Frax score calculations in postmenopausal women with subclinical hypothyroidism

HORMONES ◽  
2013 ◽  
Vol 12 (3) ◽  
pp. 439-448 ◽  
Author(s):  
Snezana Polovina ◽  
Vera Popovic ◽  
Leonidas Duntas ◽  
Natasa Milic ◽  
Dragan Micic
Keyword(s):  
Postmenopausal Women ◽  
Subclinical Hypothyroidism ◽  
Frax Score

The FRAX score in postmenopausal women with subclinical hyperthyroidism

2014 ◽  
Author(s):  
Snezana Polovina ◽  
Vera Popovic-Brkic ◽  
Dragan Micic ◽  
Natasa Milic ◽  
Mirjana Sumarac-Dumanovic ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Subclinical Hyperthyroidism ◽  
Frax Score

scholarly journals Subclinical Hypothyroidism and Risk for Incident Myocardial Infarction Among Postmenopausal Women

2013 ◽  
Vol 98 (6) ◽  
pp. 2308-2317 ◽  
Author(s):  
Vicky A. LeGrys ◽  
Michele Jonsson Funk ◽  
Carol E. Lorenz ◽  
Ayush Giri ◽  
Rebecca D. Jackson ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Postmenopausal Women ◽  
Subclinical Hypothyroidism

l-Thyroxine prevents the bone-conserving effect of HRT in postmenopausal women with subclinical hypothyroidism

1999 ◽  
Vol 13 (3) ◽  
pp. 196-201 ◽  
Author(s):  
A. Pines ◽  
I. Dotan ◽  
U. Tabori ◽  
Y. Villa ◽  
V. Mijatovic ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Subclinical Hypothyroidism

scholarly journals Subclinical Hypothyroidism and Risk for Incident Ischemic Stroke Among Postmenopausal Women

Thyroid ◽  
2014 ◽  
Vol 24 (8) ◽  
pp. 1210-1217 ◽  
Author(s):  
Ayush Giri ◽  
Todd L. Edwards ◽  
Vicky A. LeGrys ◽  
Carol E. Lorenz ◽  
Michele Jonsson Funk ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Postmenopausal Women ◽  
Subclinical Hypothyroidism

Insulin Resistance Syndrome Associated with Subclinical Hypothyroidism in Postmenopausal Women

Metabolism ◽  
2021 ◽  
Vol 116 ◽  
pp. 154517
Author(s):  
Kostitska Iryna ◽  
Zherdova Nadiya ◽  
Basiuha Iryna ◽  
Zhurakivskiy Viktor ◽  
Zhurakivska Oksana
Keyword(s):  
Insulin Resistance ◽  
Postmenopausal Women ◽  
Subclinical Hypothyroidism ◽  
Insulin Resistance Syndrome

scholarly journals Status of Thyroid Disorder among the Thyroid Function Test Samples Received in a Laboratory among Postmenopausal Women: A Descriptive Cross-sectional Study

2021 ◽  
Vol 59 (234) ◽  
Author(s):  
Manoranjan Shrestha ◽  
Reshmi Shrestha
Keyword(s):  
Postmenopausal Women ◽  
Thyroid Function ◽  
Subclinical Hypothyroidism ◽  
Thyroid Dysfunction ◽  
Thyroid Function Test ◽  
Cross Sectional Study ◽  
Reference Laboratory ◽  
Sectional Study ◽  
Cross Sectional ◽  
Function Test

Introduction: Thyroid dysfunction prevalence is high in females worldwide which increases with age. Postmenopausal and elderly women are particularly at risk of developing comorbidities and mortality related to thyroid dysfunction. We aimed to study the prevalence of thyroid dysfunction in postmenopausal women in the National Reference Laboratory of Nepal. Methods: A descriptive cross-sectional study was conducted in National Reference Laboratory from January 2019 to June 2019 including postmenopausal females, ≥49 years. The database of thyroid function test result was used for statistical analysis and proportion of thyroid dysfunction was calculated. The data was collected after approval from the institutional review committee. Statistical Package for Social Sciences version 21 was used to study descriptive data. Results: Out of a total of 160 postmenopausal females with thyroid function tests, 71 (44.4%) had thyroid dysfunction. Subclinical hypothyroidism was the frequently occurring thyroid dysfunction 51 (32%) followed by subclinical hyperthyroidism 13 (8%), hypothyroidism 3 (2%) and hyperthyroidism 3 (2%). In our study population, thyroid dysfunction peaked at 49 to 58 years of age interval 53 (33.1%) and subclinical hypothyroidism was the most frequent form 38 (23.7%). Conclusions: Subclinical hypothyroidism was the common thyroid dysfunction in postmenopausal age which peaked at 49 to 58 years of age group. Early postmenopausal females are predisposed to increased risk of comorbidities (cardiovascular disease, osteoporosis with high fracture, depression) which could be exacerbated with thyroid dysfunction; therefore awareness of thyroid dysfunction prevalence and thyroid screening for early management seems appropriate in Nepalese postmenopausal women.

scholarly journals Performance of FRAX in Predicting Fractures in US Postmenopausal Women with Varied Race and Genetic Profiles

2020 ◽  
Vol 9 (1) ◽  
pp. 285 ◽  
Author(s):  
Qing Wu ◽  
Xiangxue Xiao ◽  
Yingke Xu
Keyword(s):  
African American ◽  
African American Women ◽  
Postmenopausal Women ◽  
Assessment Tool ◽  
Genetic Risk Score ◽  
Fracture Probability ◽  
Genetic Profile ◽  
Mineral Density ◽  
Frax Score ◽  
Whi Study

Background: Whether the Fracture Risk Assessment Tool (FRAX) performed differently in estimating the 10-year fracture probability in women of different genetic profiling and race remained unclear. Methods: The genomic data in the Women’s Health Initiative (WHI) study was analyzed (n = 23,981). The genetic risk score (GRS) was calculated from 14 fracture-associated single nucleotide polymorphisms (SNPs) for each participant. FRAX without bone mineral density (BMD) was used to estimate fracture probability. Results: FRAX significantly overestimated the risk of major osteoporotic fracture (MOF) in the WHI study. The most significant overestimation was observed in women with low GRS (predicted/observed ratio (POR): 1.61, 95% CI: 1.45–1.79) specifically Asian women (POR: 3.5, 95% CI 2.48–4.81) and in African American women (POR: 2.59, 95% CI: 2.33–2.87). Compared to the low GRS group, the 10-year probability of MOF adjusted for the FRAX score was 21% and 30% higher in the median GRS group and high GRS group, respectively. Asian, African American, and Hispanic women respectively had a 78%, 76%, and 56% lower hazard than Caucasian women after the FRAX score was adjusted. The results were similar for hip fractures. Conclusions: Our study suggested the FRAX performance varies significantly by both genetic profile and race in postmenopausal women.

Even mildly elevated TSH is associated with an atherogenic lipid profile in postmenopausal women with subclinical hypothyroidism

2014 ◽  
Vol 40 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Houfa Geng ◽  
Xu Zhang ◽  
Chenggang Wang ◽  
Meng Zhao ◽  
Chunxiao Yu ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Postmenopausal Women ◽  
Subclinical Hypothyroidism ◽  
Atherogenic Lipid Profile ◽  
Atherogenic Lipid
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