Enhancement of the immobilization and discrimination of DNA probe on a biosensor using gold nanoparticles

This work described an ultrasensitive fluorescent sensor for sequence-specific recognition of dsDNA based on the quenching of gold nanoparticles (AuNPs) to a fluorophore labeled DNA probe.

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Designing dna probe from hpv 18 and 58 in e6 region for sensing element in the development of genosensor based gold nanoparticles

Biotechnology and Applied Biochemistry ◽

10.1002/bab.2260 ◽

2021 ◽

Author(s):

F. Nadhirah Jaapar ◽

N.A. Parmin ◽

N. Hamidah A Halim ◽

Uda Hashim ◽

Subash C.B. Gopinath ◽

...

Keyword(s):

Gold Nanoparticles ◽

Dna Probe ◽

Sensing Element ◽

Hpv 18

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An organic electrochemical transistor for determination of microRNA21 using gold nanoparticles and a capture DNA probe

Microchimica Acta ◽

10.1007/s00604-018-2944-x ◽

2018 ◽

Vol 185 (9) ◽

Cited By ~ 7

Author(s):

Jing Peng ◽

Tao He ◽

Yulian Sun ◽

Yawen Liu ◽

Qianqian Cao ◽

...

Keyword(s):

Gold Nanoparticles ◽

Dna Probe ◽

Electrochemical Transistor

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Catalytic signal amplification of gold nanoparticles combining with conformation-switched hairpin DNA probe for hepatitis C virus quantification

Chemical Communications ◽

10.1039/c2cc33635a ◽

2012 ◽

Vol 48 (63) ◽

pp. 7877 ◽

Cited By ~ 21

Author(s):

Wen Li ◽

Ping Wu ◽

Hui Zhang ◽

Chenxin Cai

Keyword(s):

Gold Nanoparticles ◽

Hepatitis C Virus ◽

Hepatitis C ◽

Signal Amplification ◽

Dna Probe ◽

Hairpin Dna ◽

Virus Quantification

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Ultrastructural analysis of the spatial distribution of MRNA

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100123167 ◽

1992 ◽

Vol 50 (1) ◽

pp. 552-553

Author(s):

Gary Bassell ◽

Robert H. Singer

Keyword(s):

Electron Microscopy ◽

Spatial Distribution ◽

In Situ Hybridization ◽

High Resolution ◽

Nucleic Acids ◽

Colloidal Gold ◽

Dna Probe ◽

Nucleotide Analogs ◽

Gold Particles

We have been investigating the spatial distribution of nucleic acids intracellularly using in situ hybridization. The use of non-isotopic nucleotide analogs incorporated into the DNA probe allows the detection of the probe at its site of hybridization within the cell. This approach therefore is compatible with the high resolution available by electron microscopy. Biotinated or digoxigenated probe can be detected by antibodies conjugated to colloidal gold. Because mRNA serves as a template for the probe fragments, the colloidal gold particles are detected as arrays which allow it to be unequivocally distinguished from background.

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