Freiburg Neuropathology Case Conference: A Partially Calcified, Dura-based Tumour of the Frontal Lobe

2013 ◽  
Vol 23 (1) ◽  
pp. 63-68
Author(s):  
C. A. Taschner ◽  
O. Staszewski ◽  
R. Jabbarli ◽  
A. Keuler ◽  
M. Prinz
Keyword(s):  
Author(s):  
J. Metuzals ◽  
D. F. Clapin ◽  
V. Montpetit

Information on the conformation of paired helical filaments (PHF) and the neurofilamentous (NF) network is essential for an understanding of the mechanisms involved in the formation of the primary lesions of Alzheimer's disease (AD): tangles and plaques. The structural and chemical relationships between the NF and the PHF have to be clarified in order to discover the etiological factors of this disease. We are investigating by stereo electron microscopic and biochemical techniques frontal lobe biopsies from patients with AD and squid giant axon preparations. The helical nature of the lesion in AD is related to pathological alterations of basic properties of the nervous system due to the helical symmetry that exists at all hierarchic structural levels in the normal brain. Because of this helical symmetry of NF protein assemblies and PHF, the employment of structure reconstruction techniques to determine the conformation, particularly the handedness of these structures, is most promising. Figs. 1-3 are frontal lobe biopsies.


2019 ◽  
Vol 62 (7) ◽  
pp. 2400-2410
Author(s):  
Laiene Olabarrieta-Landa ◽  
Itziar Benito-Sánchez ◽  
Montserrat Alegret ◽  
Anna Gailhajanet ◽  
Esther Landa Torre ◽  
...  

Purpose The aim of this study was to compare Basque and Catalan bilinguals' performance on the letter verbal fluency test and determine whether significant differences are present depending on the letters used and the language of administration. Method The sample consisted of 87 Spanish monolinguals, 139 Basque bilinguals, and 130 Catalan bilinguals from Spain. Participants completed the letter verbal fluency test using the letters F, A, S, M, R, P, and E. Results Bilinguals scored higher on the letter verbal fluency test when they were tested in Spanish than in Basque or Catalan. No performance differences were found according to native language or dialects within Basque participants. Catalans with Spanish as their native language scored lower on the letter F compared to those who grew up speaking Catalan and Spanish. The suggested letters to use with Basque speakers are A, E, and B; the suggested letters to use with Catalan speakers are P, F, and M; and the suggested letters to use with Spanish speakers are M, R, and P. Conclusion Selecting appropriate stimuli depending on the language of testing is the first crucial step to assess verbal fluency and thus possible frontal lobe functioning impairment.


1995 ◽  
Author(s):  
George E. Abbott ◽  
◽  
Ray William London ◽  
Irving Kirsch

2008 ◽  
Author(s):  
Christopher Immel ◽  
James Hadder ◽  
Michael Knepp ◽  
Chad Stephens ◽  
Ryoichi Noguchi ◽  
...  

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