The effect of erythropoietin on the cellular defence mechanism of red blood cells in children with chronic renal failure

1992 ◽  
Vol 6 (6) ◽  
pp. 536-541 ◽  
Author(s):  
S�ndor T�ri ◽  
Ilona N�meth ◽  
Ilona Varga ◽  
Tibor Bodrogi ◽  
B�la Matkovics
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Defence Mechanism ◽  
Cellular Defence

Metabolism of Red Blood Cells in Chronic Renal Failure

Nephron ◽  
1979 ◽  
Vol 24 (1) ◽  
pp. 21-24 ◽  
Author(s):  
J.L. Rodríguez-Commes ◽  
J.M. Tabernero ◽  
P. Martin-Vasallo ◽  
S. DeCastro ◽  
E. Battaner
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Red Blood Cells ◽  
Blood Cells

scholarly journals HAEMATOLOGICAL PARAMETERS AMONG SUDANESE PATIENTS WITH CHRONIC RENAL FAILURE

2016 ◽  
Vol 4 (1) ◽  
pp. 50-54
Author(s):  
RaianBakhet Yassein ◽  
Nada Omer Alseedig ◽  
SihamKhalifaAbd Allah ◽  
AreegAlsail Mohmmed ◽  
NosibaAbdelmajid Alballah ◽  
...  
Keyword(s):  
Renal Failure ◽  
Platelet Count ◽  
Chronic Renal Failure ◽  
Red Blood Cells ◽  
Blood Cells ◽  
White Blood Cells ◽  
Haemoglobin Concentration ◽  
Haematological Parameters ◽  
Common Causes ◽  
Hb Concentration

Chronic renal failure is one of the more common causes of morbidity and mortality among Sudanese. This study describes altered haemoglobin concentration (Hb), haematochrit percent (Hct), red blood cells count (RBCs), platelet count (Plts) and white blood cells count (WBCs) in patients with chronic renal failure and describes the effect of disease duration on haemoglobin concentration and red blood cells count. Methods: Haematological parameters in (50) patients with Chronic renal failure and (50) age and sex matched controls were evaluated, living in Shendi locality in northern Sudan. The results of this study showed that mean of Hb concentration, RBCs count, Hct percent and platelet count were exhibited significant decreased, but mean of WBCs count was insignificantly increased. Increased duration of the disease lead to significantly decreased on mean of Hb concentration and RBCs count. Chronic renal failure is associated with different degrees of reduced haematological parameters. Also increase duration of the disease lead to significantly decrease in mean of Hb concentration and RBCs count.

scholarly journals Evidence of an Increased Susceptibility to Lipid Peroxidation in Red Blood Cells of Chronic Renal Failure Patients

Nephron ◽  
1988 ◽  
Vol 50 (1) ◽  
pp. 64-65 ◽  
Author(s):  
Amparo Miguel ◽  
Alicia Miguel ◽  
Mariano Linares ◽  
Alfonso Perez ◽  
Rosa Moll ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Increased Susceptibility

scholarly journals Potassium concentration of red blood cells in patients with acute or chronic renal failure.

1990 ◽  
Vol 23 (12) ◽  
pp. 1349-1355
Author(s):  
Shigehiro Miki ◽  
Shigekazu Yuasa ◽  
Takafumi Yura ◽  
Tooru Sumikura ◽  
Norihiro Takahashi ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Potassium Concentration

Physical Properties of the Red Blood Cells in Chronic Renal Failure

Nephron ◽  
1991 ◽  
Vol 59 (2) ◽  
pp. 271-278 ◽  
Author(s):  
M. Viljoen ◽  
A.A. de Oliveira ◽  
F.J. Milne
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Physical Properties ◽  
Red Blood Cells ◽  
Blood Cells

Estimation of pore passage time of red blood cells in normal subjects and patients with renal failure

1980 ◽  
Vol 36 (3) ◽  
pp. 325-327 ◽  
Author(s):  
Y. Kikuchi ◽  
M. Horimoto ◽  
T. Koyama ◽  
Y. Koyama ◽  
S. Tozawa
Keyword(s):  
Renal Failure ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Normal Subjects ◽  
Passage Time

Polyagglutinability of Red Blood Cells Complicating Treatment with the Artificial Kidney in two Cases of Acute Renal Failure

2009 ◽  
Vol 167 (2) ◽  
pp. 149-152 ◽  
Author(s):  
Per Erlanson ◽  
Tore Lindholm ◽  
Bengt Lindqvist ◽  
Bengt Löw
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Artificial Kidney

scholarly journals Changes in red blood cell membrane structure in patients with chronic renal failure.

1997 ◽  
Vol 44 (1) ◽  
pp. 99-107 ◽  
Author(s):  
K Gwoździński ◽  
M Janicka ◽  
J Brzeszczyńska ◽  
M Luciak
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Membrane Protein ◽  
Blood Cell ◽  
Hydroxyl Radicals ◽  
Red Blood Cell ◽  
Blood Cells ◽  
Membrane Structure ◽  
Osmotic Fragility ◽  
Tert Butylhydroperoxide

The properties of red blood cell membranes in patients with chronic renal failure were investigated using electron paramagnetic resonance spectroscopy. Using spin traps, 5,5-dimethylpirroline-1 oxide and N-tert-butyl-alpha-phenylnitrone, we found generation of hydroxyl radicals in the blood of patients with chronic renal failure after 20 min of regular hemodialysis. The physical state of membrane proteins and membrane osmotic fragility and reductive properties of red blood cells were studied. The increase in the relative correlation time of 4-(2-iodoacetamido)-2,2,6,6-tetramethylpiperidine-1 oxyl indicates the immobilization of membrane protein molecules in erythrocytes of chronic renal failure patients. The decrease in membrane protein mobility was observed in whole blood incubated with tert-butylhydroperoxide, regardless of the presence of iron. We found that the addition of ferrous ions did not aggravate profound changes in membrane proteins induced with tert-butylhydroperoxide. We also demonstrated higher osmotic fragility of erythrocytes in the patients with renal failure as compared to normal subjects. These alterations in membrane structure of red blood cells in hemodialysed patients suggest that hydroxyl radicals generated during hemodialysis can play an important role in the oxidative mechanism of erythrocyte damage.

Acute Renal Failure following Transfusion of Accidentally Frozen Autologous Red Blood Cells

Vox Sanguinis ◽  
1989 ◽  
Vol 56 (4) ◽  
pp. 293-293 ◽  
Author(s):  
J.J. Lanore ◽  
M.C. Quarré ◽  
G. Audibert ◽  
J.D. Chiche ◽  
G. Woimant ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Red Blood Cells ◽  
Blood Cells

Characteristics of Peripheral and Peritoneal White Blood Cells in Children with Chronic Renal Failure, Dialyzed or Not

2000 ◽  
Vol 20 (6) ◽  
pp. 748-756 ◽  
Author(s):  
Antonia H.M. Bouts ◽  
Theo A. Out ◽  
Cornelis H. Schröder ◽  
Leo A.H. Monnens ◽  
Jeroen Nauta ◽  
...  
Keyword(s):  
Renal Failure ◽  
T Cells ◽  
Peritoneal Dialysis ◽  
Chronic Renal Failure ◽  
Natural Killer Cells ◽  
Natural Killer ◽  
Blood Cells ◽  
White Blood Cells ◽  
Healthy Children ◽  
Killer Cells

Objective To explore further the mechanisms leading to immune deficiency in chronic renal failure and the role of dialysis treatment in these mechanisms. Design Cross-sectional and longitudinal analysis. Patients We studied 39 children treated with peritoneal dialysis (PD), 23 children treated with hemodialysis (HD), 33 children not yet dialyzed [chronic renal failure (CRF)], and 27 healthy children. Peritoneal cells were also obtained from PD children for analysis. Methods White blood cells (WBCs) were isolated from blood and peritoneal dialysis effluent by centrifugation. The number of CD2+, CD4+, and CD8+ T cells, B cells, and natural killer cells were measured by flow cytometry. Results The total peripheral blood lymphocyte count was lower in PD children (2.6 x 109/L), HD children (2.1 x 109/L), and CRF children (2.0 x 109/L) compared with healthy children (3.1 x 109/L, p < 0.05). The B lymphocyte count was also lower in PD children (0.34x109/L), HD children (0.22 x 109/L), and CRF children (0.33 x 109/L) compared with healthy children (0.52 x 109/L, p < 0.01). Numbers of CD4+ T cells were not different, but numbers of CD8+ T cells were lower in PD children (0.56 x 109/L), HD children (0.63 x 109/L), and CRF children (0.53 x 109/L) compared with healthy children (0.77 x 109/L, p < 0.05). The count of natural killer cells was lower in PD children (0.21 x 109/L), HD children (0.17 x 109/L), and CRF children (0.18 x 109/L) compared with healthy children (0.50 x 109/L, p < 0.0001). The CD4/CD8 ratio of lymphocytes in peritoneal effluent was 0.8 versus 1.9 in peripheral blood ( p < 0.001). The CD2/CD19 ratio was not different. The cell subsets remained stable during the first year of PD treatment. The CD2/CD19 ratio in peritoneal effluent was higher in children with a peritonitis incidence ≥ 1 per year. Conclusions The reduced numbers of B lymphocytes, CD8+ T cells, and natural killer cells found in CRF children, dialyzed or not, may favor the frequent occurrence of infections.

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