Fibrous astrocytes in Alzheimer's disease and senile dementia of Alzheimer's type

1983 ◽  
Vol 61 (1) ◽  
pp. 76-80 ◽  
Author(s):  
G. L. Mancardi ◽  
B. H. Liwnicz ◽  
T. I. Mandybur
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Senile Dementia ◽  
Dementia Of Alzheimer’S Type ◽  
Fibrous Astrocytes

Lipid Composition in Different Regions of the Brain in Alzheimer's Disease/Senile Dementia of Alzheimer's Type

1992 ◽  
Vol 59 (5) ◽  
pp. 1646-1653 ◽  
Author(s):  
M. SoOderberg ◽  
C. Edlund ◽  
I. Alafuzoff ◽  
K. Kristensson ◽  
G. Dallner
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Lipid Composition ◽  
Senile Dementia ◽  
Dementia Of Alzheimer’S Type ◽  
The Brain

scholarly journals Alzheimer’s disease as the cerebral cortex disorder

2019 ◽  
Vol 4 (2) ◽  
pp. 16-20
Author(s):  
Volobuev AN ◽  
Romanchuk PI ◽  
Bulgakova SV
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Information Transfer ◽  
Brain Cortex ◽  
Senile Dementia ◽  
Memory Storage ◽  
Neuronal Circuits ◽  
Storage Element ◽  
Dementia Of Alzheimer’S Type ◽  
The Brain

Objectives – to highlight the structure, function and localization of Alzheimer’s disease and to specify cognitive impairments related to it. Material and methods. The anatomic data of human brain structure were used. Results. The patterns of memory formation in the brain cortex are investigated. The brain cortex is presented as a type of syncytium consisting of elementary neural structures – cyclic neuronal circuits – memory elements. All cyclic neuronal circuits in a brain cortex are functionally interconnected. The connections between the neuronal circuits can be determined (imprinted) and stochastic (random). The intensity of stochastic communications defines the person's potential for creativity. The impairment of cyclic neuronal circuit connections results in either Alzheimer’s disease or in senile dementia of Alzheimer’s type. Conclusion. In case the cortex is considered as the syncytium, the memory storage element, it can be the reason of the human creativity. It is shown that the failure of the information transfer in the cortex syncytium or neurons destruction in the neuronal network results in Alzheimer’s disease or in senile dementia of Alzheimer’s type.

Apolipoprotein E ε 4 is a risk factor for Alzheimer's disease and senile dementia of Alzheimer's type

1997 ◽  
Vol 42 (1) ◽  
pp. 91S
Author(s):  
G. Korovaitseva ◽  
S. Keryanov ◽  
S. Petruk ◽  
Y. Molyaka ◽  
N. Selezneva ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Risk Factor ◽  
Apolipoprotein E ◽  
Senile Dementia ◽  
Dementia Of Alzheimer’S Type

scholarly journals Caretaker Obstreperous Behavior Rating Scale

1997 ◽  
Vol 8 (S3) ◽  
pp. 321-324 ◽  
Author(s):  
Joan M. Swearer ◽  
David A. Drachman
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Rating Scale ◽  
Late Onset ◽  
Senile Dementia ◽  
Medical Personnel ◽  
Original Description ◽  
Behavior Rating Scale ◽  
Large Patient ◽  
Number Of Patients

Although Alzheimer's original description of the dementing disorder that bears his name emphasized the prominence of troublesome and disruptive behaviors, a systematic investigation of behavioral disturbances of dementia did not begin in earnest until the 1980s. At that time, as the neuropathologic identity of presenile Alzheimer's disease and late-onset “senile dementia” was recognized, the redefinition of Alzheimer's disease abruptly increased the number of patients diagnosed with this condition. Physicians and other medical personnel working with Alzheimer's disease patients recognized both the importance of abnormal behaviors in this now large patient population and the need to describe, classify, and quantify these behaviors.

A Study on the Symptomatology and Differential Diagnosis of Alzheimer's Disease and Pick's Disease

1943 ◽  
Vol 89 (374) ◽  
pp. 1-20 ◽  
Author(s):  
E. Stengel
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Differential Diagnosis ◽  
Mental Hospital ◽  
Senile Dementia ◽  
Clinical Entity ◽  
Mental Condition ◽  
Pick's Disease ◽  
Pick’S Disease ◽  
Vascular Origin

Many problems concerning Alzheimer's disease and Pick's disease are still awaiting clarification. In this country Henderson was the first to draw attention to the considerable importance of Alzheimer's disease in clinical psychiatry. Valuable work has been contributed by various writers in recent years (Grunthal, 1936; Critchley, 1929, 1930, 1931, 1938; Schottky, 1932; Thorpe, 1932; Rothschild, 1934; Malamud, Lowenberg and co-workers, 1929; Mayer-Gross, 1938; Kasanin and Crank, 1933; Jervis and Soltz, 1936; McMenemy, a.o., 1939). While Pick's disease has retained its position as a clinical entity based mainly on the characteristic anatomical picture, the position of Alzheimer's disease in the system of psychiatry has become more complicated; for instance atypical cases have been described presenting the anatomical characters of Alzheimer's disease, though not fitting into the original clinical conception of that disease. Lowenberg and his co-workers (1929) are inclined to regard Alzheimer's disease as a syndrome rather than a clinical entity. Many contributors have directed their main interest to the pathological changes. The knowledge of the symptomatology of those conditions is still incomplete. Further intensive study may enable us not only to base the diagnosis and differential diagnosis of Alzheimer's disease and Pick's disease on more solid clinical knowledge than hitherto, but also to recognize the early stages of those diseases before advancing cerebral degeneration effaces their characteristic clinical features. Unfortunately, most of the cases come under the observation of the psychiatrist only in the later stages of their illness, and it seems that the comparatively small proportion of the mental hospital population they represent does not reflect the incidence of those diseases. It is very likely that many patients die from intercurrent illnesses before their mental condition is recognized or sufficiently advanced to make admission to a mental hospital necessary. The differential diagnosis of those conditions offers considerable difficulties which often may prove insuperable. Alzheimer's disease and Pick's disease have to be distinguished not only from each other but from conditions of vascular origin, from senile dementia and various atypical conditions which occur at the same age period during which Alzheimer's disease and Pick's disease usually develop. Only careful collection and analysis of clinical observations and their scrutiny by pathological investigations can increase our still limited knowledge in this important field of psychiatry.

scholarly journals Emotional Working Memory and Alzheimer’s Disease

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Nicola Mammarella ◽  
Beth Fairfield
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Working Memory ◽  
Memory Performance ◽  
Memory Task ◽  
Emotional Information ◽  
Healthy Older Adults ◽  
Affective Stimuli ◽  
Age Related ◽  
Dementia Of Alzheimer’S Type

A number of recent studies have reported that working memory does not seem to show typical age-related deficits in healthy older adults when emotional information is involved. Differently, studies about the short-term ability to encode and actively manipulate emotional information in dementia of Alzheimer’s type are few and have yielded mixed results. Here, we review behavioural and neuroimaging evidence that points to a complex interaction between emotion modulation and working memory in Alzheimer’s. In fact, depending on the function involved, patients may or may not show an emotional benefit in their working memory performance. In addition, this benefit is not always clearly biased (e.g., towards negative or positive information). We interpret this complex pattern of results as a consequence of the interaction between multiple factors including the severity of Alzheimer’s disease, the nature of affective stimuli, and type of working memory task.

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