scholarly journals Optimal insulin regimens in type 2 diabetes mellitus: systematic review and meta-analyses

Diabetologia ◽  
2009 ◽  
Vol 52 (10) ◽  
pp. 1990-2000 ◽  
Author(s):  
D. S. Lasserson ◽  
P. Glasziou ◽  
R. Perera ◽  
R. R. Holman ◽  
A. J. Farmer
2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Tingwei Xia ◽  
Yue Yang ◽  
Weihong Li ◽  
Zhaohui- Tang ◽  
Qingsong Huang ◽  
...  

Objective. Physical activity plays a specific role in the fundamental aspect of diabetes care. It is necessary to develop exercise programs for these patients. The aim of this systematic review is to summarize current evidence regarding the effectiveness of meditative movement in patients with type 2 diabetes. Methods. The following databases were searched: PubMed, CENTRAL, Web of Science, Ovid LWW, and EMBASE. Two independent investigators searched and screened the studies by finding duplications, excluding irrelevant titles and abstracts, and then selecting eligible studies by reviewing full texts. 21 studies fulfilled the inclusion criteria. Meta-analyses were performed on glycated hemoglobin (HbA1c), fasting blood glucose (FBG) and postprandial blood glucose (PPBG), total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and body mass index (BMI). Results. Meta-analyses showed that meditative movements significantly improved FBG, HbA1c, PPBG, TC, LDL-C, and HDL-C. No improvement was found in BMI. Conclusions. The results demonstrated a favorable effect or tendency of meditative movements to improve blood glucose and blood lipid levels in patients with type 2 diabetes mellitus. The special effects of meditative movements in type 2 diabetes mellitus patients need further research.


2015 ◽  
Vol 33 (5) ◽  
pp. 580-591 ◽  
Author(s):  
L. Rehackova ◽  
B. Arnott ◽  
V. Araujo-Soares ◽  
A. A. Adamson ◽  
R. Taylor ◽  
...  

Nutrients ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 1027 ◽  
Author(s):  
José C. Fernández-Cao ◽  
Marisol Warthon-Medina ◽  
Victoria H. Moran ◽  
Victoria Arija ◽  
Carlos Doepking ◽  
...  

Zinc could have a protective role against type 2 diabetes mellitus (T2DM). This systematic review and meta-analysis aimed to evaluate the association between dietary, supplementary, and total zinc intake, as well as serum/plasma and whole blood zinc concentration, and risk of T2DM. Observational studies, conducted on cases of incident diabetes or T2DM patients and healthy subjects that reported a measure of association between zinc exposure and T2DM, were selected. Random effects meta-analyses were applied to obtain combined results. Stratified meta-analyses and meta-regressions were executed to assess sources of heterogeneity, as well as the impact of covariates on the findings. From 12,136 publications, 16 studies were selected. The odds ratio (OR) for T2DM comparing the highest versus lowest zinc intake from diet was 0.87 (95% CI: 0.78–0.98). Nevertheless, no association between supplementary or total zinc intake from both diet and supplementation, and T2DM was observed. A direct relationship was found between serum/plasma zinc levels and T2DM (OR = 1.64, 95% CI: 1.25–2.14). A moderately high dietary zinc intake, in relation to the Dietary Reference Intake, could reduce by 13% the risk of T2DM, and up to 41% in rural areas. Conversely, elevated serum/plasma zinc concentration was associated with an increased risk of T2DM by 64%, suggesting disturbances in zinc homeostasis.


Jurnal NERS ◽  
2020 ◽  
Vol 14 (3) ◽  
pp. 199
Author(s):  
Yulia Kurniawati ◽  
Hurin’in Aisy Baridah ◽  
Made Dian Kusumawati ◽  
Irfan Wabula

Introduction: Type 2 diabetes mellitus (T2DM) is one of the main causes of increasing global health morbidity and mortality for diabetes cases. Increasing the glycemic control in patients with T2DM is not enough if it is only treated with anti-hyperglycemic drugs. Physical exercise is an activity that is planned, structured and carried out to improve health or physical fitness and it is an effective way to improve glycemic control. The aim of this study was to search and review the research on effectiveness of physical exercise on glycemic control in T2DM.Methods: We searched the scientific literature on T2DM and physical exercise in the ScienceDirect, ProQuest, Scopus, Ebsco and Pubmed databases for original research studies and then we reviewed them systematically. Of the 1145 articles retrieved, 14 studies were obtained by the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) methodResults: Aerobic physical exercise improved the glycemic control of T2DM and it was widely used and significant for glycemic control. The schedule of 3 times a week for 60 minutes per session over 2 months was widely used and significant when it came to reducing blood glucose and hemoglobin A1c (HbA1c).Conclusion: This systematic review could be used as evidence when carrying out aerobic physical exercise interventions for the purpose of glycemic control.


Author(s):  
Arwa Aljabali ◽  
Roaa Maghrabi ◽  
Ahmad Shok ◽  
Ghufran Alshawmali ◽  
Abdullah Alqahtani ◽  
...  

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