Natural and synthetic analogues of melatonin and related compounds II. Effects on plasma thyroid hormones and cholesterol levels in male Syrian hamsters

1983 ◽  
Vol 56 (4) ◽  
pp. 279-291 ◽  
Author(s):  
Mary K. Vaughan ◽  
B. A. Richardson ◽  
Linda Y. Johnson ◽  
L. J. Petterborg ◽  
M. C. Powanda ◽  
...  
Keyword(s):  
Thyroid Hormones ◽  
Synthetic Analogues ◽  
Syrian Hamsters ◽  
Cholesterol Levels ◽  
Related Compounds ◽  
Natural And Synthetic

Interaction of Ageing, Photoperiod and Melatonin on Plasma Thyroid Hormones and Cholesterol Levels in Female Syrian Hamsters (Mesocricetus auratus)

Gerontology ◽  
1982 ◽  
Vol 28 (6) ◽  
pp. 345-353 ◽  
Author(s):  
M.K. Vaughan ◽  
B.A. Richardson ◽  
C.M. Craft ◽  
M.C. Powanda ◽  
R.J. Reiter
Keyword(s):  
Thyroid Hormones ◽  
Mesocricetus Auratus ◽  
Syrian Hamsters ◽  
Cholesterol Levels

Natural and synthetic analogues of melatonin and related compounds I. Effects on the reproductive system of the male Syrian hamster

1983 ◽  
Vol 56 (2-3) ◽  
pp. 187-197 ◽  
Author(s):  
B. A. Richardson ◽  
Mary K. Vaughan ◽  
L. J. Petterborg ◽  
Linda Y. Johnson ◽  
T. S. King ◽  
...  
Keyword(s):  
Reproductive System ◽  
Syrian Hamster ◽  
Synthetic Analogues ◽  
Related Compounds ◽  
Natural And Synthetic

Semi-synthesis as a tool for broadening the health applications of bioactive olive secoiridoids: a critical review

2021 ◽  
Author(s):  
Manuela Oliverio ◽  
Monica Nardi ◽  
Maria Luisa Di Gioia ◽  
Paola Costanzo ◽  
Sonia Bonacci ◽  
...  
Keyword(s):  
Critical Review ◽  
Natural Compounds ◽  
Effective Strategy ◽  
Synthetic Analogues ◽  
Health Applications ◽  
Natural And Synthetic

Semi-synthesis is an effective strategy to obtain both natural and synthetic analogues of the olive secoiridoids, starting from easy accessible natural compounds.

Effects of Injections and/or Chronic Implants of Melatonin and 5-Methoxytryptamine on Plasma Thyroid Hormones in Male and Female Syrian Hamsters

1984 ◽  
Vol 39 (4) ◽  
pp. 361-366 ◽  
Author(s):  
Mary K. Vaughan ◽  
Bruce A. Richardson ◽  
Larry J. Petterborg ◽  
Anke P. Holtorf ◽  
George M. Vaughan ◽  
...  
Keyword(s):  
Thyroid Hormones ◽  
Male And Female ◽  
Syrian Hamsters

Soy Protein with or Without Isoflavones, Soy Germ and Soy Germ Extract, and Daidzein Lessen Plasma Cholesterol Levels in Golden Syrian Hamsters

2003 ◽  
Vol 228 (9) ◽  
pp. 1063-1068 ◽  
Author(s):  
Tongtong Song ◽  
Sun-Ok Lee ◽  
Patricia A. Murphy ◽  
Suzanne Hendrich
Keyword(s):  
Soy Protein ◽  
Plasma Cholesterol ◽  
Syrian Hamsters ◽  
Cholesterol Levels

PLATELET FUNCTION AND LIPOPROTEINS IN PATIENTS WITH HYPOTHYROIDISM

1987 ◽  
Author(s):  
S Fujii ◽  
T Kariya
Keyword(s):  
Platelet Aggregation ◽  
Thyroid Hormones ◽  
Platelet Function ◽  
Gel Electrophoresis ◽  
Atp Release ◽  
Serum Lipoprotein ◽  
Platelet Factor ◽  
Cholesterol Levels ◽  
Gradient Gel Electrophoresis ◽  
Hdl Metabolism

Platelet function and serum lipoprotein levels were studied in ten patients (two males and eight females) with hypothyroidism. Platelet aggregation and ATP release were determined by Lumi-aggregometer using ADP , collagen and epinephrine as stimulants. Platelet factor 4 (PF4) and thromboxane B2 (TXB2) were determined by radioimmunoassay. High density lipoproteincholesterol (HDL-C) was determined by heparin-manga-nese method. HDL subfractions were separated by gradient gel electrophoresis (PAA 4/30). Apolipopro-teins were measured by single radial immunodiffusion. Platelet aggregation increased in those patients at stimulating by epinephrine. ATP release also increased at stimulating by epinephrine. PF4 increased at stimulating by epinephrine. TXB2 increased at stimu-lating--by ADP or epinephrine significantly (p<0.05), respectively. Platelet aggregation was not correlated with thyroid hormones or total cholesterol levels.But it had a positive correlation tendency with HDL-C or HDL2-C and a negative one with HDL3-C levels.These results suggested some relationships between platelet function and HDL metabolism in patients with hypothyroidism.

scholarly journals Hypercholesterolemia in Two Siblings with Resistance to Thyroid Hormones Due to Disease-Causing Variant in Thyroid Hormone Receptor (THRB) Gene

Medicina ◽  
2020 ◽  
Vol 56 (12) ◽  
pp. 699
Author(s):  
Maja Pajek ◽  
Magdalena Avbelj Stefanija ◽  
Katarina Trebusak Podkrajsek ◽  
Jasna Suput Omladic ◽  
Mojca Zerjav Tansek ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Thyroid Hormones ◽  
Hormone Receptor ◽  
Thyroid Hormone Receptor ◽  
Pathogenic Mutation ◽  
Laboratory Findings ◽  
Cholesterol Levels ◽  
Resistance To Thyroid Hormones ◽  
Hormonal Resistance ◽  
Disease Variant

Resistance to thyroid hormone beta (RTHβ) is a syndrome characterized by a reduced response of target tissues to thyroid hormones. In 85% of cases, a pathogenic mutation in the thyroid hormone receptor beta (THRB) gene is found. The clinical picture of RTHβ is very diverse; the most common findings are goiter and tachycardia, but the patients might be clinically euthyroid. The laboratory findings are almost pathognomonic with elevated free thyroxin (fT4) levels and high or normal thyrotropin (TSH) levels; free triiodothyronin (fT3) levels may also be elevated. We present three siblings with THRB mutation (heterozygous disease-variant c.727C>T, p.Arg243Trp); two of them also had hypercholesterolemia, while all three had several other clinical characteristics of RTHβ. This is the first description of the known Slovenian cases with RTHβ due to the pathogenic mutation in the THRB gene. Hypercholesterolemia might be etiologically related with RTHβ, since the severity of hormonal resistance varies among different tissues and hypercholesterolemia in patients with THRB variants might indicate the relatively hypothyroid state of the liver. We suggest that cholesterol levels are measured in all RTHβ patients.

Injections and/or implants of 6-chloromelatonin and melatonin: effects on plasma thyroid hormones in male and female syrian hamsters

1984 ◽  
Vol 20 (6) ◽  
pp. 1471
Author(s):  
M.K. Vaughan ◽  
B.A. Richardson ◽  
L.J. Petterborg ◽  
G.M. Vaughan ◽  
R.J. Reiter
Keyword(s):  
Thyroid Hormones ◽  
Male And Female ◽  
Syrian Hamsters
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