scholarly journals A Perspective on the Phytopharmaceuticals Responsible for the Therapeutic Applications

2017 ◽  
pp. 425-458
Author(s):  
Rajesh K. Joshi
Keyword(s):  
Natural Products ◽  
Drug Discovery ◽  
Adverse Effects ◽  
Traditional Medicine ◽  
Synergistic Effects ◽  
Complex Mixture ◽  
Plant Origin ◽  
Plant Source ◽  
Plant Products ◽  
Therapeutic Applications

The word phytopharmaceutical deals with a complex mixture of compounds derived from the plant source that is used as a medicine or drug. Primitive human societies have been depending on plants and plant products for various remedies. Several plants in the different forms have been reported in traditional medicine and to find a rational for the treatment of various diseases than to isolated single compounds. Many of the single compounds isolated from the plant origin are effectively used in the medicine. The search of natural products in drug discovery has been greatly enhanced in the last few years. The impetus to use phytopharmaceutical agents for the treatment of disease, most of the plant based drugs are quite safe and have lesser adverse effects and are claimed that it works as synergistic effects.

A Perspective on the Phytopharmaceuticals Responsible for the Therapeutic Applications

2016 ◽  
pp. 229-262 ◽  
Author(s):  
Rajesh K. Joshi
Keyword(s):  
Natural Products ◽  
Drug Discovery ◽  
Adverse Effects ◽  
Traditional Medicine ◽  
Synergistic Effects ◽  
Complex Mixture ◽  
Plant Origin ◽  
Plant Source ◽  
Plant Products ◽  
Therapeutic Applications

The word phytopharmaceutical deals with a complex mixture of compounds derived from the plant source that is used as a medicine or drug. Primitive human societies have been depending on plants and plant products for various remedies. Several plants in the different forms have been reported in traditional medicine and to find a rational for the treatment of various diseases than to isolated single compounds. Many of the single compounds isolated from the plant origin are effectively used in the medicine. The search of natural products in drug discovery has been greatly enhanced in the last few years. The impetus to use phytopharmaceutical agents for the treatment of disease, most of the plant based drugs are quite safe and have lesser adverse effects and are claimed that it works as synergistic effects.

scholarly journals Drug interactions between herbal medicines and oral contraceptives

2021 ◽  
Vol 10 (13) ◽  
pp. e372101321331
Author(s):  
Daniella Jordão Valmiro ◽  
Lucas Moyses Pinto ◽  
Lucas Nascimento Barbosa ◽  
Luiza Beatriz Carvalho de Araújo ◽  
Rodrigo Vieira Gonzaga
Keyword(s):  
Adverse Effects ◽  
Drug Interactions ◽  
Oral Contraceptives ◽  
Synergistic Effects ◽  
Herbal Medicines ◽  
Chemical Compounds ◽  
Clinical Effects ◽  
Plant Origin ◽  
Saw Palmetto ◽  
Kava Kava

The use of herbal medicines has grown considerably in recent years, due to the erroneous thought that products of plant origin are harmless, and therefore do not cause adverse effects or have drug interactions. The use of these drugs with oral contraceptives can bring risks to patients. The potential negative clinical effects that can be caused by these drug interactions must be emphasized to prevent risks and ensure the effectiveness of this contraceptive method that is one of the most used by women seeking to prevent pregnancy. The users of herbal medicines usually believe that herbal medicine is a therapeutic alternative free of adverse effects and/or incapable of causing drug interactions, but herbal medicines are composed of several chemical compounds, which, in turn, may be responsible for antagonistic and/or synergistic effects with other drugs. The main interactions that can occur with contraceptives are with popularly used herbal medicines such as licorice, alfalfa, cannabis, cimicifuga, St. John's wort, ginseng, kava-kava, saw palmetto, sene, and soy. The herbal medicines have several chemical compounds, among which we highlight the secondary metabolites, responsible for the pharmacological actions and mechanism of action of drug interactions, which are often similar in plants that have in their composition the same metabolites, as in the case of saponins and isoflavones that reduce the speed of biotransformation of oral contraceptives.

Nanotechnology based herbal formulations: A survey of recent patents, advancements and transformative headways

2021 ◽  
Vol 15 ◽  
Author(s):  
Anureet Kaur ◽  
Lakhvir Kaur ◽  
Gurjeet Singh ◽  
RK Dhawan ◽  
Ayushi Mahajan
Keyword(s):  
Side Effects ◽  
Herbal Medicine ◽  
Adverse Effects ◽  
Traditional Medicine ◽  
Synergistic Effects ◽  
Complete Information ◽  
Review Article ◽  
Innovative Technology ◽  
Herbal Drugs ◽  
Herbal Formulations

: Nanotechnology in association with the herbal medicine can lead to enhanced therapeutic and diminished adverse effects of medication. In turn, it can lead to synergistic effects of administered compound overcoming its demerits. Now-a-days, the trend of herbal compounds to treat even a small illness is gaining momentum. Gone are the days when the ineffectiveness of a compound was impossible to be dealt with. Nevertheless, in this competitive era of science and innovative technology, it has become possible to maximize the usefulness of ineffective yet potent herbal compounds. The demand of herbal compounds is getting amplified because of their ability to treat myriad of diseases including COVID-19, showing less side effects. The merger of nanotechnology with traditional medicine augments the potential of herbal drugs for devastating dangerous and chronic diseases like cancer. In this review article, we have tried to assimilate the complete information regarding the use of different nanocarriers to overcome the drawbacks of herbal compounds. In addition, all the recent advancements in the herbal field as well as the future exploration to be emphasized have been discussed.

scholarly journals Application of Amino Acids in the Structural Modification of Natural Products: A Review

2021 ◽  
Vol 9 ◽  
Author(s):  
Qian Xu ◽  
Hao Deng ◽  
Xiaoting Li ◽  
Zhe-Shan Quan
Keyword(s):  
Amino Acids ◽  
Natural Products ◽  
Drug Discovery ◽  
Adverse Effects ◽  
Theoretical Basis ◽  
Structural Modification ◽  
Poor Solubility ◽  
Wide Range ◽  
The Future ◽  
Low Activity

Natural products and their derivatives are important sources for drug discovery; however, they usually have poor solubility and low activity and require structural modification. Amino acids are highly soluble in water and have a wide range of activities. The introduction of amino acids into natural products is expected to improve the performance of these products and minimize their adverse effects. Therefore, this review summarizes the application of amino acids in the structural modification of natural products and provides a theoretical basis for the structural modification of natural products in the future. The articles were divided into six types based on the backbone structures of the natural products, and the related applications of amino acids in the structural modification of natural products were discussed in detail.

scholarly journals Drug Discovery form Natural Products and Traditional Medicine, Strategy and Applications

2018 ◽  
Vol WCP2018 (0) ◽  
pp. SY69-4
Author(s):  
Guanhua Du ◽  
Lianhua Fang ◽  
Yuehua Wang ◽  
Li Zhang ◽  
Yang Lv ◽  
...  
Keyword(s):  
Natural Products ◽  
Drug Discovery ◽  
Traditional Medicine

scholarly journals Pharmacological, medicinal and toxicological properties of lavender essential oil: A review

2021 ◽  
Vol 10 (5) ◽  
pp. e23310514933
Author(s):  
Gabriel Fernando Esteves Cardia ◽  
Francielli Maria de Souza Silva-Comar ◽  
Edvalkia Magna Teobaldo da Rocha ◽  
Saulo Euclides Silva-Filho ◽  
Mayara Zagotto ◽  
...  
Keyword(s):  
Natural Products ◽  
Medicinal Plants ◽  
Essential Oil ◽  
Adverse Effects ◽  
Essential Oils ◽  
Traditional Medicine ◽  
New Drugs ◽  
Pharmacological Properties ◽  
New Research ◽  
Therapeutic Possibilities

The natural products extracted from plants are part of traditional medicine and are also therapeutic possibilities for treating many diseases. Recently, its use in the development of new drugs has shown much visibility for its efficiency and few adverse effects. Essential oils extracted from medicinal plants are indicated to treat numerous diseases due to their antimicrobial, antiviral, antimutagenic, anticancer, antioxidant, anti-inflammatory, immunomodulatory, and antiprotozoal properties. Among essential oils, lavender essential oil stands out for having several important pharmacological properties. This review detailed the main studies on essential oils from different species of lavender and obtained a valuable collection on all their pharmacological, medicinal and toxicological potential. In this context, we evaluated lavender essential oil as a promising substance that can help treat several diseases. We provide some evidence and an overview of the potential therapeutic effect of lavender essential oil to guide new research.

Sign in / Sign up

Export Citation Format

Share Document