Effect of disturbance of motor function on properties of the skeletal muscle fiber membrane

1983 ◽  
Vol 96 (5) ◽  
pp. 1520-1523
Author(s):  
E. M. Volkov ◽  
G. A. Nasledov ◽  
G. I. Poletaev
Keyword(s):  
Skeletal Muscle ◽  
Motor Function ◽  
Muscle Fiber ◽  
Skeletal Muscle Fiber ◽  
Fiber Membrane ◽  
Muscle Fiber Membrane

Role of opioid peptides in neurotrophic control of sensitivity of the rat skeletal muscle fiber membrane to acetylcholine

1987 ◽  
Vol 104 (5) ◽  
pp. 1491-1493
Author(s):  
A. V. Chikin ◽  
A. Kh. Urazaev ◽  
E. M. Volkov ◽  
G. I. Poletaev ◽  
Kh. S. Khamitov
Keyword(s):  
Skeletal Muscle ◽  
Muscle Fiber ◽  
Opioid Peptides ◽  
Skeletal Muscle Fiber ◽  
Neurotrophic Control ◽  
Fiber Membrane ◽  
Rat Skeletal Muscle ◽  
Muscle Fiber Membrane

scholarly journals Direct visualization of the dystrophin network on skeletal muscle fiber membrane.

1992 ◽  
Vol 119 (5) ◽  
pp. 1183-1191 ◽  
Author(s):  
V Straub ◽  
R E Bittner ◽  
J J Léger ◽  
T Voit
Keyword(s):  
Skeletal Muscle ◽  
Plasma Membrane ◽  
Muscle Fiber ◽  
Fiber Surface ◽  
Protein Product ◽  
Skeletal Muscle Fiber ◽  
Cytoskeletal Proteins ◽  
Dmd Gene ◽  
Muscle Fiber Membrane ◽  
Internal Domain

Dystrophin, the protein product of the Duchenne muscular dystrophy (DMD) gene locus, is expressed on the muscle fiber surface. One key to further understanding of the cellular function of dystrophin would be extended knowledge about its subcellular organization. We have shown that dystrophin molecules are not uniformly distributed over the humen, rat, and mouse skeletal muscle fiber surface using three independent methods. Incubation of single-teased muscle fibers with antibodies to dystrophin revealed a network of denser transversal rings (costameres) and finer longitudinal interconnections. Double staining of longitudinal semithin cryosections for dystrophin and alpha-actinin showed spatial juxtaposition of the costameres to the Z bands. Where peripheral myonuclei precluded direct contact of dystrophin to the Z bands the organization of dystrophin was altered into lacunae harboring the myonucleus. These lacunae were surrounded by a dystrophin ring and covered by a more uniform dystrophin veil. Mechanical skinning of single-teased fibers revealed tighter mechanical connection of dystrophin to the plasma membrane than to the underlying internal domain of the muscle fiber. The entire dystrophin network remained preserved in its structure on isolated muscle sarcolemma and identical in appearance to the pattern observed on teased fibers. Therefore, connection of defined areas of plasma membrane or its constituents such as ion channels to single sarcomeres might be a potential function exerted by dystrophin alone or in conjunction with other submembrane cytoskeletal proteins.

How to sample the entire length of a single muscle fiber quick-frozen after electrical point stimulation for high resolution EM

1992 ◽  
Vol 50 (1) ◽  
pp. 776-777
Author(s):  
Joachim R. Sommer ◽  
Teresa High ◽  
Betty Scherer ◽  
Isaiah Taylor ◽  
Rashid Nassar
Keyword(s):  
Skeletal Muscle ◽  
High Resolution ◽  
Action Potential ◽  
Muscle Fiber ◽  
Freeze Fracture ◽  
Freeze Substitution ◽  
Electrical Field Stimulation ◽  
Skeletal Muscle Fiber ◽  
Freeze Dried ◽  
Quick Freezing

We have developed a model that allows the quick-freezing at known time intervals following electrical field stimulation of a single, intact frog skeletal muscle fiber isolated by sharp dissection. The preparation is used for studying high resolution morphology by freeze-substitution and freeze-fracture and for electron probe x-ray microanlysis of sudden calcium displacement from intracellular stores in freeze-dried cryosections, all in the same fiber. We now show the feasibility and instrumentation of new methodology for stimulating a single, intact skeletal muscle fiber at a point resulting in the propagation of an action potential, followed by quick-freezing with sub-millisecond temporal resolution after electrical stimulation, followed by multiple sampling of the frozen muscle fiber for freeze-substitution, freeze-fracture (not shown) and cryosectionmg. This model, at once serving as its own control and obviating consideration of variances between different fibers, frogs etc., is useful to investigate structural and topochemical alterations occurring in the wake of an action potential.

Parsing the microRNA genetics basis regulating skeletal muscle fiber types and meat quality traits in pigs

2021 ◽  
Author(s):  
A. Jiang ◽  
D. Yin ◽  
L. Zhang ◽  
B. Li ◽  
R. Li ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Meat Quality ◽  
Muscle Fiber ◽  
Skeletal Muscle Fiber ◽  
Muscle Fiber Types ◽  
Fiber Types ◽  
Quality Traits ◽  
Meat Quality Traits

scholarly journals Pre-training Skeletal Muscle Fiber Size and Predominant Fiber Type Best Predict Hypertrophic Responses to 6 Weeks of Resistance Training in Previously Trained Young Men

2019 ◽  
Vol 10 ◽  
Author(s):  
Cody T. Haun ◽  
Christopher G. Vann ◽  
C. Brooks Mobley ◽  
Shelby C. Osburn ◽  
Petey W. Mumford ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Resistance Training ◽  
Muscle Fiber ◽  
Fiber Type ◽  
Young Men ◽  
Skeletal Muscle Fiber ◽  
Fiber Size

Extensive motor neuron survival in the absence of secondary skeletal muscle fiber formation

1996 ◽  
Vol 45 (1) ◽  
pp. 57-68 ◽  
Author(s):  
T.J. Brennan ◽  
E.N. Olson ◽  
W.H. Klein ◽  
J.W. Winslow
Keyword(s):  
Skeletal Muscle ◽  
Motor Neuron ◽  
Muscle Fiber ◽  
Skeletal Muscle Fiber ◽  
Fiber Formation ◽  
Neuron Survival ◽  
Motor Neuron Survival

Confocal microscopy study of membrane organelles of the skeletal muscle fiber in the process of Zenker’s (spreading) necrosis

2007 ◽  
Vol 1 (2) ◽  
pp. 183-190 ◽  
Author(s):  
S. A. Krolenko ◽  
S. Ya. Adamyan ◽  
T. N. Belyaeva ◽  
T. P. Mozhenok ◽  
A. V. Salova
Keyword(s):  
Skeletal Muscle ◽  
Confocal Microscopy ◽  
Muscle Fiber ◽  
Microscopy Study ◽  
Skeletal Muscle Fiber
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