The Glycocode: Translating Heparan Sulfate Fine Structure into Developmental Function

2013 ◽  
pp. 3-18
Author(s):  
Adam B. Cadwallader ◽  
H. Joseph Yost
Keyword(s):  
Fine Structure ◽  
Heparan Sulfate

scholarly journals Fine structure of heparan sulfate regulates syndecan-1 function and cell behavior.

1994 ◽  
Vol 269 (18) ◽  
pp. 13100-13106
Author(s):  
R.D. Sanderson ◽  
J.E. Turnbull ◽  
J.T. Gallagher ◽  
A.D. Lander
Keyword(s):  
Fine Structure ◽  
Heparan Sulfate ◽  
Cell Behavior

scholarly journals Interactions between heparan sulfate and proteins: the concept of specificity

2006 ◽  
Vol 174 (3) ◽  
pp. 323-327 ◽  
Author(s):  
Johan Kreuger ◽  
Dorothe Spillmann ◽  
Jin-ping Li ◽  
Ulf Lindahl
Keyword(s):  
Fine Structure ◽  
Growth Factors ◽  
Protein Binding ◽  
Heparan Sulfate ◽  
Cell Survival ◽  
Genetic Information

Proteoglycan (PG) coreceptors carry heparan sulfate (HS) chains that mediate interactions with growth factors, morphogens, and receptors. Thus, PGs modulate fundamental processes such as cell survival, division, adhesion, migration, and differentiation. This review summarizes recent biochemical and genetic information that sheds new light on the nature of HS–protein binding. Unexpectedly, many interactions appear to depend more on the overall organization of HS domains than on their fine structure.

scholarly journals Lymphatic Specific Disruption in the Fine Structure of Heparan Sulfate Inhibits Dendritic Cell Traffic and Functional T Cell Responses in the Lymph Node

2014 ◽  
Vol 192 (5) ◽  
pp. 2133-2142 ◽  
Author(s):  
Xin Yin ◽  
Scott C. Johns ◽  
Daniel Kim ◽  
Zbigniew Mikulski ◽  
Catherina L. Salanga ◽  
...  
Keyword(s):  
Fine Structure ◽  
Lymph Node ◽  
T Cell ◽  
Dendritic Cell ◽  
Heparan Sulfate ◽  
T Cell Responses ◽  
Cell Responses

scholarly journals Light-induced 3-O-Sulfotransferase Expression Alters Pineal Heparan Sulfate Fine Structure

2003 ◽  
Vol 279 (7) ◽  
pp. 5053-5054 ◽  
Author(s):  
Balagurunathan Kuberan ◽  
Miroslaw Lech ◽  
Jimo Borjigin ◽  
Robert D. Rosenberg
Keyword(s):  
Fine Structure ◽  
Heparan Sulfate

Perlecan heparan‐sulfate fine structure and SHH signaling in advanced prostate cancer

2007 ◽  
Vol 21 (5) ◽  
Author(s):  
Brent Ferguson ◽  
Michael Schlicht ◽  
Alexandra Migdal ◽  
Payal Shaw ◽  
Milton W. Datta ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Fine Structure ◽  
Heparan Sulfate ◽  
Advanced Prostate Cancer ◽  
Shh Signaling

scholarly journals Cell surface syndecan-1 on distinct cell types differs in fine structure and ligand binding of its heparan sulfate chains.

1994 ◽  
Vol 269 (29) ◽  
pp. 18881-18890 ◽  
Author(s):  
M. Kato ◽  
H. Wang ◽  
M. Bernfield ◽  
J.T. Gallagher ◽  
J.E. Turnbull
Keyword(s):  
Fine Structure ◽  
Cell Surface ◽  
Ligand Binding ◽  
Heparan Sulfate ◽  
Cell Types ◽  
Distinct Cell

Fine Structure of Platelet Interaction with a New Microcrystalline Collagen Preparation

1974 ◽  
Vol 32 ◽  
pp. 58-59
Author(s):  
W. H. Zucker ◽  
R. G. Mason
Keyword(s):  
Fine Structure ◽  
Platelet Aggregation ◽  
Hydrochloric Acid ◽  
Whole Blood ◽  
Platelet Adhesion ◽  
Hemostatic Agent ◽  
Native Collagen ◽  
Fibrillar Morphology ◽  
Clinical Interest ◽  
New Form

Platelet adhesion initiates platelet aggregation and is an important component of the hemostatic process. Since the development of a new form of collagen as a topical hemostatic agent is of both basic and clinical interest, an ultrastructural and hematologic study of the interaction of platelets with the microcrystalline collagen preparation was undertaken.In this study, whole blood anticoagulated with EDTA was used in order to inhibit aggregation and permit study of platelet adhesion to collagen as an isolated event. The microcrystalline collagen was prepared from bovine dermal corium; milling was with sharp blades. The preparation consists of partial hydrochloric acid amine collagen salts and retains much of the fibrillar morphology of native collagen.

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