Plasma Leptin Values in Relation to Bone Mass and Density and to Dynamic Biochemical Markers of Bone Resorption and Formation in Postmenopausal Women

1998 ◽  
Vol 63 (6) ◽  
pp. 456-458 ◽  
Author(s):  
A. Goulding ◽  
R. W. Taylor
Keyword(s):  
Bone Resorption ◽  
Bone Mass ◽  
Postmenopausal Women ◽  
Biochemical Markers ◽  
Plasma Leptin ◽  
Markers Of Bone Resorption

New biochemical markers of bone resorption in the study of postmenopausal osteoporosis

1997 ◽  
Vol 265 (2) ◽  
pp. 225-234 ◽  
Author(s):  
Concepción de la Piedra ◽  
Maria Luisa Traba ◽  
Casimira Dominguez Cabrera ◽  
Manuel Sosa Henríquez
Keyword(s):  
Bone Resorption ◽  
Postmenopausal Osteoporosis ◽  
Biochemical Markers ◽  
Markers Of Bone Resorption

Effects of oral alendronate and intranasal salmon calcitonin on bone mass and biochemical markers of bone turnover in postmenopausal women with osteoporosis

Bone ◽  
1995 ◽  
Vol 17 (4) ◽  
pp. 383-390 ◽  
Author(s):  
S. Adami ◽  
M. Passeri ◽  
S. Ortolani ◽  
M. Broggini ◽  
L. Carratelli ◽  
...  
Keyword(s):  
Bone Mass ◽  
Bone Turnover ◽  
Postmenopausal Women ◽  
Salmon Calcitonin ◽  
Biochemical Markers ◽  
Markers Of Bone Turnover

Evaluation of zygomatic bone region for placement of quad zygomatic implants using CBCT in postmenopausal women

2021 ◽  
Vol 7 (2) ◽  
pp. 48-53
Author(s):  
Neelam Manoj Vaibhav ◽  
Ramesh Amirisetty ◽  
Rajesh Nichenametla ◽  
Gonabhavi Siri Chandana ◽  
Santhi Prathyusha M ◽  
...  
Keyword(s):  
Bone Resorption ◽  
Bone Mass ◽  
Postmenopausal Women ◽  
Bone Volume ◽  
Primary Osteoporosis ◽  
Alveolar Ridge ◽  
Age Group ◽  
Zygomatic Bone ◽  
Zygomatic Implants ◽  
Bone To Implant Contact

Insufficient height and width of the alveolar ridge at the implant site remains with inadequate bone volume following extraction in older age people especially in postmenopausal women. Postmenopausal women are susceptible to primary osteoporosis where more bone resorption than formation is seen resulting in decreased bone mass. Hence the present study aims to evaluate the zygomatic bone region for placement of quad zygomatic implants using CBCT.: A total of 120 CBCT images of female patients who were between the age group of 45 yrs to 65 yrs were taken. The zygomatic bone was evaluated for pneumatisation zones and thickness of zygomatic bone at three different regions i.e., superior, middle and inferior at nine points on zygoma bone along with bone to implant contact (BIC) region using virtual software. The largest thickness in the superior, middle and inferior regions were at Point A2(8.01+/-2.10 mm), Point B2 (7.01+/-1.62 mm), and Point C1 (6.65+/-1.64 mm), respectively. The virtually placed implants at Point A3 (15.92+/-4.16 mm) and Point B2 (12.02+/-3.62 mm) had the highest BICs. : To obtain the largest BICs, results suggested that the posterosuperior region (Point A3) and the centre of zygoma (Point B1) were the optimal places for the placement of quad zygomatic implants.

Different responses of biochemical markers of bone resorption to bisphosphonate therapy in Paget disease

1995 ◽  
Vol 41 (11) ◽  
pp. 1592-1598 ◽  
Author(s):  
A Blumsohn ◽  
K E Naylor ◽  
A M Assiri ◽  
R Eastell
Keyword(s):  
Bone Resorption ◽  
Biochemical Markers ◽  
Type I Collagen ◽  
Bisphosphonate Therapy ◽  
Response To Therapy ◽  
Tartrate Resistant Acid Phosphatase ◽  
Type I ◽  
Paget Disease ◽  
Markers Of Bone Resorption ◽  
Total Alkaline

Abstract We examined the response of different biochemical markers of bone resorption to bisphosphonate therapy (400 mg of etidronate daily for 6 months) in mild Paget disease (n = 14). Urinary markers included hydroxyproline (OHP), total (T) and free (F) pyridinolines (Pyds) determined by HPLC, immunoreactive FPyds, immunoreactive TPyds, and the N- and C-terminal telopeptides of type I collage (NTx, CL). Serum measurements included tartrate-resistant acid phosphatase (TRAcP) and the C-terminal telopeptide of type I collagen (ICTP). ICTP and TRAcP showed a minimal response to therapy (% change at 6 months, -13.1 +/- 6.8 and -6.7 +/- 3.4, respectively). The response was greatest for urinary telopeptides (NTx and CL; % change -75.7 +/- 7.5 and -73.4 +/- 8.9, respectively). The response was somewhat greater for TPyds than for FPyds. We conclude that: (a) ICTP and TRAcP are unreliable indicators of changes in bone turnover; (b) oligopeptide-bound Pyds and telopeptide fragments of type I collagen in urine show a somewhat greater response to therapy than do FPyds and may be more sensitive indicators of bone resorption; and (c) as yet no evidence suggests that these markers are substantially better predictors of the clinical response to therapy than serum total alkaline phosphatase or urinary OHP. There are several problems with the interpretation of these measurements in Paget disease, and the clinical utility of these measurements remains uncertain.

scholarly journals The effect of short-term calcium supplementation on biochemical markers of bone metabolism in healthy young adults

1998 ◽  
Vol 80 (5) ◽  
pp. 437-443 ◽  
Author(s):  
Fiona Ginty ◽  
Albert Flynn ◽  
Kevin D. Cashman
Keyword(s):  
Young Adults ◽  
Bone Resorption ◽  
Bone Mass ◽  
Biochemical Markers ◽  
Calcium Supplementation ◽  
Short Term ◽  
Serum Samples ◽  
Bone Specific Alkaline Phosphatase ◽  
Short Term Study ◽  
Usual Diet

The influence of Ca supplementation of the usual diet for 14d on biochemical markers of bone turnover was investigated in healthy young adults aged 21–26 years. In a crossover study, eighteen subjects (five male and thirteen female) were randomly assigned to their self-selected diet (about 22 mmol Ca/d) or their self-selected diet with a 20 mmol/d Ca supplement (about 40 mmol Ca/d) for 14d followed by crossover to the alternative diet for a further 14d. During each dietary period fasting morning first void urine samples (last 3d) and fasting blood serum samples (morning of twelfth day) were collected. Ca supplementation reduced urinary excretion of pyridinoline (14%) and deoxypyridinoline (16%) (biochemical markers of bone resorption) but had no effect on biochemical markers of bone formation (serum osteocalcin and bone-specific alkaline phosphatase;EC3.1.3.1). It is concluded that Ca supplementation of the usual diet in young adults suppresses bone resorption over a 2-week period. If sustained, this could result in suppression of the bone remodelling rate and an increase in bone mass over time. The findings of this short-term study with a relatively small number of young adults highlight the need for a longer-term intervention study of the effect of increased Ca intake on bone mass in this age group.

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