Characterization of Physicochemical Parameters in Toxicology

2021 ◽  
pp. 1-8
Author(s):  
Mathias Locher
Author(s):  
Vanya Manolova ◽  
Ivayla Parvina ◽  
Todorka Yankovska Stefanova ◽  
Elissaveta Luchanska ◽  
Ralitsa Balkanska

2016 ◽  
Vol 18 (2) ◽  
pp. 131-139
Author(s):  
Kinga Łuczka ◽  
Barbara Grzmil ◽  
Bogumił Kic ◽  
Krzysztof Kowalczyk

Abstract Synthesis and characterization of the aluminum phosphates modified with ammonium, calcium and molybdenum were conducted. The influence of process parameters (reactive pressure and molar ratios) in the reaction mixture were studied. The contents of the individual components in the products were in the range of: 10.97–17.31 wt% Al, 2.65–13.32 wt% Ca, 0.70–3.11 wt% Mo, 4.36–8.38 wt% NH3, and 35.12–50.54 wt% P2O5. The materials obtained in the experiments were characterized by various physicochemical parameters. The absorption oil number was in the range from 67 to 89 of oil/100 g of product, the surface area was within the range of 4–76 m2/g, whereas the average particle size of products reached 282–370 nm. The Tafel tests revealed comparable anticorrosive properties of aluminum phosphates modified with ammonium, calcium, molybdenum in comparison with commercial phosphate.


Author(s):  
Swati Sharma ◽  
Dileep Singh Baghel ◽  
Saurabh Singh ◽  
Sachin Kumar Singh

  Objective: This is aimed to study the development of different dosage form and physicochemical characterization of Trikantakadi Kvatha (TK).Methods: Stability, shelf life, non-convenient, and large dosages administration are the major concern for Kvatha. To overcome these problems, an effort has been made to modify the formulation without changing its efficacy into various dosage forms such as tablet, syrup, and tincture. Comparative pharmacognostic, physicochemical, and phytochemical parameters of crude herbs and prepared formulations were investigated. TK was prepared by classical method mentioned in literature and converted into TK syrup, TK Ghana vati, and Trikantakadi tincture (TT). Precaution should be taken during the processing of formulations. TT placed at a dark place in airtight container.Results: Physicochemical and phytochemical investigations are not shown any remarkable variations with various prepared dosage forms. The Rf range observed between the 0.08 and 0.80 follows the standard value when compared with the reference of plant drug used for the preparation of dosage form.Conclusion: The prepared dosages forms were not exhibited any remarkable difference according to thin-layer chromatography studies and physicochemical parameters. However, the developed dosage forms are more stable than kvatha.


2005 ◽  
Vol 40 (1) ◽  
pp. 51-58 ◽  
Author(s):  
Olivier Thomas ◽  
Estelle Baurès ◽  
Marie-Florence Pouet

Abstract The composition of water and wastewater, varying temporally and spatially, depends on factors such as environmental context, types of pollution sources, weather conditions leading to dilution or solids transportation, length of sewer network, etc. Because quantitative parameters are often not adapted for the characterization of wastewater quality variability, a non-parametric measurement is proposed, based on comparison of the UV absorption spectra of samples. The presence of isosbestic points, occurring in the set of spectra either directly or indirectly after normalization, allows quantification of the variability of a given water or effluent. A normalization step is used when dilution exists in the case of a mixture of water types (discharge or rain). Several examples show how to calculate the variability or to estimate the dilution factor from UV spectra data, even without results of physicochemical parameters.


1996 ◽  
Vol 42 (3) ◽  
pp. 259-266 ◽  
Author(s):  
C. Tardy-Jacquenod ◽  
P. Caumette ◽  
R. Matheron ◽  
C. Lanau ◽  
O. Arnauld ◽  
...  

The occurrence and metabolic capacities of sulfate-reducing bacteria (SRB) were studied in 23 water samples taken from producing wells at 14 different sites. Oil fields in France, the North Sea, and the Gulf of Guinea were selected and classified according to physicochemical parameters (salinity ranging from 0.3 to 120 g∙L−1 and temperature between 29 and 85 °C). After the distribution of SRB within oil fields was studied, several strains of SRB were isolated and characterized metabolically. Twenty of the thirty-seven strains were not related to any known species. Most of the identified strains were members of the genera Desulfovibrio and Desulfotomaculum by molecular, morphological, and physiological properties.Key words: sulfate-reducing bacteria, oil-field ecology, metabolic identification, biodiversity.


2019 ◽  
Vol 56 (8) ◽  
pp. 3646-3659 ◽  
Author(s):  
Vassilios K. Karabagias ◽  
Ioannis K. Karabagias ◽  
Ilias Gatzias ◽  
Kyriakos A. Riganakos

2021 ◽  
Vol 101 (1) ◽  
pp. 61-70
Author(s):  
Ye.M. Tazhbayev ◽  
◽  
A.R. Galiyeva ◽  
T.S. Zhumagaliyeva ◽  
M.Zh. Burkeyev ◽  
...  

This article considers someaspects of synthesis and characterizationof polylactide-co-glycolide nanoparticles immobilized withthe antituberculous drug isoniazid. The influence of some synthesis parameters of nanoparticles (the ratio of drug substance:polymer and surfactant concentration) onproperties of the obtained nanosomal drug form of isoniazid has been studied. Optimal conditions for obtainingthenanoparticles with the best physicochemical parameters such as: particle size, polydispersity, conversion, etc. have been found. These nanoparticlescan be used asdrug carriers.The results revealed thata polymer: drug ratio of 1:1 and the use of 3% Twin 80 are necessaryto obtain stable emulsions of nanoparticles of polylactide-co-glycolide with satisfactory characteristics. Average size of the obtained particles was 196.4 nm,and the polydispersity value was 0.323. The aggregation stability of nanoparticles during 4 hours at temperatures of 4ºC and 20ºC has been evaluated. The morphology of the obtained nanoparticles has been studied.Analysis of nanoparticles was characterized by various instrumental methods includinggas chromatography and thermogravimetrytechniques. The resulting nanoparticles of polylactide-co-glycolide immobilized with isoniazid are stable in time andcanprolong the action of the drug. In vitrorelease of isoniazid from polylactide-co-glycolide nanoparticles hasbeen studied.


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