Cortical bone mass, composition, and mechanical properties in female rats in relation to age, long-term ovariectomy, and estrogen substitution

1993 ◽  
Vol 52 (1) ◽  
pp. 26-33 ◽  
Author(s):  
Carl Christian Danielsen ◽  
Lis Mosekilde ◽  
Birgit Svenstrup
Keyword(s):  
Mechanical Properties ◽  
Bone Mass ◽  
Cortical Bone ◽  
Female Rats ◽  
Mass Composition ◽  
Cortical Bone Mass

Effects of long-term sedentary behaviour on the cortical bone mass and distribution during growth: The HAPPY bone study

2017 ◽  
Author(s):  
Rachel L Duckham ◽  
Timo Rantalainen ◽  
Christine Rodda ◽  
Anna Timperio ◽  
Nicola Hawley ◽  
...  
Keyword(s):  
Bone Mass ◽  
Cortical Bone ◽  
Sedentary Behaviour ◽  
Cortical Bone Mass

Effects of long-term immobilisation on cortical bone mass after traumatic amputation of the phalanges estimated by digital X-ray radiogrammetry

2008 ◽  
Vol 19 (9) ◽  
pp. 1291-1299 ◽  
Author(s):  
M.-L. Schäfer ◽  
A. Pfeil ◽  
D. M. Renz ◽  
G. Lehmann ◽  
M. Schmidt ◽  
...  
Keyword(s):  
Bone Mass ◽  
Cortical Bone ◽  
Traumatic Amputation ◽  
X Ray ◽  
Cortical Bone Mass

scholarly journals Retraction: Comparative effects of alendronate and alfacalcidol on cancellous and cortical bone mass and bone mechanical properties in ovariectomized rats

2018 ◽  
Vol 67 (3) ◽  
pp. R2 ◽  
Author(s):  
Jun IWAMOTO ◽  
Azusa SEKI ◽  
Tsuyoshi TAKEDA ◽  
Yoshihiro SATO ◽  
Harumoto YAMADA ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Mass ◽  
Cortical Bone ◽  
Ovariectomized Rats ◽  
Bone Mechanical Properties ◽  
Cortical Bone Mass

Normal Cortical Bone Mass in Patients after Long Term Coumadin Therapy*

1982 ◽  
Vol 54 (2) ◽  
pp. 470-473 ◽  
Author(s):  
LAWRENCE D. PIRO ◽  
MICHAEL P. WHYTE ◽  
WILLIAM A. MURPHY ◽  
STANLEY J. BIRGE
Keyword(s):  
Bone Mass ◽  
Cortical Bone ◽  
Cortical Bone Mass

scholarly journals Elevated Mechanical Loading When Young Provides Lifelong Benefits to Cortical Bone Properties in Female Rats Independent of a Surgically Induced Menopause

Endocrinology ◽  
2013 ◽  
Vol 154 (9) ◽  
pp. 3178-3187 ◽  
Author(s):  
Stuart J. Warden ◽  
Matthew R. Galley ◽  
Andrea L. Hurd ◽  
Joseph M. Wallace ◽  
Maxime A. Gallant ◽  
...  
Keyword(s):  
Bone Mass ◽  
Cortical Bone ◽  
Bone Quality ◽  
Female Rats ◽  
Sprague Dawley ◽  
Bone Properties ◽  
Skeletal Loading ◽  
Cortical Bone Mass ◽  
Independent Effects ◽  
Surgically Induced

Exercise that mechanically loads the skeleton is advocated when young to enhance lifelong bone health. Whether the skeletal benefits of elevated loading when young persist into adulthood and after menopause are important questions. This study investigated the influence of a surgically induced menopause in female Sprague-Dawley rats on the lifelong maintenance of the cortical bone benefits of skeletal loading when young. Animals had their right forearm extrinsically loaded 3 d/wk between 4 and 10 weeks of age using the forearm axial compression loading model. Left forearms were internal controls and not loaded. Animals were subsequently detrained (restricted to cage activities) for 94 weeks (until age 2 years), with ovariectomy (OVX) or sham-OVX surgery being performed at 24 weeks of age. Loading enhanced midshaft ulna cortical bone mass, structure, and estimated strength. These benefits persisted lifelong and contributed to loaded ulnas having greater strength after detraining. Loading also had effects on cortical bone quality. The benefits of loading when young were not influenced by a surgically induced menopause because there were no interactions between loading and surgery. However, OVX had independent effects on cortical bone mass, structure, and estimated strength at early postsurgery time points (up to age 58 weeks) and bone quality measures. These data indicate skeletal loading when young had lifelong benefits on cortical bone properties that persisted independent of a surgically induced menopause. This suggests that skeletal loading associated with exercise when young may provide lifelong antifracture benefits by priming the skeleton to offset the cortical bone changes associated with aging and menopause.

scholarly journals Comparative Therapeutic Effects of Alendronate and Alfacalcidol on Cancellous and Cortical Bone Mass and Mechanical Properties in Ovariectomized Osteopenic Rats

2006 ◽  
Vol 52 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Jun IWAMOTO ◽  
Azusa SEKI ◽  
Tsuyoshi TAKEDA ◽  
Yoshihiro SATO ◽  
Harumoto YAMADA ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Mass ◽  
Cortical Bone ◽  
Therapeutic Effects ◽  
Cortical Bone Mass

Long-term effect of orchidectomy on cortical bone from rat femur: Bone mass and mechanical properties

1992 ◽  
Vol 50 (2) ◽  
pp. 169-174 ◽  
Author(s):  
Carl Christian Danielsen ◽  
Lis Mosekilde ◽  
Troels T. Andreassen
Keyword(s):  
Mechanical Properties ◽  
Bone Mass ◽  
Cortical Bone ◽  
Term Effect ◽  
Rat Femur ◽  
Femur Bone ◽  
Long Term Effect

scholarly journals Comparative Effects of Alendronate and Alfacalcidol on Cancellous and Cortical Bone Mass and Bone Mechanical Properties in Ovariectomized Rats

2006 ◽  
Vol 55 (4) ◽  
pp. 357-367 ◽  
Author(s):  
Jun IWAMOTO ◽  
Azusa SEKI ◽  
Tsuyoshi TAKEDA ◽  
Yoshihiro SATO ◽  
Harumoto YAMADA ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Mass ◽  
Cortical Bone ◽  
Ovariectomized Rats ◽  
Bone Mechanical Properties ◽  
Cortical Bone Mass
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