Some properties of Bomirski Ab amelanotic melanoma cells, which underwent spontaneous melanization in primary cell culture

1985 ◽  
Vol 109 (1) ◽  
pp. 29-37 ◽  
Author(s):  
Andrzej Słomiński
Keyword(s):  
Cell Culture ◽  
Primary Cell Culture ◽  
Melanoma Cells ◽  
Amelanotic Melanoma ◽  
Primary Cell

Rapid melanization of bomirski amelanotic melanoma cells in cell culture

1983 ◽  
Vol 3 (2) ◽  
pp. 189-194 ◽  
Author(s):  
A. Słominski
Keyword(s):  
Cell Culture ◽  
Primary Cell Culture ◽  
Growth Conditions ◽  
Melanoma Cells ◽  
Amelanotic Melanoma ◽  
Primary Cell ◽  
In Vitro Growth

Transfer of Bomirski amelanotic melanoma ceils from in vivo to in vitro growth conditions results in occurrence of rapid melanization in their cytoplasm. The melanized ceils from primary cell culture initiate tumours in hamsters, which do not contain traces of melanin and resemble typical amelanotic melanoma.

Effects of actinomycin D and cycloheximide on the increase in tyrosinase activity of hamster amelanotic

1984 ◽  
Vol 4 (12) ◽  
pp. 1059-1064 ◽  
Author(s):  
A. Słomiñski ◽  
A. Bomirski ◽  
P. W. D. Ścisłowski ◽  
S. Żołnierowicz
Keyword(s):  
Cell Culture ◽  
Primary Cell Culture ◽  
Actinomycin D ◽  
Calf Serum ◽  
Amelanotic Melanoma ◽  
Tyrosinase Activity ◽  
Primary Cell ◽  
Serum Free ◽  
Activation Of Transcription

Tyrosinase activity in the Ab hamster amelanotic melanoma ceils cultured in serum-free Eagle's MEM increased 3 times after 6 h of primary cell culture. This increase was inhibited completely by cycloheximide, while actinomycin D had no effect on this process. After 24 h of culture in MEM with calf serum, further increase of the tyrosinase activity was inhibited by both cycloheximide and actinomycin D. The data presented may indicate that the increase of tyrosinase activity in the primary cell culture of the Ab melanoma is due initially to the unblocking of translation and later to the activation of transcription of the gene controlling the enzyme.

The role of ER stress for the pathogenesis of SCA3 in primary cell culture experiment

2007 ◽  
Vol 34 (S 2) ◽  
Author(s):  
C Funke ◽  
J Hübener ◽  
H Wolburg ◽  
T Schmidt ◽  
H Toresson ◽  
...  
Keyword(s):  
Cell Culture ◽  
Er Stress ◽  
Primary Cell Culture ◽  
Primary Cell ◽  
Culture Experiment ◽  
Cell Culture Experiment

scholarly journals Gene Expression Profiling of Extracellular Matrix as an Effector of Human Hepatocyte Phenotype in Primary Cell Culture

2007 ◽  
Vol 97 (2) ◽  
pp. 384-397 ◽  
Author(s):  
J. L. Page ◽  
M. C. Johnson ◽  
K. M. Olsavsky ◽  
S. C. Strom ◽  
H. Zarbl ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cell Culture ◽  
Extracellular Matrix ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Primary Cell Culture ◽  
Human Hepatocyte ◽  
Primary Cell
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