Sodium butyrate recovers high-fat diet-fed female Wistar rats from glucose dysmetabolism and uric acid-associated cardiac tissue damage

2019 ◽  
Vol 392 (11) ◽  
pp. 1411-1419 ◽  
Author(s):  
Caroline Badejogbin ◽  
Damilare E. Areola ◽  
Kehinde S. Olaniyi ◽  
Oluwaseun A. Adeyanju ◽  
Isaac O. Adeosun
Keyword(s):  
Uric Acid ◽  
Sodium Butyrate ◽  
Tissue Damage ◽  
High Fat Diet ◽  
Wistar Rats ◽  
Cardiac Tissue ◽  
High Fat ◽  
Female Wistar Rats

scholarly journals Sodium butyrate arrests pancreato-hepatic synchronous uric acid and lipid dysmetabolism in high fat diet fed Wistar rats

2021 ◽  
Vol 133 ◽  
pp. 110994
Author(s):  
Oluwaseun A. Adeyanju ◽  
Olabimpe C. Badejogbin ◽  
Damilare E. Areola ◽  
Kehinde S. Olaniyi ◽  
Chinaza Dibia ◽  
...  
Keyword(s):  
Uric Acid ◽  
Sodium Butyrate ◽  
High Fat Diet ◽  
Wistar Rats ◽  
High Fat

Effects of chia (Salvia hispanica L.) on oxidative stress and inflammation in ovariectomized adult female Wistar rats

2019 ◽  
Vol 10 (7) ◽  
pp. 4036-4045 ◽  
Author(s):  
Bárbara Pereira da Silva ◽  
Renata Celi Lopes Toledo ◽  
Marcella Duarte Villas Mishima ◽  
Maria Eliza de Castro Moreira ◽  
Christiane Mileib Vasconcelos ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Adult Female ◽  
High Fat Diet ◽  
Wistar Rats ◽  
Lipid Profiles ◽  
Ovariectomized Rats ◽  
High Fat ◽  
Salvia Hispanica ◽  
Female Wistar Rats ◽  
Salvia Hispanica L

The study investigated the influence of chia consumption on inflammation, oxidative stress, and lipid profiles in female ovariectomized rats fed a high-fat diet.

Amla (Emblica officinalis) improves hepatic and renal oxidative stress and the inflammatory response in hypothyroid female wistar rats fed with a high-fat diet

2018 ◽  
Vol 29 (2) ◽  
pp. 175-184 ◽  
Author(s):  
P. Rajaa Muthu ◽  
Zachariah Bobby ◽  
P. Sankar ◽  
V. Vickneshwaran ◽  
Sajini Elizabeth Jacob
Keyword(s):  
Oxidative Stress ◽  
Inflammatory Response ◽  
High Fat Diet ◽  
Wistar Rats ◽  
Molecular Techniques ◽  
Emblica Officinalis ◽  
High Fat ◽  
Tnf Α ◽  
Female Wistar Rats ◽  
Liver And Kidney

AbstractBackground:We investigated the protective effects of amla (Emblica officinalis) on the pathogenesis of oxidative stress (OS) and inflammatory response in hypothyroid rats fed with a high-fat diet (HFD) as an experimental model of hypothyroidism (HT) with obesity.Methods:A total of 80 female wistar rats (5-months-old) were divided into eight different groups. Propylthiouracil (PTU) and HFD were used to induce the experimental HT and obesity, respectively. The euthyroid and hypothyroid rats were fed either normal chow or HFD with and without amla extract (AE, 100 mg/kg bw/day) for 6 weeks. The blood and tissues, liver and kidney OS and inflammatory parameters were studied using appropriate biochemical and molecular techniques.Results:PTU and HFD per se caused OS and inflammatory response as evidenced by increased plasma MDA, TNF-α, CRP and GPx in association with decreased levels of TAS and reduced glutathione (GSH). The proteomic analysis revealed that the expressions of pERK, pP38, TNF-α, IL6, COX2 and NOX-4 were up-regulated in the liver and kidney of these rats. In addition, all these metabolic derangements were further augmented when HT was followed by the addition of HFD. This suggested that there was a synergism between HT and the intake of HFD on the development of OS and inflammatory response.Conclusions:The treatment with amla fruit extract significantly restored the redox imbalance and inflammatory signaling and ameliorated OS and inflammatory response, suggesting the use of this natural compound as an alternative remedy or adjuvant for the management of metabolic complications concomitant with HT.

scholarly journals Antioxidant and Ameliorative Potential of Aqueous Seed extracts of Delonix regia on High Fat Diet and Streptozotocin Induced Diabetes in Female Wistar Rats

2018 ◽  
Vol 32 (S1) ◽  
Author(s):  
BLESSING MINAOPUNYE ONYEGEME‐OKERENTA ◽  
PHILIP OSEIKHUENMHEN OGBOYE ◽  
COMFORT CHINAZO MONAGO‐IGHORODJE ◽  
IFEOMA NWAMAKA MONAGO
Keyword(s):  
High Fat Diet ◽  
Wistar Rats ◽  
High Fat ◽  
Delonix Regia ◽  
Female Wistar Rats ◽  
Streptozotocin Induced Diabetes ◽  
Seed Extracts

Plantago maxima leaves extract inhibits adipogenic action of a high-fat diet in female Wistar rats

2013 ◽  
Vol 53 (3) ◽  
pp. 831-842 ◽  
Author(s):  
Alexey A. Tinkov ◽  
Olga N. Nemereshina ◽  
Elizaveta V. Popova ◽  
Valentina S. Polyakova ◽  
Viktor A. Gritsenko ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Wistar Rats ◽  
High Fat ◽  
Female Wistar Rats

scholarly journals Response of Cardiac Tissue Oxidative Stress After Aerobic Exercise and Capsaicin Administrations in Rats Fed High-Fat Diet

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Maryam Davaran ◽  
Ahmad Abdi ◽  
Javad Mehrabani ◽  
Asieh Abbassi Daloii
Keyword(s):  
Oxidative Stress ◽  
High Fat Diet ◽  
Wistar Rats ◽  
Cardiac Tissue ◽  
Aerobic Training ◽  
Normal Diet ◽  
High Fat ◽  
Male Wistar Rats ◽  
Oxidative Effects ◽  
Antioxidant Effects

Background: Oxidative stress harms cells and impairs the balance between oxidative and antioxidative factors. Exercise and capsaicin have anti-inflammatory and antioxidant effects, as well as some benefits on the cardiovascular system. Objectives: The aim of the present study was to examine the effect of aerobic training with capsaicin on heart changes oxidative stress in rats fed a high-fat diet (HFD). Methods: In this experimental study, 40 male Wistar rats were fed a normal diet (ND, n = 8) or HFD (n = 32) for 8 weeks. After eight weeks, all rats were divided into five groups: ND, HFD, high-fat diet-training (HFDT), high-fat diet-capsaicin (HFDCap), high-fat diet-training-capsaicin (HFDTCap). Training groups performed a progressive aerobic running program (at 15 - 25 m/min, 30 - 60 min/day, and 5 days/week) on a motor-driven treadmill for eight weeks. Capsaicin (4 mg/kg/day) was administered orally, by gavage, once a day. Results: The results showed significant increase in cardiac SOD, GPx and CAT levels in HFDT (P < 0.001), HFDCap (P < 0.001) and HFDTCap (P < 0.001) groups. Also, a significant increase in the amount of this index was observed in the HFDTCap compared to the HFDT and HFDCap groups (P < 0.05). The level of malondialdehyde (MDA) in all experimental groups was significantly lower than the HFD group (P < 0.001). Conclusions: Exercise and capsaicin improve HFD-induced oxidative stress. Therefore, exercise and capsaicin can be used as an appropriate alternative treatment for obesity and its associated inflammatory and oxidative effects.

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