Nature-Inspired Metaheuristic Algorithms for Constraint Handling: Challenges, Issues, and Research Perspective

Author(s):  
Surabhi Kaul ◽  
Yogesh Kumar
2021 ◽  
Vol 11 (18) ◽  
pp. 8739
Author(s):  
José Saúl Muñoz-Reina ◽  
Miguel Gabriel Villarreal-Cervantes ◽  
Leonel Germán Corona-Ramírez

Currently, rehabilitation systems with closed kinematic chain mechanisms are low-cost alternatives for treatment and health care. In designing these systems, the dimensional synthesis is commonly stated as a constrained optimization problem to achieve repetitive rehabilitation movements, and metaheuristic algorithms for constrained problems are promising methods for searching solutions in the complex search space. The Constraint Handling Techniques (CHTs) in metaheuristic algorithms have different capacities to explore and exploit the search space. However, the study of the relationship in the CHT performance of the mechanism dimensional synthesis for rehabilitation systems has not been addressed, resulting in an important gap in the literature of such problems. In this paper, we present a comparative empirical study to investigate the influence of four CHTs (penalty function, feasibility rules, stochastic-ranking, and ϵ-constraint) on the performance of ten representative algorithms that have been reported in the literature for solving mechanism synthesis for rehabilitation (four-bar linkage, eight-bar linkage, and cam-linkage mechanisms). The study involves analysis of the overall performance, six performance metrics, and evaluation of the obtained mechanism. This identified that feasibility rules usually led to efficient optimization for most analyzed algorithms and presented more consistency of the obtained results in these kinds of problems.


1989 ◽  
Vol 34 (1) ◽  
pp. 87-87
Author(s):  
No authorship indicated

Author(s):  
Dr. Sushma Patil ◽  
Dr. Vikrant Patil

Thyroid disorders are common worldwide. Thyroid dysfunction, both hypo- and hyperthyroidism may increase the risk of cardiovascular disorders. Current thyroid function tests may have limitations since they only measure the total or free T4 and/or T3 and TSH serum concentrations in peripheral blood and not the effect of T4 or T3 serum on different specific target tissues. Several comorbid conditions can interfere with the absorption or increase the clearance of levothyroxine. Among patients treated with thyroid replacement, under or overmedicated may-be at risk for adverse health consequences. A wide range of drugs may interfere with levothyroxine absorption, metabolism, and action. Patients report a lack of well-being, despite reaching euthyroid reference range of TSH, with psychological distress. If we will consider Thyroid related conditions as a syndrome then research perspective at the pathophysiology, interrelation between symptoms and comorbidities will be much broader that can lead researchers to get insights of different pathways in which thyroid gland functioning can be perceived and dealt therapeutically. The deliberation of thyroid disorder as a syndrome can affluence our knowledge of correlating cofounders, action of thyroid hormones on target tissues, underlying cause and thyroid health.


2008 ◽  
Vol 2008 (1) ◽  
pp. 7-36 ◽  
Author(s):  
Rolf Elberfeld

In the 20th century the European sciences have tried in different ways to develop post-colonial forms of knowledge. Since the 1920s, under headings such as »intercultural«, »multicultural« and »transcultural«, discourses have arisen in the USA and in Europe in which, until the present, new perspectives and structures in the sciences have developed. The article offers, on one hand, a discourse analysis of these three headings until 1980 and makes clear by way of examples how complicated and deep the challenges are for knowledge discourses in Europe within the scope of the research perspective of »interculturality«.


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