Effects of ibuprofen and low-level laser therapy on orthodontic pain by means of the analysis of interleukin 1-beta and substance P levels in the gingival crevicular fluid

2020 ◽  
Author(s):  
Yeşim Kaya ◽  
Özer Alkan ◽  
Ahmet Ufuk Kömüroglu ◽  
Sıddık Keskin
Keyword(s):  
Substance P ◽  
Laser Therapy ◽  
Gingival Crevicular Fluid ◽  
Interleukin 1 ◽  
Low Level Laser Therapy ◽  
Interleukin 1 Beta ◽  
Low Level Laser ◽  
Level Laser ◽  
Orthodontic Pain ◽  
Crevicular Fluid

scholarly journals Gingival crevicular fluid periostin levels in chronic periodontitis patients following nonsurgical periodontal treatment with low-level laser therapy

2016 ◽  
Vol 10 (04) ◽  
pp. 546-550 ◽  
Author(s):  
Dhanangchaayan Kumaresan ◽  
Aruna Balasundaram ◽  
Vanaja Krishna Naik ◽  
Deva Priya Appukuttan
Keyword(s):  
Laser Therapy ◽  
Chronic Periodontitis ◽  
Periodontal Ligament ◽  
Gingival Crevicular Fluid ◽  
Periodontal Treatment ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Crevicular Fluid

ABSTRACT Objective: Periostin is a matricellular protein highly expressed in periosteum, periodontal ligament and is essential for tissue integrity and maturation. It plays a role in collagen fibrillogenesis and is downregulated in periodontal disease. Biostimulation utilizing low-level laser therapy (LLLT) influences periodontal ligament fibroblast proliferation. This study was conducted with the objective of estimating periostin levels in chronic periodontitis (CP) patients following LLLT as an adjunct to root surface debridement (RSD). Materials and Methods: Thirty periodontally healthy participants (Group I) and sixty CP participants were recruited. Based on the therapeutic intervention, CP patients were allocated to either RSD (Group II) or to RSD with LLLT (Group III) group. Clinical parameters and gingival crevicular fluid (GCF) periostin levels were assessed at the baseline and at the 3rd month. Results: Periostin levels were significantly lower in CP patients when compared to healthy individuals at the baseline (P < 0.01). Following nonsurgical periodontal treatment (NSPT), periostin levels significantly increased in both Group II and III, when compared to baseline values (P < 0.001). Comparison of mean periostin levels between both the treatment groups showed a significant increase in LLLT group than RSD at the 3rd month (P < 0.05). Conclusion: Within the limitations of the present study, LLLT application was found to have additional benefits over RSD with respect to clinical periodontal parameters and GCF periostin levels. Moreover, periostin may be used as a possible biomarker to evaluate the outcome following NSPT.

scholarly journals Low-level laser therapy (830 nm) on orthodontic pain: blinded randomized clinical trial

2018 ◽  
Vol 34 (2) ◽  
pp. 281-286 ◽  
Author(s):  
Isabela Parsekian Martins ◽  
Renato Parsekian Martins ◽  
Sergei Godeiro Fernandes Rabelo Caldas ◽  
Ary dos Santos-Pinto ◽  
Peter H. Buschang ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Laser Therapy ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Orthodontic Pain

scholarly journals Effectiveness of Low-Level Laser Therapy in Reducing Orthodontic Pain: A Systematic Review and Meta-Analysis

2017 ◽  
Vol 2017 ◽  
pp. 1-18 ◽  
Author(s):  
Naira Figueiredo Deana ◽  
Carlos Zaror ◽  
Paulo Sandoval ◽  
Nilton Alves
Keyword(s):  
Laser Therapy ◽  
Meta Analysis ◽  
Risk Of Bias ◽  
Low Level Laser Therapy ◽  
Cochrane Library ◽  
Spontaneous Pain ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Orthodontic Pain

Objectives. To assess the effectiveness of low-level laser therapy (LLLT) in reducing orthodontic pain after the application of orthodontic force (OF).Methods. A systematic search was conducted in the MEDLINE, EMBASE, Scopus, Cochrane Library, Web of Science, and EBSCOhost databases. The study included randomized clinical trials (RCT) which analysed the effectiveness of LLLT in reducing orthodontic pain assessed at 24 and 72 hrs after the application of OF. The risk of bias of the eligible trials was assessed using the Cochrane Collaboration’s risk of bias tool. Standard mean difference was calculated and pooled by meta-analysis using random effect models.Results.Of 467 identified articles, 20 RCT were finally included. In the risk of bias assessments, 13 studies presented a high risk, 5 an unclear risk, and 2 a low risk. The meta-analysis showed that in patients treated with laser versus placebo there was a difference in favour of LLLT in spontaneous pain 24 and 72 hrs after the installation of light archwires and spontaneous pain and chewing pain 24 and 72 hrs after the installation of elastomeric separators.Conclusions.LLLT proved to be effective in promoting a reduction in spontaneous and chewing pain after the application of OF; however, the poor quality of the evidence requires these results to be treated with caution.

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