Diagnostic value of contrast enhancement in vascular Doppler ultrasound

Abstract The aim of the study was to investigate the diagnostic value of contrast-enhanced ultrasound (CEUS) in differentiating benign and malignant thyroid nodules. Thirty-five patients with morphologically proved thyroid nodules (17 malignant; 18 benign), underwent CEUS examination. Five enhancement patterns were evaluated: vascularisation, homogeneity, presence of peripheral rim type enhancement, wash-out rate of the contrast medium, and enhancement using microvascular imaging application. Time-intensity curves (TIC) were analysed in post-processing and defined as three types: slow versus rapid and stable versus rapid biphasic wash-out. Diagnostic value of the listed CEUS parameters was calculated. The results showed medium strength correlation between morphology (benign versus malignant nodule) and type of TIC curve rs = 0.38 (p = 0.021), as well as between mode of contrast enhancement rs = 0.39 (p = 0.022) and wash-out pattern rs =0.39 (p = 0.024). The overall pooled sensitivity of selected diagnostic parameters was 82%, specificity 57%, and accuracy 70%. Malignant nodules were characterised by iso- or hypovascular contrast enhancement and slow wash-out, while benign nodules showed hypervascular enhancement with rapid wash-out TIC curve and rim-like pattern. The CEUS patterns significantly differed between malignant and benign thyroid nodules with high diagnostic accuracy. Thus, CEUS has important clinical value as an additional tool to ultrasound and fine needle biopsy.

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Diagnostic Value of Color Doppler Ultrasound for Cutaneous Odontogenic Sinus Tract

Actas Dermo-Sifiliográficas (English Edition) ◽

10.1016/j.adengl.2015.07.005 ◽

2015 ◽

Vol 106 (8) ◽

pp. 678-680

Author(s):

C. Garrido Colmenero ◽

G. Blasco Morente ◽

J.M. Latorre Fuentes ◽

R. Ruiz Villaverde

Keyword(s):

Doppler Ultrasound ◽

Color Doppler ◽

Color Doppler Ultrasound ◽

Diagnostic Value ◽

Sinus Tract

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Diagnostic Value of Color Doppler Ultrasonography in Detecting Calcifications in Thyroid Nodules for Benign and Malignant Nodules

Journal of Medical Imaging and Health Informatics ◽

10.1166/jmihi.2020.3082 ◽

2020 ◽

Vol 10 (7) ◽

pp. 1621-1630

Author(s):

Xia Liu ◽

Defeng Chang ◽

Dan Xie

Keyword(s):

Thyroid Cancer ◽

Doppler Ultrasound ◽

Doppler Ultrasonography ◽

Thyroid Nodules ◽

Color Doppler ◽

Color Doppler Ultrasound ◽

Diagnostic Value ◽

Color Doppler Ultrasonography ◽

Benign Nodules ◽

Coarse Calcification

Objective: To investigate the diagnostic value of color Doppler ultrasonography in detecting calcifications in thyroid nodules for benign and malignant thyroid nodules. Methods: This study selects 108 patients with thyroid nodules who underwent color Doppler ultrasonography at designated hospitals from June 2013 to June 2018 as study subjects, retrospectively analyzes their general patient data, preoperative color Doppler ultrasound data and postoperative pathological diagnosis results, and discusses the diagnostic value of calcification rate, calcification type and calcification characteristics for benign and malignant thyroid nodules. Results: The results show that preoperative color Doppler ultrasonography found 112 thyroid nodules in 108 patients, including 72 benign nodules and 40 malignant nodules; pathological analysis confirmed 124 thyroid nodules, including 78 benign nodules and 46 malignant nodules; the diagnostic coincidence rate of color Doppler ultrasound is 90.32% (112/124), the misdiagnosis rate is 9.68% (12/124), the specificity is 86.94%, and the sensitivity is 81.27%; in these 112 thyroid nodules, 89 nodules were calcified accounting for 79.46%; in 72 benign nodules, 13 nodules were calcified accounting for 18.06%; in 40 malignant nodules, 17 were calcified accounting for 42.50%; the calcification of malignant nodules was significantly higher than that of benign nodules; in 72 benign nodules, 6 cases is coarse calcification accounting for 8.33%, 3 cases is cyclic calcification accounting for 4.16%, and cyclic and coarse calcification are only 23.46% sensitive to thyroid cancer; in 40 malignant nodules, 3 cases is coarse calcification accounting for 7.5%, and 2 cases is cyclic calcification accounting for 5.00%. Conclusions: According to the analysis, the calcification in thyroid nodules has relatively high sensitivity and specificity for the diagnosis of benign and malignant nodules and it can be used as a specific index for screening thyroid cancer.

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Color Doppler Ultrasonography Applied to Infertile Patients with Chronic Salpingitis and Mycoplasma Infection

Journal of Medical Imaging and Health Informatics ◽

10.1166/jmihi.2019.2641 ◽

2019 ◽

Vol 9 (2) ◽

pp. 329-333

Author(s):

Ting Sun ◽

Rui Ma ◽

Hongjun Zhu ◽

Lisha Wu

Keyword(s):

Doppler Ultrasound ◽

Color Doppler ◽

Color Doppler Ultrasound ◽

Diagnostic Value ◽

Mycoplasma Infection ◽

Ultrasound Guided ◽

X Ray ◽

Tubal Patency ◽

Single Side ◽

Infertile Patients

Objective: To investigate the diagnostic value of color Doppler ultrasonography applied to infertile patients with chronic salpingitis and mycoplasma infection. Methods: 116 infertile patients with chronic salpingitis and mycoplasma infection were selected in this investigation. After these patients were admitted to hospital, they all underwent color Doppler ultrasound guided hysterosalpingogram and X-ray hysterosalpingography, in order to make definitive diagnoses, and the X-ray hysterosalpingography was considered as the gold standard. The diagnostic value and rates of adverse reaction between color Doppler ultrasound guided hysterosalpingogram and X-ray hysterosalpingography were evaluated. Results: A total of 116 patients with chronic salpingitis and mycoplasma infection received color Doppler ultrasound guided hysterosalpingogram and X-ray hysterosalpingography. Diagnostic coincidence rates were equal, and no statistical difference could be observed (P > 0.05), with respect to the tubal patency in double sides, tubal obstruction in double sides, tubal patency in single side, and tubal obstruction in single side. When concerning adverse reactions, the incidence rates of allergy and colporrhagia between two groups were statistically significantly different (P = 0.025 and P = 0.040, respectively). In addition, the total incidence rate of adverse reactions was also statistically significant different (P = 0.003). Conclusion: The color Doppler ultrasound aided hysterosalpingogram could make a diagnosis intuitively and clearly for patients with chronic salpingitis and mycoplasma infection, and can be used as the preferred method for diagnosing tubal infertility.

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