Interrelationships between serum 25-hydroxycholecalciferol, serum parathyroid hormone and morphometric bone changes in anticonvulsant osteomalacia. Therapeutic effect of vitamin D2

1976 ◽  
Vol 22 (S1) ◽  
pp. 473-478 ◽  
Author(s):  
F. Melsen ◽  
L. Mosekilde ◽  
M. S. Christensen ◽  
B. Lund ◽  
O. H. Sørensen
Keyword(s):  
Parathyroid Hormone ◽  
Therapeutic Effect ◽  
Vitamin D2 ◽  
Serum Parathyroid Hormone ◽  
Bone Changes ◽  
25 Hydroxycholecalciferol

THE INTERRELATIONSHIPS BETWEEN SERUM 25-HYDROXYCHOLECALCIFEROL, SERUM PARATHYROID HORMONE AND BONE CHANGES IN ANTICONVULSANT OSTEOMALACIA

1977 ◽  
Vol 84 (3) ◽  
pp. 559-565 ◽  
Author(s):  
Leif Mosekilde ◽  
Merete Sanvig Christensen ◽  
Birger Lund ◽  
Ole Helmer Sorensen ◽  
Flemming Melsen
Keyword(s):  
Vitamin D ◽  
Parathyroid Hormone ◽  
Dietary Vitamin ◽  
Serum Parathyroid Hormone ◽  
Serum Ipth ◽  
Vitamin D Intake ◽  
Bone Changes ◽  
The Mean ◽  
Dietary Vitamin D ◽  
25 Hydroxycholecalciferol

ABSTRACT Serum 25-hydroxycholecalciferol (25-HCC) and serum parathyroid hormone (iPTH) were measured in 59 randomly selected adult epileptic outpatients receiving chronic anticonvulsant therapy. Quantitative morphometric analysis of iliac crest biopsies was performed. A mild degree of osteomalacia was found which was inversely correlated to dietary vitamin D intake. Serum 25-HCC was reduced in the epileptic patients compared to a control group, although dietary intake of vitamin D was higher than the mean daily intake in the Danish population. Serum 25-HCC was positively correlated to dietary vitamin D intake, but not correlated to the severity of bone changes, indicating that other factors than circulating 25-HCC are responsible for the development of anticonvulsant osteomalacia. Serum 25-HCG was inversely correlated to serum iPTH in patients with a low dietary calcium intake. The mean value of serum iPTH was not increased, and there was no correlation between serum iPTH and bone morphometry.

scholarly journals 5: Congenital rickets a premature infant: evolution of serum parathyroid hormone (iPTH) and plasma 25 hydroxycholecalciferol (25 OH CC)

1976 ◽  
Vol 10 (10) ◽  
pp. 874-874
Author(s):  
L Sann ◽  
L David ◽  
A Frederich ◽  
M Bethendd ◽  
R Francois
Keyword(s):  
Parathyroid Hormone ◽  
Premature Infant ◽  
Serum Parathyroid Hormone ◽  
Congenital Rickets ◽  
25 Hydroxycholecalciferol

Evaluation of intact serum parathyroid hormone (PTH 1-84) in the diagnosis of disorders of calcium metabolism

1988 ◽  
Vol 117 (4_Suppl) ◽  
pp. S64-S65
Author(s):  
K. KRUSE ◽  
U. KRACHT ◽  
K. WOHLFART ◽  
U. KRUSE
Keyword(s):  
Parathyroid Hormone ◽  
Calcium Metabolism ◽  
Serum Parathyroid Hormone

scholarly journals Low serum parathyroid hormone is a risk factor for peritonitis episodes in incident peritoneal dialysis patients: a retrospective study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Yuqi Yang ◽  
Jingjing Da ◽  
Yi Jiang ◽  
Jing Yuan ◽  
Yan Zha
Keyword(s):  
Risk Factor ◽  
Peritoneal Dialysis ◽  
Parathyroid Hormone ◽  
Proportional Hazard ◽  
Serum Parathyroid Hormone ◽  
Cox Proportional Hazard ◽  
Cox Proportional Hazard Regression ◽  
Gram Negative Organisms ◽  
Serum Pth

Abstract Background Serum parathyroid hormone (PTH) levels have been reported to be associated with infectious mortality in peritoneal dialysis (PD) patients. Peritonitis is the most common and fatal infectious complication, resulting in technique failure, hospital admission and mortality. Whether PTH is associated with peritonitis episodes remains unclear. Methods We examined the association of PTH levels and peritonitis incidence in a 7-year cohort of 270 incident PD patients who were maintained on dialysis between January 2012 and December 2018 using Cox proportional hazard regression analyses. Patients were categorized into three groups by serum PTH levels as follows: low-PTH group, PTH < 150 pg/mL; middle-PTH group, PTH 150-300 pg/mL; high-PTH group, PTH > 300 pg/mL. Results During a median follow-up of 29.5 (interquartile range 16–49) months, the incidence rate of peritonitis was 0.10 episodes per patient-year. Gram-positive organisms were the most common causative microorganisms (36.2%), and higher percentage of Gram-negative organisms was noted in patients with low PTH levels. Low PTH levels were associated with older age, higher eGFR, higher hemoglobin, calcium levels and lower phosphate, alkaline phosphatase levels. After multivariate adjustment, lower PTH levels were identified as an independent risk factor for peritonitis episodes [hazard ratio 1.643, 95% confidence interval 1.014–2.663, P = 0.044]. Conclusions Low PTH levels are independently associated with peritonitis in incident PD patients.

Circulating Parathyroid Hormone and Dihydroxylated Vitamin D Metabolites after Oral 25 Hydroxycholecalciferol in Infantile Rickets

1982 ◽  
Vol 14 (09) ◽  
pp. 503-504 ◽  
Author(s):  
E. Mallet ◽  
T. Nguyen ◽  
M. Garabedian ◽  
J. Bassuyau
Keyword(s):  
Vitamin D ◽  
Parathyroid Hormone ◽  
Vitamin D Metabolites ◽  
25 Hydroxycholecalciferol

scholarly journals Altered diurnal regulation of blood ionized calcium and serum parathyroid hormone concentrations during parenteral nutrition

2000 ◽  
Vol 71 (2) ◽  
pp. 560-568 ◽  
Author(s):  
William G Goodman ◽  
Sudipta Misra ◽  
Johannes D Veldhuis ◽  
Anthony A Portale ◽  
He-Jing Wang ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Parenteral Nutrition ◽  
Ionized Calcium ◽  
Serum Parathyroid Hormone ◽  
Diurnal Regulation

Relation of Serum Parathyroid Hormone to Cognitive Function in Elderly Females

1989 ◽  
pp. 329-334
Author(s):  
S. Morimoto ◽  
F. Masugi ◽  
T. Hironaka ◽  
T. Shiraishi ◽  
K. Itoh ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Cognitive Function ◽  
Serum Parathyroid Hormone

scholarly journals Метаболічний профіль крові корів, хворих на післяродову гіпокальціємію

2013 ◽  
pp. 76-80
Author(s):  
Л. Л. Юськів ◽  
В. В. Влізло
Keyword(s):  
Fatty Acids ◽  
Alkaline Phosphatase ◽  
Parathyroid Hormone ◽  
Total Protein ◽  
Clinical Signs ◽  
Inorganic Phosphorus ◽  
Total Calcium ◽  
25 Hydroxycholecalciferol

Проведено дослідження вмісту 25-гідроксихолекальциферолу (25-ОНD3), паратиреоїдного гормону (ПТГ) та кальцитоніну (КТ), а також кальцію загального, зв'язаного з білком та ультрафільтрувального, неорганічного фосфору, маґнію, активності лужної фосфатази, неетерифікованих жирних кислот (НЕЖК), глюкози і білка у крові корів, хворих на післяродову гіпокальціємію. Встановлено, що у крові корів із клінічними ознаками післяродової гіпокальціємії вміст 25-ОНD3 був вищим, а вміст ПТГ і КТ – нижчим, порівняно зі здоровими коровами в 1–2-й день після отелення. Водночас у крові корів, хворих на післяродову гіпо-кальціємію, знижується вміст загального, білокзв’язаного та ультрафільтрувального кальцію, неорганічного фосфору, глюкози, загального білка й підвищується кількість НЕЖК, маґнію, а також активність лужної фосфатази. It was researched the content of 25-hydroxycholecalciferol (25-OND3), parathyroid hormone (PTH) and calcitonin (CT) and total calcium bounded with the protein and ultrafiltered inorganic phosphorus, magnesium, alkaline phosphatase, nonetherified fatty acids (NEFA), glucose and protein in the blood of cows suffering from postpartum hypocalcemia. It was found that in the blood of cows with clinical signs of postpartum hypocalcemia ,25- OHD3 content was higher, but the content of PTH and CT - lower in coparisant with healthy cows within 1-2 days after calving. However, in the blood of cows suffering from postpartum hypocalcemia was decreasing concentration of total, protein-linked and ultrafiltrates calcium, inorganic phosphorus, glucose, total protein and was increasing concentration of NEFA, magnesium and activity of alkaline phosphatase.

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