Proteus mirabilis as a cause of recurrent lung infection in a cystic fibrosis patient

1990 ◽  
Vol 9 (3) ◽  
pp. 234-235 ◽  
Author(s):  
M. Ojeda-Vargas ◽  
A. Pacheco ◽  
M. Elia ◽  
R. Villaverde ◽  
F. Baquero
Keyword(s):  
Cystic Fibrosis ◽  
Cystic Fibrosis Patient ◽  
Proteus Mirabilis ◽  
Lung Infection

Chronic Lung Infection Caused by Trichosporon mycotoxinivorans and Trichosporon mucoides in an Immunocompetent Cystic Fibrosis Patient

2016 ◽  
Vol 52 (7) ◽  
pp. 400 ◽  
Author(s):  
Francisco de Borja Martínez Muñiz ◽  
María Martínez Redondo ◽  
Concepción Prados Sánchez ◽  
Julio García Rodríguez
Keyword(s):  
Cystic Fibrosis ◽  
Cystic Fibrosis Patient ◽  
Lung Infection ◽  
Chronic Lung Infection

Unorthodox long-term aerosolized ampicillin use for methicillin-susceptible Staphylococcus aureus lung infection in a cystic fibrosis patient

2009 ◽  
Vol 44 (5) ◽  
pp. 512-515 ◽  
Author(s):  
Luis Máiz ◽  
Adelaida Lamas ◽  
Ana Fernández-Olmos ◽  
Lucrecia Suárez ◽  
Rafael Cantón
Keyword(s):  
Cystic Fibrosis ◽  
Staphylococcus Aureus ◽  
Cystic Fibrosis Patient ◽  
Lung Infection

scholarly journals A Case of Phage Therapy against Pandrug-Resistant Achromobacter xylosoxidans in a 12-Year-Old Lung-Transplanted Cystic Fibrosis Patient

Viruses ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 60
Author(s):  
David Lebeaux ◽  
Maia Merabishvili ◽  
Eric Caudron ◽  
Damien Lannoy ◽  
Leen Van Simaey ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Cystic Fibrosis Patient ◽  
Phage Therapy ◽  
Lung Infection ◽  
Achromobacter Xylosoxidans ◽  
Resistant Bacteria ◽  
Low Grade ◽  
First Case ◽  
Phage Receptor ◽  
Airway Colonization

Bacteriophages are a promising therapeutic strategy among cystic fibrosis and lung-transplanted patients, considering the high frequency of colonization/infection caused by pandrug-resistant bacteria. However, little clinical data are available regarding the use of phages for infections with Achromobacter xylosoxidans. A 12-year-old lung-transplanted cystic fibrosis patient received two rounds of phage therapy because of persistent lung infection with pandrug-resistant A. xylosoxidans. Clinical tolerance was perfect, but initial bronchoalveolar lavage (BAL) still grew A. xylosoxidans. The patient’s respiratory condition slowly improved and oxygen therapy was stopped. Low-grade airway colonization by A. xylosoxidans persisted for months before samples turned negative. No re-colonisation occurred more than two years after phage therapy was performed and imipenem treatment was stopped. Whole genome sequencing indicated that the eight A. xylosoxidans isolates, collected during phage therapy, belonged to four delineated strains, whereby one had a stop mutation in a gene for a phage receptor. The dynamics of lung colonisation were documented by means of strain-specific qPCRs on different BALs. We report the first case of phage therapy for A. xylosoxidans lung infection in a lung-transplanted patient. The dynamics of airway colonization was more complex than deduced from bacterial culture, involving phage susceptible as well as phage resistant strains.

scholarly journals Proteomic Profiling of Burkholderia cenocepacia Clonal Isolates with Different Virulence Potential Retrieved from a Cystic Fibrosis Patient during Chronic Lung Infection

PLoS ONE ◽  
2013 ◽  
Vol 8 (12) ◽  
pp. e83065 ◽  
Author(s):  
Andreia Madeira ◽  
Sandra C. dos Santos ◽  
Pedro M. Santos ◽  
Carla P. Coutinho ◽  
Jean Tyrrell ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Cystic Fibrosis Patient ◽  
Lung Infection ◽  
Burkholderia Cenocepacia ◽  
Proteomic Profiling ◽  
Virulence Potential ◽  
Chronic Lung Infection

scholarly journals Anti-pseudomonad Activity of Manuka Honey and Antibiotics in a Specialized ex vivo Model Simulating Cystic Fibrosis Lung Infection

2019 ◽  
Vol 10 ◽  
Author(s):  
Aled E. L. Roberts ◽  
Lydia C. Powell ◽  
Manon F. Pritchard ◽  
David W. Thomas ◽  
Rowena E. Jenkins
Keyword(s):  
Cystic Fibrosis ◽  
Ex Vivo ◽  
Lung Infection ◽  
Cystic Fibrosis Lung ◽  
Manuka Honey ◽  
Ex Vivo Model
Sign in / Sign up

Export Citation Format

Share Document