High incidence of obesity and elevated serum immunoreactive insulin level in patients with paravertebral ligamentous ossification: A relationship to the development of ectopic ossification

1989 ◽  
Vol 7 (1) ◽  
pp. 17-21 ◽  
Author(s):  
Yasuhiro Takeuchi ◽  
Toshio Matsumoto ◽  
Yoh Takuwa ◽  
Yuichi Hoshino ◽  
Takahide Kurokawa ◽  
...  

1977 ◽  
Vol 74 (2) ◽  
pp. 231-241 ◽  
Author(s):  
YVONNE MANGNALL ◽  
ANNE SMYTHE ◽  
D. N. SLATER ◽  
GILLIAN R. MILNER ◽  
R. D. G. MILNER ◽  
...  

Intraperitoneal transplantation of collagenase-digested, isogeneic, neonatal rat pancreatic tissue successfully reversed streptozotocin-induced diabetes in 77% of recipients. The low serum immunoreactive insulin, hyperglycaemia, glycosuria and weight loss, characteristic of the diabetic animal, were corrected and the reduced activities of hepatic glucokinase and pyruvate kinase, and the low glycogen concentration of the liver of diabetic rats were restored to normal. Forty-three per cent of the successfully transplanted rats became normoglycaemic within 1 month of transplantation whereas 57% took from 1 to 6 months to achieve normoglycaemia and displayed a mild glucose intolerance when subjected to a glucose load. The rats which had not become normoglycaemic 6 months after transplantation showed some amelioration of the diabetic state, as shown by increased serum immunoreactive insulin and hepatic glycogen concentration and a slow weight gain compared with diabetic controls.



1974 ◽  
Vol 27 (1) ◽  
pp. 22-28 ◽  
Author(s):  
Ralph W. Fenderson ◽  
Ignacy Sekowski ◽  
N. Chandra Mohan ◽  
Stanley Deutsch ◽  
Fred Benjamin ◽  
...  


Diabetes ◽  
1971 ◽  
Vol 20 (6) ◽  
pp. 410-415 ◽  
Author(s):  
W. G. Ryan ◽  
T. B. Schwartz ◽  
A. F. Nibbe


The Lancet ◽  
1966 ◽  
Vol 287 (7435) ◽  
pp. 465-467 ◽  
Author(s):  
PeterM. Crockford ◽  
RonaldJ. Harbeck ◽  
RobertH. Williams


1985 ◽  
Vol 74 (s318) ◽  
pp. 127-133 ◽  
Author(s):  
P. LAUTALA ◽  
H. K. ÅKERBLOM ◽  
J. VIIKARI ◽  
K. LOUHIVUORI ◽  
M. UHARI ◽  
...  


1970 ◽  
Vol 2 (03) ◽  
pp. 157-160 ◽  
Author(s):  
A. Renauld ◽  
J. E. Pinto ◽  
A. Christensen ◽  
R. Sverdlik ◽  
V. Foglia


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