Reverse Pharmacology: A Tool for Drug Discovery from Traditional Medicine

Author(s):  
V. Suba
Author(s):  
Saifur R. Khan ◽  
Dana Al Rijjal ◽  
Anthony Piro ◽  
Michael B. Wheeler

2017 ◽  
pp. 425-458
Author(s):  
Rajesh K. Joshi

The word phytopharmaceutical deals with a complex mixture of compounds derived from the plant source that is used as a medicine or drug. Primitive human societies have been depending on plants and plant products for various remedies. Several plants in the different forms have been reported in traditional medicine and to find a rational for the treatment of various diseases than to isolated single compounds. Many of the single compounds isolated from the plant origin are effectively used in the medicine. The search of natural products in drug discovery has been greatly enhanced in the last few years. The impetus to use phytopharmaceutical agents for the treatment of disease, most of the plant based drugs are quite safe and have lesser adverse effects and are claimed that it works as synergistic effects.


2021 ◽  
pp. 281-297
Author(s):  
Antara Banerjee ◽  
M.S. Pavane ◽  
L. Husaina Banu ◽  
A. Sai Rishika Gopikar ◽  
K. Roshini Elizabeth ◽  
...  

2014 ◽  
Vol 9 (2) ◽  
pp. 1934578X1400900
Author(s):  
Ambarish Mukherjee ◽  
Mousumi Banerjee ◽  
Vivekananda Mandal ◽  
Amritesh C. Shukla ◽  
Subhash C. Mandal

Ayurveda has been the main guiding force in drug discovery from traditional medicine. In concept, this system is rooted in folk or ethnomedicine and in practice it shows further refinement and development in accordance with local traditions. Isolation of active principles from crude drugs, their pharmacological evaluation, therapeutic proving and clinical application resulted in the genesis of modern or so called allopathic medicine. To keep the opportunity alive for further development in traditional as well as modern medicines, it is necessary to have an uninterrupted connection with ethnomedicine. Since the practice of ethnomedicine is based on the age-long indigenous knowledge which has been orally transmitted through generations and sustained in traditions there is an urgent need to document such knowledge. The ongoing strategies adopted in India to document the precious traditional knowledge and conserve medicinal plants are discussed in this communication. India with her rich plant wealth and traditional knowledge about the medicinal use of plants has tremendous scope to provide leadership in ensuring human health and longevity.


2010 ◽  
Vol 31 (2) ◽  
pp. 60
Author(s):  
Kristin I Miller ◽  
Shane D Ingrey ◽  
Alfonsus Alvin ◽  
Man Yuen Daniel Sze ◽  
Basil D Roufogalis ◽  
...  

Traditional medicine continues to play an essential role in the healthcare systems of many cultures. In some Asian and African countries up to 80% of the population depend on these ancient and culturally based medicinal practices for their primary healthcare needs. Plants and their derived natural products are frequently employed as traditional medicine and such plants are viewed as attractive targets for the discovery of novel therapeutic agents in natural product investigations. A variety of useful drugs has been discovered following the investigation of traditional herbs, such as morphine (analgesic), digitoxin (cariotonic) and ephedrine (sympathomimetic). These ethnopharmacology approaches to drug discovery are based on the premise that plants used as traditional medicines have shown some form of bioactivity and have the increased likelihood of containing bioactive compounds in comparison to plants selected at random. Three systems of traditional medicine that are relevant to Australian drug discovery researchers include the Chinese, Australian Aboriginal and Indonesian systems.


2011 ◽  
Vol 135 (2) ◽  
pp. 590-593 ◽  
Author(s):  
Eric S.J. Harris ◽  
Sean D. Erickson ◽  
Andrew N. Tolopko ◽  
Shugeng Cao ◽  
Jane A. Craycroft ◽  
...  

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