Spontaneous DNA synthesis of blood lymphoid cells in premature newborn infants, in older premature infants and in full-term newborn infants

1974 ◽  
Vol 118 (3) ◽  
pp. 197-206 ◽  
Author(s):  
Gregor Prindull
1975 ◽  
Vol 86 (5) ◽  
pp. 773-778 ◽  
Author(s):  
Gregor Prindull ◽  
Brigitte Prindull ◽  
Arie Ron ◽  
Joseph M. Yoffey

1960 ◽  
Vol 15 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Juergen E. Thomas ◽  
Edward H. Lambert

Measurements of conduction velocity of the motor fibers of the ulnar nerve in the segment between the upper part of the arm and the wrist were made in 6 premature infants, 42 full-term newborn infants and 98 children up through the age of 14 years. In premature infants, 21 – 40 days before full term, values ranged from 18 to 22 meters per second with a mean of 21. Full-term newborn infants had velocities that ranged from 21 to 33 m.p.s., with a mean of 28. The values in the newborn were about one-half those of normal young adults, which range from 47 to 73 m.p.s. (mean, 60). By the age of 3 years almost all values were in the lower part of the adult range and, at 5 years, the velocities were not significantly different from those of the adult. These observations are in harmony with information about the diameter of nerve fibers during growth in man. The H-reflex could be elicited by stimulation of the ulnar nerve in almost every newborn infant. By the age of 1 year and thereafter it could rarely be elicited. Between the elbow and wrist, afferent fibers subserving this reflex conducted with a mean velocity of 30 m.p.s. Data on the action potential of the hypothenar muscles, residual latency of conduction in the ulnar nerve, latency of the H-reflex and conduction in the peroneal nerve in infants and children are compared with those on adults. Submitted on July 15, 1959


Blood ◽  
1963 ◽  
Vol 21 (6) ◽  
pp. 755-763 ◽  
Author(s):  
RUTH T. GROSS ◽  
ELEANOR A. R. SCHROEDER ◽  
SUSAN A. BROUNSTEIN

Abstract 1. The following aspects of energy metabolism have been compared in the erythrocytes of premature infants, full term newborn infants, and adults: levels of activity of the enzymes involved in the generation and utilization of ATP, and measurements of the content of ATP and of ADP. 2. The levels of activity of hexokinase, phosphoglyceric acid kinase and pyruvate kinase are significantly increased in the erythrocytes of premature and full term newborn infants compared to adults. 3. The level of activity of phosphofructokinase is significantly decreased in the erythrocytes of premature and full term newborn infants compared to adults. 4. In the erythrocytes of premature infants the content of ATP is significantly increased compared to both full term newborns and adults. The content of ADP is not increased. The percentage content of ADP is significantly below the values found in full term newborn infants and adults. 5. In the erythrocytes of full term newborn infants the content of both ATP and ADP is significantly greater than in adults. The ratio of ADP to the total amount of ATP plus ADP does not differ from the adult value.


PEDIATRICS ◽  
1971 ◽  
Vol 48 (6) ◽  
pp. 998-999
Author(s):  
S. H. Reisner ◽  
M. Cornblath ◽  
Ronald W. Gotlin

In the article by J. R. Humbert and R. W. Gotlin,1 the authors state that previous reports in which hypoglycemia was induced artificially with insulin demonstrated a variable growth hormone response. They then refer to the paper by Cornblath, et al.2 as reporting a failure to obtain a rise in growth hormone levels. This is incorrect as we found that insulin-induced hypoglycemia actually resulted in a very marked rise in growth hormone levels in both the full-term and premature infants tested.


PEDIATRICS ◽  
1985 ◽  
Vol 75 (3) ◽  
pp. 617-618
Author(s):  
CARLO CORCHIA ◽  
MARIA RUIU ◽  
MARCELLO ORZALESI

To the Editor.— Osborn et al1 have reported a positive association between breast-feeding and neonatal hyperbilirubinemia in full-term infants. To give further support to the findings of Osborn et al, we wish to report the results of two similar studies that have been completed in two different hospitals. The first study was carried out in the nursery of the Second School of Medicine of Naples.2 Rooming-in was practiced from 9 am to 12 pm, and during the day, breastfed babies were only offered a supplement of 5% dextrose in water when appropriate.


PEDIATRICS ◽  
1964 ◽  
Vol 33 (6) ◽  
pp. 999-999
Author(s):  
STANTON G. AXLINE ◽  
HAROLD J. SIMON

Studies on the clinical pharmacology of drugs in newborn infants have uncovered a problem of overdosage which may be more common than generally appreciated. Several medicaments are available only in a limited number of highly concentrated formulations. The requirements of premature and full-term newborn infants for very small total dosages necessitate very careful measurements of minute quantities of drug, and overdosage can readily occur. Specifically, Kanamycin is available in only two formulations for injection containing respectively 250 and 333 mg/ml. The dosage of this agent for newborn infants is approximately 8 mg/Kg of body weight 12 hourly.


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