Function of Ion Channels and Cytosolic Ca2+ in the Mediation of Higher Plant Cell Ion Transport

Author(s):  
Julian I. Schroeder
1986 ◽  
Vol 250 (3) ◽  
pp. F379-F385 ◽  
Author(s):  
L. G. Palmer

The patch-clamp technique of Neher and Sakmann and their colleagues has been widely used over the last 5 years to investigate ion channels in excitable tissues. More recently, it has become useful as a tool to study channels involved in transepithelial ion transport. In this review, I briefly cover the basic concepts behind the patch-clamp technique and the kinds of information that can be obtained with it. I then summarize the applications of the technique to renal tissues and describe some of the channel types that have been observed to date in epithelia.


2019 ◽  
Vol 25 (55) ◽  
pp. 12795-12800
Author(s):  
Tianliang Xiao ◽  
Jing Ma ◽  
Jiaqiao Jiang ◽  
Mengke Gan ◽  
Bingxin Lu ◽  
...  
Keyword(s):  

PROTOPLASMA ◽  
1988 ◽  
Vol 143 (2-3) ◽  
pp. 165-169 ◽  
Author(s):  
G. Nagahashi ◽  
Linda Garzarella

1986 ◽  
Vol 25 (6) ◽  
pp. 1515
Author(s):  
Jeffrey B. Harborne

1987 ◽  
Vol 1 (5-6) ◽  
pp. 473-475 ◽  
Author(s):  
P. Touchard ◽  
C. Ripoll ◽  
C. Morvan ◽  
M. Demarty

2014 ◽  
Vol 369 (1638) ◽  
pp. 20130102 ◽  
Author(s):  
Albrecht Schwab ◽  
Christian Stock

Cell migration is a central component of the metastatic cascade requiring a concerted action of ion channels and transporters (migration-associated transportome), cytoskeletal elements and signalling cascades. Ion transport proteins and aquaporins contribute to tumour cell migration and invasion among other things by inducing local volume changes and/or by modulating Ca 2+ and H + signalling. Targeting cell migration therapeutically bears great clinical potential, because it is a prerequisite for metastasis. Ion transport proteins appear to be attractive candidate target proteins for this purpose because they are easily accessible as membrane proteins and often overexpressed or activated in cancer. Importantly, a number of clinically widely used drugs are available whose anticipated efficacy as anti-tumour drugs, however, has now only begun to be evaluated.


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