Preparation of Ultrasmall Gold Nanoparticles for Nuclear-Based Gene Delivery

2021 ◽  
pp. 1-9
Author(s):  
Zhihuan Liao ◽  
Shuaidong Huo ◽  
Xing-Jie Liang
Keyword(s):  
Gold Nanoparticles ◽  
Gene Delivery

Preparation of Cationic Gold Nanoparticles for Gene Delivery

2008 ◽  
Vol 2 (2) ◽  
pp. 152-156 ◽  
Author(s):  
Guoping Chen ◽  
Michiaki Takezawa ◽  
Naoki Kawazoe ◽  
Tetsuya Tateishi
Keyword(s):  
Gold Nanoparticles ◽  
Gene Delivery ◽  
Cationic Gold

scholarly journals Chitosan-gold nanoparticles mediated gene delivery of c-myb facilitates osseointegration of dental implants in ovariectomized rat

2018 ◽  
Vol 46 (sup3) ◽  
pp. S807-S817 ◽  
Author(s):  
Jyoti Shrestha Takanche ◽  
Ji-Eun Kim ◽  
Jeong-Seok Kim ◽  
Min-Ho Lee ◽  
Jae-Gyu Jeon ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Gene Delivery ◽  
Dental Implants ◽  
Ovariectomized Rat

Zwitterion-functionalized dendrimer-entrapped gold nanoparticles for serum-enhanced gene delivery to inhibit cancer cell metastasis

2019 ◽  
Vol 99 ◽  
pp. 320-329 ◽  
Author(s):  
Zhijuan Xiong ◽  
Carla S. Alves ◽  
Jianhua Wang ◽  
Aijun Li ◽  
Jinyuan Liu ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Gene Delivery ◽  
Cancer Cell ◽  
Cell Metastasis

Di-Sulfide Linked Polyethylenimine Coated Gold Nanoparticles as a Non-Viral Gene Delivery Agent in NIH-3T3 Mouse Embryonic Fibroblast

2015 ◽  
Vol 15 (10) ◽  
pp. 7895-7899 ◽  
Author(s):  
Saji Uthaman ◽  
Myeong Ju Moon ◽  
Duhwan Lee ◽  
Won Jong Kim ◽  
In-Kyu Park
Keyword(s):  
Gold Nanoparticles ◽  
Gene Delivery ◽  
Fluorescent Microscopy ◽  
Weight Ratio ◽  
Mouse Embryonic Fibroblast ◽  
Luciferase Assay ◽  
Viral Gene ◽  
Hydrodynamic Diameter ◽  
Tem Analysis ◽  
Average Size

Di-sulfide linked polyethylenimine coated gold nanoparticles (ssPEI-GNPs) of 20 nm size was prepared in order to deliver the genes to target site. DLS and TEM analysis demonstrated that the GNPs have average size of 13 nm in diameter. Upon coating the GNPs with ssPEI in the weight ratio of 1:3, the average hydrodynamic diameter of the ssPEI-GNPs was found to 19 ± 1.14 nm and a zeta potential value 41 ± 1.23 mV was observed. TEM analysis of ssPEI-GNPs demonstrated that the nanoparticles have spherical morphology. Thermogravemetric analysis of the prepared ssPEI-GNPs showed that the estimated composition of the ssPEI coated over the GNPs was approximately 5% (w/w). Gene expression capabilities of the nanoparticles were confirmed by fluorescent microscopy and luciferase assay, which demonstrated the transgene delivery capability of the ssPEI-GNPs. These results demonstrate that ssPEI-GNPs could be used as gene delivery agent.

Transportation and fate of gold nanoparticles in oilseed rape

RSC Advances ◽  
2015 ◽  
Vol 5 (90) ◽  
pp. 73827-73833 ◽  
Author(s):  
Jichao Zhang ◽  
Liang Pan ◽  
Min Lv ◽  
Ali Aldalbahi ◽  
Tian Xie ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Gene Delivery ◽  
Oilseed Rape ◽  
Potential Application ◽  
Rape Seedlings

In this work, we demonstrate the mild effect of AuNPs on the growth of oilseed rape seedlings and suggest their potential application as vehicles for gene delivery in plants.

The forthcoming applications of gold nanoparticles in drug and gene delivery systems

2011 ◽  
Vol 149 (1) ◽  
pp. 65-71 ◽  
Author(s):  
Dakrong Pissuwan ◽  
Takuro Niidome ◽  
Michael B. Cortie
Keyword(s):  
Gold Nanoparticles ◽  
Gene Delivery ◽  
Delivery Systems ◽  
Drug And Gene Delivery

scholarly journals Polymer functionalized gold nanoparticles as nonviral gene delivery reagents

2017 ◽  
Vol 19 (6-7) ◽  
pp. e2964 ◽  
Author(s):  
M. Mar Encabo-Berzosa ◽  
Maria Sancho-Albero ◽  
Victor Sebastian ◽  
Silvia Irusta ◽  
Manuel Arruebo ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Gene Delivery ◽  
Nonviral Gene Delivery ◽  
Functionalized Gold Nanoparticles

Antimicrobial peptide modification enhances the gene delivery and bactericidal efficiency of gold nanoparticles for accelerating diabetic wound healing

2018 ◽  
Vol 6 (10) ◽  
pp. 2757-2772 ◽  
Author(s):  
Song Wang ◽  
Chang Yan ◽  
Ximu Zhang ◽  
Dezhi Shi ◽  
Luxiang Chi ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Wound Healing ◽  
Gene Delivery ◽  
Bacterial Infection ◽  
Antimicrobial Peptide ◽  
Diabetic Wound ◽  
Peptide Modification ◽  
Diabetic Wound Healing ◽  
Bactericidal Efficiency ◽  
Impaired Angiogenesis

Impaired angiogenesis and bacterial infection have increasingly been implicated as the major causes of delayed diabetic wound healing.

Cationic modified gold nanoparticles show enhanced gene delivery in vitro

2016 ◽  
Vol 5 (5) ◽  
Author(s):  
Geraldine Genevive Lazarus ◽  
Moganavelli Singh
Keyword(s):  
Gene Therapy ◽  
Gold Nanoparticles ◽  
Gene Delivery ◽  
Therapeutic Agent ◽  
Cationic Polymer ◽  
Effective Drug ◽  
Innovative Strategies ◽  
Or Gene

AbstractGold nanoparticles (AuNPs) can be suitably engineered for applications in gene delivery, and as carriers of peptides and proteins. They present innovative strategies in gene therapy for the treatment of genetic as well as acquired diseases. Optimisation of AuNPs in binding and the eventual release of the therapeutic agent in a controlled manner are crucial steps in the pathway to effective drug or gene therapy. In this study, we propose the formulation of cationic polymer [chitosan (Chit) and poly-

Lipid-Coated Gold Nanoparticles Functionalized by Folic Acid as Gene Vectors for Targeted Gene Delivery in vitro and in vivo

ChemMedChem ◽  
2017 ◽  
Vol 12 (21) ◽  
pp. 1768-1775 ◽  
Author(s):  
Baoji Du ◽  
Xiaoxiao Gu ◽  
Xu Han ◽  
Guanyu Ding ◽  
Yuling Wang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Folic Acid ◽  
Gene Delivery ◽  
Targeted Gene Delivery ◽  
Gene Vectors
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