High voltage electron microscopic studies of endothelial cell tubular structures in the mouse blood-brain barrier following brain trauma

1989 ◽  
Vol 77 (5) ◽  
pp. 480-488 ◽  
Author(s):  
A. S. Lossinsky ◽  
M. J. Song ◽  
H. M. Wisniewski
Keyword(s):  
Endothelial Cell ◽  
Blood Brain Barrier ◽  
High Voltage ◽  
Brain Trauma ◽  
Brain Barrier ◽  
Tubular Structures ◽  
Electron Microscopic ◽  
Mouse Blood ◽  
Voltage Electron ◽  
Microscopic Studies

Characterization of Endothelial Cell Transport in the Developing Mouse Blood-Brain Barrier

1986 ◽  
Vol 8 (2) ◽  
pp. 61-75 ◽  
Author(s):  
Albert S. Lossinsky ◽  
Andrzej W. Vorbrodt ◽  
Henryk M. Wisniewski
Keyword(s):  
Endothelial Cell ◽  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Mouse Blood ◽  
Cell Transport ◽  
Blood Brain

Experimental Disruption of the Blood-Brain Barrier System in an Insect (Periplaneta Americana)

1973 ◽  
Vol 59 (3) ◽  
pp. 711-724
Author(s):  
J. E. TREHERNE
Keyword(s):  
Blood Brain Barrier ◽  
Periplaneta Americana ◽  
Brain Barrier ◽  
Ultrastructural Changes ◽  
Hypertonic Solution ◽  
Electron Microscopic ◽  
Blood Brain ◽  
Ionic Lanthanum ◽  
Electrophysiological Studies ◽  
Microscopic Studies

1. The effects of hypertonic urea and hypertonic glucose solutions upon the ‘blood-brain barrier’ in the isolated abdominal nerve cord of the cockroach have been studied. 2. Electrophysiological studies showed that a hypertonic solution of urea, but not of glucose, was effective in reducing the barrier to the entry of potassium and the loss of sodium. 3. Electron-microscopic studies revealed no significant ultrastructural changes, and no disruption of the perineurial barrier to the entry of ionic lanthanum, following comparable exposure to the hypertonic solutions. 4. It is suggested that this alteration of the blood-brain barrier may result from a selective change in permeability of the perineurial membranes or tight junctions.

Scanning electron microscopic study of collagen fibrillogenesis and extracellular compartmentalization in the chick embryo tendon

1986 ◽  
Vol 44 ◽  
pp. 208-209
Author(s):  
Grace C.H. Yang
Keyword(s):  
Chick Embryo ◽  
Extracellular Space ◽  
Fibroblast Cell ◽  
Collagen Fibrils ◽  
Electron Microscopic ◽  
Voltage Electron ◽  
Scanning Electron Microscopic Study ◽  
Microscopic Studies ◽  
And Function

The size and organization of collagen fibrils in the extracellular matrix is an important determinant of tissue structure and function. The synthesis and deposition of collagen involves multiple steps which begin within the cell and continue in the extracellular space. High-voltage electron microscopic studies of the chick embryo cornea and tendon suggested that the extracellular space is compartmentalized by the fibroblasts for the regulation of collagen fibril, bundle, and tissue specific macroaggregate formation. The purpose of this study is to gather direct evidence regarding the association of the fibroblast cell surface with newly formed collagen fibrils, and to define the role of the fibroblast in the control and the precise positioning of collagen fibrils, bundles, and macroaggregates during chick tendon development.

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