scholarly journals Comparative Therapeutic Effects of Alendronate and Alfacalcidol on Cancellous and Cortical Bone Mass and Mechanical Properties in Ovariectomized Osteopenic Rats

2006 ◽  
Vol 52 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Jun IWAMOTO ◽  
Azusa SEKI ◽  
Tsuyoshi TAKEDA ◽  
Yoshihiro SATO ◽  
Harumoto YAMADA ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Mass ◽  
Cortical Bone ◽  
Therapeutic Effects ◽  
Cortical Bone Mass

scholarly journals Retraction: Comparative effects of alendronate and alfacalcidol on cancellous and cortical bone mass and bone mechanical properties in ovariectomized rats

2018 ◽  
Vol 67 (3) ◽  
pp. R2 ◽  
Author(s):  
Jun IWAMOTO ◽  
Azusa SEKI ◽  
Tsuyoshi TAKEDA ◽  
Yoshihiro SATO ◽  
Harumoto YAMADA ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Mass ◽  
Cortical Bone ◽  
Ovariectomized Rats ◽  
Bone Mechanical Properties ◽  
Cortical Bone Mass

scholarly journals Comparative Effects of Alendronate and Alfacalcidol on Cancellous and Cortical Bone Mass and Bone Mechanical Properties in Ovariectomized Rats

2006 ◽  
Vol 55 (4) ◽  
pp. 357-367 ◽  
Author(s):  
Jun IWAMOTO ◽  
Azusa SEKI ◽  
Tsuyoshi TAKEDA ◽  
Yoshihiro SATO ◽  
Harumoto YAMADA ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Mass ◽  
Cortical Bone ◽  
Ovariectomized Rats ◽  
Bone Mechanical Properties ◽  
Cortical Bone Mass

Mice lacking estrogen receptor [alpha] in hypothalamic POMC neurons display enhanced estrogenic response on cortical bone mass

2016 ◽  
Author(s):  
Helen Farman ◽  
Sara Windahl ◽  
Deborah Clegg ◽  
Shang Kui Xie ◽  
Lars Westberg ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Bone Mass ◽  
Cortical Bone ◽  
Estrogen Receptor Alpha ◽  
Receptor Alpha ◽  
Cortical Bone Mass

Effects of long-term sedentary behaviour on the cortical bone mass and distribution during growth: The HAPPY bone study

2017 ◽  
Author(s):  
Rachel L Duckham ◽  
Timo Rantalainen ◽  
Christine Rodda ◽  
Anna Timperio ◽  
Nicola Hawley ◽  
...  
Keyword(s):  
Bone Mass ◽  
Cortical Bone ◽  
Sedentary Behaviour ◽  
Cortical Bone Mass

scholarly journals Osteopontin Deficiency Induces Parathyroid Hormone Enhancement of Cortical Bone Formation

Endocrinology ◽  
2003 ◽  
Vol 144 (5) ◽  
pp. 2132-2140 ◽  
Author(s):  
Keiichiro Kitahara ◽  
Muneaki Ishijima ◽  
Susan R. Rittling ◽  
Kunikazu Tsuji ◽  
Hisashi Kurosawa ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Formation ◽  
Bone Mass ◽  
Cortical Bone ◽  
Cancellous Bone ◽  
Wild Type ◽  
Mineral Density ◽  
Cortical Bone Mass ◽  
Intermittent Pth

Intermittent PTH treatment increases cancellous bone mass in osteoporosis patients; however, it reveals diverse effects on cortical bone mass. Underlying molecular mechanisms for anabolic PTH actions are largely unknown. Because PTH regulates expression of osteopontin (OPN) in osteoblasts, OPN could be one of the targets of PTH in bone. Therefore, we examined the role of OPN in the PTH actions in bone. Intermittent PTH treatment neither altered whole long-bone bone mineral density nor changed cortical bone mass in wild-type 129 mice, although it enhanced cancellous bone volume as reported previously. In contrast, OPN deficiency induced PTH enhancement of whole-bone bone mineral density as well as cortical bone mass. Strikingly, although PTH suppressed periosteal bone formation rate (BFR) and mineral apposition rate (MAR) in cortical bone in wild type, OPN deficiency induced PTH activation of periosteal BFR and MAR. In cancellous bone, OPN deficiency further enhanced PTH increase in BFR and MAR. Analysis on the cellular bases for these phenomena indicated that OPN deficiency augmented PTH enhancement in the increase in mineralized nodule formation in vitro. OPN deficiency did not alter the levels of PTH enhancement of the excretion of deoxypyridinoline in urine, the osteoclast number in vivo, and tartrate-resistant acid phosphatase-positive cell development in vitro. These observations indicated that OPN deficiency specifically induces PTH activation of periosteal bone formation in the cortical bone envelope.

scholarly journals A New Synthetic Steroid, Osaterone Acetate (TZP-4238), Increases Cortical Bone Mass and Strength by Enhancing Bone Formation in Ovariectomized Rats

1997 ◽  
Vol 12 (4) ◽  
pp. 590-597 ◽  
Author(s):  
Hiroaki Fuse ◽  
Seiji Fukumoto ◽  
Hideyuki Sone ◽  
Yoshiko Miyata ◽  
Tomoyuki Saito ◽  
...  
Keyword(s):  
Bone Formation ◽  
Bone Mass ◽  
Cortical Bone ◽  
Ovariectomized Rats ◽  
Cortical Bone Mass
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