The effects of low concentrations of actinomycin D upon nucleic acid synthesis in different cell types

1973 ◽  
Vol 29 (11) ◽  
pp. 1390-1392
Author(s):  
A. Özalpan
Keyword(s):  
Nucleic Acid ◽  
Actinomycin D ◽  
Cell Types ◽  
Acid Synthesis ◽  
Nucleic Acid Synthesis ◽  
Low Concentrations ◽  
Different Cell Types

The relative rates of synthesis of DNA, sRNA and rRNA in the endodermal region and other parts of Xenopus laevis embryos

Development ◽  
1968 ◽  
Vol 19 (3) ◽  
pp. 363-385
Author(s):  
H. R. Woodland ◽  
J. B. Gurdon
Keyword(s):  
Nucleic Acid ◽  
Xenopus Laevis ◽  
Nucleic Acids ◽  
Cell Types ◽  
Acid Synthesis ◽  
Nucleic Acid Synthesis ◽  
Direct Measure ◽  
Cell Type ◽  
Different Cell Types ◽  
Xenopus Laevis Embryos

The onset and rates of synthesis of the major classes of nucleic acids have been extensively studied during the development of whole frog embryos (reviews by Brown, 1965; Gurdon, 1967a). Such information is of interest because nucleic acids are the immediate products of genes, and their rates of synthesis therefore provide a direct measure of changes in gene activity. To date nucleic acid synthesis in parts of frog embryos has been analysed mainly by methods which do not distinguish different classes of RNA (e.g. Bachvarova & Davidson, 1966; Flickinger, Miyagi, Moser & Rollins, 1967). Since embryos consist of many different cell types, it is important to know to what extent the pattern of nucleic acid synthesis observed in the whole embryo is true for its individual regions, and in particular for one differentiating cell type.

Effect of Actinomycin D on Cellular Nucleic Acid Synthesis and Virus Production

Science ◽  
1961 ◽  
Vol 134 (3478) ◽  
pp. 556-557 ◽  
Author(s):  
E. Reich ◽  
R. M. Franklin ◽  
A. J. Shatkin ◽  
E. L. Tatum
Keyword(s):  
Nucleic Acid ◽  
Actinomycin D ◽  
Virus Production ◽  
Acid Synthesis ◽  
Nucleic Acid Synthesis

scholarly journals Effect of Actinomycin D and 2-Thiouracil on Floral Induction and Nucleic Acid Synthesis in the Bud in Chenopodium Amaranticolor

1966 ◽  
Vol 19 (6) ◽  
pp. 967 ◽  
Author(s):  
JD Watson ◽  
REF Matthews
Keyword(s):  
Nucleic Acid ◽  
Actinomycin D ◽  
Dark Period ◽  
Floral Induction ◽  
Acid Synthesis ◽  
Nucleic Acid Synthesis ◽  
Floral Initiation ◽  
Dark Cycle ◽  
Chenopodium Amaranticolor ◽  
Floral Differentiation

Actinomycin D and 2-thiouracil inhibit floral initiation in C. amaranticolor when applied to plants before the end of the inductive dark period. Actinomycin D does not suppress floral differentiation if it is applied to plants more than 48 hr after the inductive dark cycle, whereas 2-thiouracil retains its ability to interfere with floral differentiation when applied to plants several days after the inductive dark period.

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