Static Automated Perimetry in the Follow-Up of Lens Opacities

Purpose To determine the correlation between neuroretinal rim area and functional losses detected by short-wavelength automated perimetry (SWAP) in a population of patients with suspected glaucoma. Methods Forty-two eyes of 42 ocular hypertensive subjects who met the selection criteria (intraocular pressure greater than 21 mm of Hg and normal conventional visual fields) were studied. A planimetric optic nerve head study was performed, determining the total and sectorized neuroretinal rim areas. SWAP was also done, with a modified Humphrey field analyzer. Results There were no significant correlations between the neuroretinal rim areas and the global perimetric parameters. However, the correlations between the inferotemporal neuroretinal rim area and some superonasal visual field regions (areas 3 and 4) were significant. Conclusions There is a relation in the topography of some visual field areas assessed by SWAP and the inferotemporal neuroretinal rim area, which may play a role in the diagnosis and follow-up of suspected glaucoma.

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User Friendliness of a Wearable Visual Behavior Monitor for Cataract and Refractive Surgery

Applied Sciences ◽

10.3390/app10062190 ◽

2020 ◽

Vol 10 (6) ◽

pp. 2190 ◽

Cited By ~ 1

Author(s):

Bojan Pajic ◽

Pavel Zakharov ◽

Brigitte Pajic-Eggspuehler ◽

Zeljka Cvejic

Keyword(s):

Refractive Surgery ◽

Diagnostic Testing ◽

Wearable Device ◽

Daily Activities ◽

Visual Behavior ◽

User Friendliness ◽

Refractive Lens Exchange ◽

Refractive Lens ◽

Lens Opacities

A prospective feasibility study was conducted to determine whether a new wearable device, the Visual Behavior Monitor (VBM), was easy to use and did not present any difficulties with the daily activities of patients. Patients for cataract surgery and refractive lens exchange were randomly selected and screened for inclusion in the study. A total of 129 patients were included in the study as part of a multicenter study. All measurements were performed before surgery. Upon inclusion, patients were trained to wear the device, instructed to wear it for a minimum of 36 h, and were scheduled to return in one week. The VBM measures the distance at which patients’ visual activities are performed, the level of illumination, and head translational and rotational movements along the three axes. On the follow-up visit, patients completed a questionnaire about their experience in wearing the device. All patients underwent standard diagnostic testing, with their cataract grade determined by the Lens Opacities Classification System (LOCS) classification. Results indicate that 87% of patients felt comfortable using the wearable device while 8% of patients responded as not feeling comfortable (5% of patients did not respond to the question). In addition, 91% of patients found it easy to attach the wearable to the magnetic clip while 4% of patients did not find it easy, and 5% of patients did not respond. Overall, patients found the device easy to use, with most reporting that the device was not intrusive.

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Correlation of Structural and Functional Changes in Ocular Hypertension and Early Glaucoma

QJM ◽

10.1093/qjmed/hcaa058.019 ◽

2020 ◽

Vol 113 (Supplement_1) ◽

Author(s):

W O Noureldin ◽

H M Ebiary ◽

R G Zaki

Keyword(s):

Ocular Hypertension ◽

Open Angle Glaucoma ◽

Automated Perimetry ◽

Fiber Layer ◽

Temporal Area ◽

Early Glaucoma ◽

Functional Changes ◽

Rnfl Thickness ◽

Group I

Abstract Purpose To estimate the link between the thickness of retinal nerve fiber layer (RNFL); utilizing optical coherence tomography (OCT) and corresponding retinal sensitivity changes; utilizing visual field (VF) perimetry, in cases of ocular hypertension and early glaucoma. Methods Thirty patients (60 eyes) were gathered for this prospective, cross-sectional study. They were categorized into two groups. Group I comprised 30 eyes (15 patients) having ocular hypertension. Group II comprised 30 eyes (15 patients) early recognized as primary open angle glaucoma. Each patient underwent a thorough ophthalmologic examination, OCT for RNFL thickness estimation using quick RNFL thickness protocol and VF testing using automated perimetry (G2 program, central 30–2 threshold protocol). Pearson’s correlation was premediated between thickness of RNFL and VF indices. Results Significant connections between the thickness of temporal area of RNFL and mean sensitivity (MS), mean defect (MD) and loss of variance (LV) indices of VF (r = 0.533, -0.431, -0.388; P < 0.01, respectively) were noticed in patients having ocular hypertension. Additionally, a significant link between the thickness of the temporal area of RNFL and MS index of VF (0.441; P < 0.05) was noticed in patients with early POAG. Otherwise, there were no significant links between indices of VF and other areas of RNFL thickness in both groups. Conclusion Average RNFL thickness is certifiably not a dependable index for early determination of glaucoma or for the follow-up of ocular hypertension and POAG. Segmental RNFL thickness (especially temporal) appears to be a more dependable index. Profound structural modification with OCT test comprises an imperative sign of early utilitarian changes, regardless of whether they are not yet recognized with perimetry. The MS index of VF is by all accounts sensitive for the follow-up of ocular hypertension.

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Long-term follow-up of baseline learning and fatigue effects in the automated perimetry of glaucoma and ocular hypertensive patients

Acta Ophthalmologica ◽

10.1111/j.1755-3768.1991.tb02713.x ◽

2009 ◽

Vol 69 (2) ◽

pp. 210-216 ◽

Cited By ~ 36

Author(s):

J. M. Wild ◽

A. E. T. Searle ◽

M. Dengler-Harles ◽

E. C. O'Neill

Keyword(s):

Automated Perimetry ◽

Hypertensive Patients ◽

Long Term Follow Up

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Multifocal Electroretinogram in Hydroxychloroquine-related Macular Toxicity

Asian Journal of Ophthalmology ◽

10.35119/asjoo.v12i4.324 ◽

1970 ◽

Vol 12 (4) ◽

pp. 224-228

Author(s):

Parveen Sen ◽

Priya Ravi ◽

Rupak Roy

Keyword(s):

Rheumatoid Arthritis ◽

Visual Acuity ◽

Colour Vision ◽

Multifocal Electroretinogram ◽

Retinal Toxicity ◽

The Other ◽

Automated Perimetry ◽

Full Field

Prolonged use of hydroxychloroquine is common in patients with rheumatoid arthritis. Retinal toxicity due to hydroxychloroquine is known, and is monitored by investigations such as visual acuity, Amsler chart, colour vision, automated perimetry, full-field electroretinogram, and electrooculogram. Multifocal electroretinogram can suggest macular toxicity due to hydroxychloroquine even when the other investigations have normal results. Hence, multifocal electroretinogram has a role in the screening and follow-up of patients with suspected hydroxychloroquine toxicity.

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Applying a New Automated Perimetry Pattern Based on the Stimulus Distribution of the Multifocal ERG to Improve Structure-Function Investigation in Glaucoma

Journal of Ophthalmology ◽

10.1155/2017/8780934 ◽

2017 ◽

Vol 2017 ◽

pp. 1-11 ◽

Cited By ~ 1

Author(s):

Lívia M. Brandão ◽

Matthias Monhart ◽

Andreas Schötzau ◽

Anna A. Ledolter ◽

Anja M. Palmowski-Wolfe

Keyword(s):

Optical Coherence Tomography ◽

Structure Function ◽

Automated Perimetry ◽

Optical Coherence ◽

Fiber Layer ◽

Rnfl Thickness ◽

Significant Difference ◽

Retinal Structure ◽

One Year

Purpose. To validate a new automated perimetry pattern (mf103 pattern) for the investigation of retinal structure-function relationships in glaucoma in comparison to the standard G2 pattern and to relate either field’s performance to optical coherence tomography (OCT). Methods. Automated perimetry data from the mfERG103 pattern were compared with the standard G2 pattern in glaucoma patients (18) and controls (15). The results of both (mean defect (MD) and mean sensitivity (MS)) were compared with optical coherence tomography (OCT): retinal nerve fiber layer (RNFL) thickness, macular thickness (mT), and ganglion cell analysis (GCIPL). Nine patients were followed up after one year. Results. G2 pattern and mf103 pattern did not differ significantly in MD or MS. The mf103 pattern associated significantly with more RNFL sectors in both MD and MS (p<0.01 and p<0.05, resp.). GCIPL thickness was not significantly associated with either SAP protocols. Both protocols remained comparable after one-year follow-up. Conclusions. G2 and mf103 pattern can both differentiate patients from controls with no significant difference in performance. RNFL thickness defects correlated better with mf103 than G2 with POAG. The mfERG-103 perimetry pattern can be used to establish structure-function correlations in glaucoma and may enable a more direct comparison with objective electrophysiological data.

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Comparing the efficacy of trabeculectomy and XEN gel microstent implantation for the treatment of primary open-angle glaucoma: a retrospective monocentric comparative cohort study

Scientific Reports ◽

10.1038/s41598-020-76551-y ◽

2020 ◽

Vol 10 (1) ◽

Cited By ~ 1

Author(s):

Theresa Theilig ◽

Matus Rehak ◽

Catharina Busch ◽

Caroline Bormann ◽

Marc Schargus ◽

...

Keyword(s):

Visual Field ◽

Open Angle Glaucoma ◽

Statistical Significance ◽

Field Testing ◽

Automated Perimetry ◽

Open Angle ◽

Comparable Group ◽

Comparative Cohort Study ◽

Visual Field Indices

Abstract The aim of this study was to compare the efficacy and safety profile of XEN microstent implantation with trabeculectomy (TET) in a comparable group of open-angle glaucoma cases in a retrospective, monocentric, single-surgeon setting. Each treatment group consisted of 100 eyes of 100 patients. At regular follow-up visits during the first 12 months after surgery, the following assessments were conducted and compared: intraocular pressure (IOP), number of IOP-lowering medications applied, best-corrected visual acuity (BCVA) and visual field testing. In both groups mean IOP was significantly reduced (p < 0.001). Mean IOP dropped from 24.8 ± 7.8 to 14.8 ± 4.0 mmHg in the TET and from 24.5 ± 6.7 to 16.6 ± 4.8 mmHg in the XEN group. The number of active compounds in the prescribed medication dropped from 3.3 ± 1.2 to 1.3 ± 1.4 in the TET and from 3.0 ± 1.1 to 1.4 ± 1.5 in the XEN group. BCVA and mean defect of static automated perimetry did not show a change of statistical significance in either group. Complications were more frequent after TET (p = 0.005) while postoperative needling was more frequent in the XEN group (p = 0.021). TET and XEN led to a significant reduction of IOP and IOP-lowering medication, while BCVA and visual field indices remained mostly unaltered over a 12-month postsurgical follow-up.

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Transient Peripapillary Retinoschisis in Glaucomatous Eyes

Journal of Ophthalmology ◽

10.1155/2017/1536030 ◽

2017 ◽

Vol 2017 ◽

pp. 1-7 ◽

Cited By ~ 2

Author(s):

Josine van der Schoot ◽

Koenraad A. Vermeer ◽

Hans G. Lemij

Keyword(s):

Imaging Techniques ◽

Scanning Laser ◽

Automated Perimetry ◽

Standard Automated Perimetry ◽

Fiber Layer ◽

Laser Polarimetry ◽

Laser Tomography ◽

Healthy Eyes ◽

Sd Oct

Purpose. To investigate transient focal microcystic retinoschisis in glaucomatous eyes in images obtained with several imaging techniques used in daily glaucoma care.Methods. Images of 117 glaucoma patients and 91 healthy subjects participating in a large prospective follow-up study into glaucoma imaging were reviewed. Participants were measured with spectral domain optical coherence tomography (SD-OCT), scanning laser polarimetry (SLP), scanning laser tomography (SLT), and standard automated perimetry (SAP). The presence of a focal retinoschisis in SD-OCT was observed and correlated to SLP, SLT, and SAP measurements, both cross-sectionally and longitudinally.Results. Seven out of 117 glaucoma patients showed a transient, localised, peripapillary, heterogeneous microcystic schisis of the retinal nerve fiber layer (RNFL) and sometimes other retinal layers as well in SD-OCT. None of the healthy eyes showed this phenomenon nor did any of the other imaging techniques display it as detailed and consistently as did the SD-OCT. SAP showed a temporarily decreased focal retinal sensitivity during the retinoschisis and we found no signs of glaucomatous progression related to the retinoschisis.Conclusions. Transient microcystic retinoschisis appears to be associated with glaucomatous wedge defects in the RNFL. It was best observed with SD-OCT and it was absent in healthy eyes. We found no evidence that the retinoschisis predicted glaucomatous progression.

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Optical coherence tomography versus automated perimetry for follow-up of optic neuritis

Acta Ophthalmologica Scandinavica ◽

10.1111/j.1600-0420.2006.00724.x ◽

2006 ◽

Vol 84 (6) ◽

pp. 790-794 ◽

Cited By ~ 63

Author(s):

Susana Noval ◽

Inés Contreras ◽

Gema Rebolleda ◽

Francisco J. Muñoz-Negrete

Keyword(s):

Optical Coherence Tomography ◽

Optic Neuritis ◽

Automated Perimetry ◽

Optical Coherence

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Complications of Intra-Arterial tPA for Iatrogenic Branch Retinal Artery Occlusion: A Case Report through Multimodal Imaging and Literature Review

Medicina ◽

10.3390/medicina57090963 ◽

2021 ◽

Vol 57 (9) ◽

pp. 963

Author(s):

Katherine Dalzotto ◽

Paige Richards ◽

Tyler D. Boulter ◽

Marilyn Kay ◽

Mihai Mititelu

Keyword(s):

Visual Field ◽

Multimodal Imaging ◽

Retinal Artery Occlusion ◽

Artery Occlusion ◽

Fundus Photography ◽

Automated Perimetry ◽

Branch Retinal Artery Occlusion ◽

Retinal Artery ◽

Sd Oct

Background and Objectives: To document, through multimodal imaging, the post-procedural clinical course and visual outcome of a patient who received intra-arterial tissue plasminogen activator (tPA) for acute iatrogenic branch retinal artery occlusion (BRAO), and to review the literature and guidelines regarding the use of tPA for retinal arterial occlusions. Methods: A 28-year-old female patient who sustained an iatrogenic BRAO and subsequently received intra-arterial tPA was followed through her post-interventional course of 3 months with serial exams and multimodal imaging, including color fundus photography, visual field testing, spectral domain optical coherence tomography (SD-OCT), and OCT angiography (OCT-A). Results: A patient with history of left internal cerebral artery (ICA) aneurysm and baseline visual acuity (VA) of 20/20 developed an acutely symptomatic BRAO after undergoing a neuroendovascular procedure and was acutely treated with tPA through the left ophthalmic artery. At two weeks follow-up, a central posterior pole hemorrhage was noted although VA was preserved. A superior altitudinal defect was shown on automated perimetry. VA dropped to 20/50 at 7 weeks follow-up and hyperreflective material deep to the attachment between the posterior hyaloid and the internal limiting membrane (ILM) consistent with hemorrhage was noted on SD-OCT. At 11 weeks follow-up, VA returned to 20/20, SD-OCT revealed a membrane bridging the foveal depression, OCT-A showed decreased vascularity in the inferior macula, and the visual field defect was stable by automated perimetry. Conclusions: Intraocular hemorrhage is a possible complication of intra-arterial tPA administration for BRAO, and a careful analysis of risks, benefits, and goals of this procedure must be considered by both provider and patient before such intervention.

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