Prognostic value of the combined assessment of proliferating cell nuclear antigen immunostaining and nuclear DNA content in invasive human mammary carcinomas

1993 ◽  
Vol 423 (4) ◽  
pp. 273-279 ◽  
Author(s):  
Hendrik Schimmelpenning ◽  
Elina T. Eriksson ◽  
Bo Franzén ◽  
Anders Zetterberg ◽  
Gert U. Auer
Keyword(s):  
Dna Content ◽  
Proliferating Cell Nuclear Antigen ◽  
Prognostic Value ◽  
Nuclear Dna ◽  
Nuclear Dna Content ◽  
Nuclear Antigen ◽  
Mammary Carcinomas ◽  
Proliferating Cell

Nuclear DNA content, proliferating-cell nuclear antigen (PCNA) and p53 immunostaining in predicting progression of laryngeal cancer in situ lesions

2007 ◽  
Vol 56 (1) ◽  
pp. 95-99 ◽  
Author(s):  
Eva Munck-Wikland ◽  
Staffan Edström ◽  
Eva Jungmark ◽  
Richard Kuylenstierna ◽  
Johan Lindholm ◽  
...  
Keyword(s):  
Laryngeal Cancer ◽  
Dna Content ◽  
Proliferating Cell Nuclear Antigen ◽  
Nuclear Dna ◽  
Nuclear Dna Content ◽  
Nuclear Antigen ◽  
Proliferating Cell

Prognostic value of nuclear DNA content in papillary and follicular thyroid cancer

1988 ◽  
Vol 12 (4) ◽  
pp. 503-507 ◽  
Author(s):  
Jaap F. Hamming ◽  
Lodewijk J. D. M. Schelfhout ◽  
Cees J. Cornelisse ◽  
Cornelis J. H. van de Velde ◽  
Bernard M. Goslings ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Dna Content ◽  
Prognostic Value ◽  
Nuclear Dna ◽  
Nuclear Dna Content ◽  
Follicular Thyroid Cancer

Nuclear DNA Content in Mammary Carcinomas in Women Aged 35 or Younger

1986 ◽  
Vol 9 (5) ◽  
pp. 382-386 ◽  
Author(s):  
Anette von Rosen ◽  
Anders Fallenius ◽  
Birgitta Sundelin ◽  
Gert Auer
Keyword(s):  
Dna Content ◽  
Nuclear Dna ◽  
Nuclear Dna Content ◽  
Mammary Carcinomas

scholarly journals Phosphorylation of p53 Serine 15 Is a Predictor of Survival for Patients with Hepatocellular Carcinoma

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Taewoo Yang ◽  
Yegyun Choi ◽  
Jae Won Joh ◽  
Steve K. Cho ◽  
Dae-Shick Kim ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Proliferating Cell Nuclear Antigen ◽  
Prognostic Value ◽  
Nuclear Antigen ◽  
Survival Outcomes ◽  
P53 Expression ◽  
Immunohistochemical Markers ◽  
Prognostic Utility ◽  
Poor Outcomes ◽  
Proliferating Cell

Background. Hepatocellular carcinoma (HCC) is one of the most common malignant cancers with a poor prognosis. Several commonly investigated immunohistochemical markers in resected HCC have potential prognostic value, but the prognostic utility of p53 expression in HCC has remained elusive. Aim. To evaluate the prognostic value of p53 and p53 phosphorylation at serine 15 (p53 Ser15-P) in patients with HCC. Methods. Surgically resected tumors from 199 HCC patients were analyzed for p21, p53, p53 Ser15-P, and proliferating cell nuclear antigen (PCNA) expression using immunohistochemistry. Results. Stratifying by the expression of p53 Ser15-P (P = 0.016), but not by p53 (P = 0.301), revealed significantly different survival outcomes in patients with HCC. Moreover, our analysis demonstrated that patients who were PCNA-positive and p53 Ser15-P–negative had significantly worse survival outcomes (P = 0.001) than patients who were PCNA-positive and p53 Ser15-P–positive. Conclusions. P53 Ser15-P is associated with poor outcomes in patients with HCC, and this prognostic marker is useful for predicting the survival of patients with PCNA-positive HCC.

Prognostic value of proliferating cell nuclear antigen in parotid gland cancer

2011 ◽  
Vol 269 (4) ◽  
pp. 1225-1232 ◽  
Author(s):  
Markus Stenner ◽  
Ariane Demgensky ◽  
Christoph Molls ◽  
Aline Hardt ◽  
Jan C. Luers ◽  
...  
Keyword(s):  
Parotid Gland ◽  
Proliferating Cell Nuclear Antigen ◽  
Prognostic Value ◽  
Nuclear Antigen ◽  
Parotid Gland Cancer ◽  
Proliferating Cell
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