Medicinal Plants in Uganda as Potential Therapeutics against Neurological Disorders

A total of 73 medicinal plants belonging to 44 families of angiosperms were found to be used in the healing practice of 36 types of diseases including diabetics, heart problem, and neurological disorders by Koch Rajbangshi people of North Salmara sub-division of Bongaigaon district, Assam. More use of leaf was found in disease treatment than other parts of plant. Among the plants species 49 were common in occurrence, 19 species less common and 5 species viz., Aristolochia indica L., Asparagus recemosus Willd., Cissus quadrangularis L., Garcinia morella (Gaertn.) Desv and Rauvolfia serpentina Benth. were in rare category in the study area.DOI: http://dx.doi.org/10.3126/on.v11i1.8243 Our Nature Vol.11(1) 2013: 45-53

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Medicinal Plants: A Natural Chaperones Source for Treating Neurological Disorders

Protein and Peptide Letters ◽

10.2174/092986609787316234 ◽

2009 ◽

Vol 16 (2) ◽

pp. 116-120 ◽

Cited By ~ 5

Author(s):

Bernd Kastenholz ◽

David Garfin

Keyword(s):

Medicinal Plants ◽

Neurological Disorders

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Inhibitors of Endocannabinoid Degradation: Potential Therapeutics for Neurological Disorders

Angewandte Chemie International Edition ◽

10.1002/anie.200301641 ◽

2003 ◽

Vol 42 (26) ◽

pp. 2938-2941 ◽

Cited By ~ 3

Author(s):

Michaela Wendeler ◽

Thomas Kolter

Keyword(s):

Neurological Disorders ◽

Potential Therapeutics

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Selective targeting of MAPK family kinases JNK over p38 by rationally designed peptides as potential therapeutics for neurological disorders and epilepsy

Molecular BioSystems ◽

10.1039/c6mb00297h ◽

2016 ◽

Vol 12 (8) ◽

pp. 2532-2540 ◽

Cited By ~ 15

Author(s):

Zhi-Hong Zhuo ◽

Yi-Zhen Sun ◽

Pei-Na Jin ◽

Feng-Yan Li ◽

Yi-Le Zhang ◽

...

Keyword(s):

Neurological Disorders ◽

Selective Targeting ◽

Systematic Strategy ◽

Epilepsy Therapy ◽

Potential Therapeutics

A systematic strategy is described to optimize peptide selectivity between the MAPK family kinases JNK and p38 for epilepsy therapy.

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The Confrontation between Ethnopharmacology and Pharmacological Tests of Medicinal Plants Associated with Mental and Neurological Disorders

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2018/7686913 ◽

2018 ◽

Vol 2018 ◽

pp. 1-27

Author(s):

Giovanna Felipe Cavalcante e Costa ◽

Hisao Nishijo ◽

Leonardo Ferreira Caixeta ◽

Tales Alexandre Aversi-Ferreira

Keyword(s):

Nervous System ◽

Side Effects ◽

Medicinal Plants ◽

Neurological Disorders ◽

Scientific Literature ◽

High Rate ◽

Therapeutic Effects ◽

Pharmacological Tests ◽

Pharmacological Studies ◽

Discrepancy Rate

For neurological disorders, pharmacological tests have shown promising results in the reduction of side effects when using plants with known therapeutic effects in the treatment of some types of dementia. Therefore, the goals of this study are to gather data about the major medicinal plants used in the nervous system as described in ethnopharmacological surveys from South America and Brazil and to compare this data with the results from pharmacological tests on the active principles of those same plants found in the scientific literature. After collecting the data about each plant, their respective popular indication was compared with the results found through pharmacological tests. The discrepancy rate between the effects observed by ethnopharmacological and pharmacological methods in this study is greater than 50%. In conclusion, despite the importance of ethnopharmacological data, it is important to make comparisons with pharmacological tests for the same plants, since the pharmacological studies, although few, have shown a high rate of discrepancy in the results.

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