In vitro anticancer activity of pyrano[3, 2-c]chromene derivatives with both cell cycle arrest and apoptosis induction

2020 ◽  
Vol 29 (4) ◽  
pp. 617-629
Author(s):  
Ahmed M. El-Agrody ◽  
Ahmed M. Fouda ◽  
Mohammed A. Assiri ◽  
Ahmed Mora ◽  
Tarik E. Ali ◽  
...  
2012 ◽  
Vol 13 (10) ◽  
pp. 5131-5136 ◽  
Author(s):  
Aied M. Alabsi ◽  
Rola Ali ◽  
Abdul Manaf Ali ◽  
Sami Abdo Radman Al-Dubai ◽  
Hazlan Harun ◽  
...  

RSC Advances ◽  
2017 ◽  
Vol 7 (29) ◽  
pp. 17752-17762 ◽  
Author(s):  
Cheng Zhang ◽  
Shang-Hai Lai ◽  
Hui-Hui Yang ◽  
De-Gang Xing ◽  
Chuan-Chuan Zeng ◽  
...  

A new iridium(iii) complex, Ir(ppy)2(FBPIP)]PF6 (Ir-1), was synthesized and characterized. The anticancer activity of the complex was investigated by cytotoxicity in vitro, apoptosis, cell invasion, autophagy, cell cycle arrest and western blot.


2019 ◽  
Vol 43 (22) ◽  
pp. 8566-8579 ◽  
Author(s):  
Miao He ◽  
Qiao-Yan Yi ◽  
Wen-Yao Zhang ◽  
Lan Bai ◽  
Fan Du ◽  
...  

Three new iridium(iii) polypyridyl complexes were synthesized. The cytotoxic activity in vitro and in vivo, apoptosis, cell cycle arrest, mitochondrial membrane potential, ROS and the expression of Bcl-2 family proteins were investigated.


2009 ◽  
Vol 16 (3) ◽  
pp. 403-411 ◽  
Author(s):  
Cheng-ming Sun ◽  
Shi-feng Huang ◽  
Jian-ming Zeng ◽  
Din-bing Liu ◽  
Qing Xiao ◽  
...  

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