Is the rise of the action potential of the ranvier node controlled by a paranodal organ?

1974 ◽  
Vol 61 (8) ◽  
pp. 369-370 ◽  
Author(s):  
H. M�ller-Mohnssen ◽  
A. Tippe ◽  
F. Hillenkamp ◽  
E. Uns�ld
Keyword(s):  
Action Potential ◽  
Ranvier Node

Effect of anodal and cathodal pulses applied during action potential at a single Ranvier node

1959 ◽  
Vol 197 (6) ◽  
pp. 1247-1254 ◽  
Author(s):  
Hiroshi Ooyama ◽  
Ernest B. Wright
Keyword(s):  
Action Potential ◽  
Refractory Period ◽  
Pulse Amplitude ◽  
Ranvier Node ◽  
Delayed Response ◽  
Positive Pulse ◽  
Applied Pulse ◽  
Single Ranvier Node

An anodal pulse applied during the falling phase of an action potential, if weak, produces a slight enhancement of negativity of the falling phase, but if increased in amplitude produces a split of the action potential into an early and "delayed" response and finally, complete abolition of the falling phase. If the pulse amplitude is increased still more after abolition, a second response is elicited. The latency to this second response following abolition is shorter than the latency to the delayed response, and further increase of the applied pulse amplitude cannot abolish this second response. To obtain abolition of the delayed response it is necessary to apply a considerably stronger anodal pulse near the peak of the spike than later during the falling phase. The reverse is true to obtain the second response. The anodal pulse sufficient to produce anode break excitation during the action potential and elicit the second response is ineffective applied to a resting node membrane. It is postulated that: a) due to an effect of the action potential itself the membrane is being actively depolarized during the early falling phase of the spike and b) the excitability of the node membrane is actually retained both during and following an action potential in the so-called refractory period but requires "resetting" by a positive pulse in order for re-excitation to take place.

scholarly journals Tuning of Ranvier node and internode properties in myelinated axons to adjust action potential timing

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Marc C. Ford ◽  
Olga Alexandrova ◽  
Lee Cossell ◽  
Annette Stange-Marten ◽  
James Sinclair ◽  
...  
Keyword(s):  
Action Potential ◽  
Ranvier Node ◽  
Myelinated Axons

How to sample the entire length of a single muscle fiber quick-frozen after electrical point stimulation for high resolution EM

1992 ◽  
Vol 50 (1) ◽  
pp. 776-777
Author(s):  
Joachim R. Sommer ◽  
Teresa High ◽  
Betty Scherer ◽  
Isaiah Taylor ◽  
Rashid Nassar
Keyword(s):  
Skeletal Muscle ◽  
High Resolution ◽  
Action Potential ◽  
Muscle Fiber ◽  
Freeze Fracture ◽  
Freeze Substitution ◽  
Electrical Field Stimulation ◽  
Skeletal Muscle Fiber ◽  
Freeze Dried ◽  
Quick Freezing

We have developed a model that allows the quick-freezing at known time intervals following electrical field stimulation of a single, intact frog skeletal muscle fiber isolated by sharp dissection. The preparation is used for studying high resolution morphology by freeze-substitution and freeze-fracture and for electron probe x-ray microanlysis of sudden calcium displacement from intracellular stores in freeze-dried cryosections, all in the same fiber. We now show the feasibility and instrumentation of new methodology for stimulating a single, intact skeletal muscle fiber at a point resulting in the propagation of an action potential, followed by quick-freezing with sub-millisecond temporal resolution after electrical stimulation, followed by multiple sampling of the frozen muscle fiber for freeze-substitution, freeze-fracture (not shown) and cryosectionmg. This model, at once serving as its own control and obviating consideration of variances between different fibers, frogs etc., is useful to investigate structural and topochemical alterations occurring in the wake of an action potential.

The propagation of action potential in the dendrites of amacrine cells

2000 ◽  
Vol 38 ◽  
pp. S32
Author(s):  
A Koizume
Keyword(s):  
Action Potential ◽  
Amacrine Cells
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