointestinal Organ Failure Symptoms Included in Sofa Scores Improve Mortality Prediction in the ICU: A Mathematical Approach

2017 ◽  
Vol 36 ◽  
pp. S24
Author(s):  
P. Singer ◽  
L. Cohen Fox ◽  
Y. Aperstein ◽  
J. Cohen ◽  
M. Theilla ◽  
...  
Keyword(s):  
Organ Failure ◽  
Mortality Prediction ◽  
Mathematical Approach

Comparing Mortality Prediction by Quick Sequential Organ Failure Assessment With Emergency Physician Judgment

Shock ◽  
2019 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
William R. Cleek ◽  
Nicholas J. Johnson ◽  
Bjorn K. Watsjold ◽  
M. Kennedy Hall ◽  
Daniel J. Henning
Keyword(s):  
Sequential Organ Failure Assessment ◽  
Organ Failure ◽  
Emergency Physician ◽  
Mortality Prediction ◽  
Failure Assessment ◽  
Physician Judgment
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