Long-Term Mortality in Patients Operated for Perforated Peptic Ulcer: Factors Limiting Longevity are Dominated by Older Age, Comorbidity Burden and Severe Postoperative Complications

2016 ◽  
Vol 41 (2) ◽  
pp. 410-418 ◽  
Author(s):  
K. Thorsen ◽  
J. A. Søreide ◽  
K. Søreide
Keyword(s):  
Peptic Ulcer ◽  
Postoperative Complications ◽  
Perforated Peptic Ulcer ◽  
Older Age ◽  
Comorbidity Burden ◽  
Long Term Mortality

scholarly journals Short- and long-term outcomes of infective endocarditis admission in adults: A population-based registry study in Finland

PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0254553
Author(s):  
Elina Ahtela ◽  
Jarmo Oksi ◽  
Tero Vahlberg ◽  
Jussi Sipilä ◽  
Päivi Rautava ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Large Population ◽  
Temporal Trends ◽  
Population Based ◽  
Factors Affecting ◽  
Comorbidity Burden ◽  
Hospital Stays ◽  
Population Based Registry ◽  
Long Term Mortality

Infective endocarditis (IE) is associated with high mortality. However, data on factors associated with length of stay (LOS) in hospital due to IE are scarce. In addition, long-term mortality of more than 1 year is inadequately known. In this large population-based study we investigated age and sex differences, temporal trends, and factors affecting the LOS in patients with IE and in-hospital, 1-year, 5-year and 10-year mortality of IE. Data on patients (≥18 years of age) admitted to hospital due to IE in Finland during 2005–2014 were collected retrospectively from nationwide obligatory registries. We included 2166 patients in our study. Of the patients 67.8% were men. Women were older than men (mean age 63.3 vs. 59.5, p<0.001). The median LOS was 20.0 days in men and 18.0 in women, p = 0.015. In the youngest patients (18–39 years) the median LOS was significantly longer than in the oldest patients (≥80 years) (24.0 vs. 16.0 days, p = 0.014). In-hospital mortality was 10% with no difference between men and women. Mortality was 22.7% at 1 year whereas 5- and 10-year mortality was 37.5% and 48.5%, respectively. The 5-year and 10-year mortality was higher in women (HR 1.18, p = 0.034; HR 1.18, p = 0.021). Both in-hospital and long-term mortality increased significantly with aging and comorbidity burden. Both mortality and LOS remained stable over the study period. In conclusion, men had longer hospital stays due to IE compared to women. The 5- and 10-year mortality was higher in women. The mortality of IE or LOS did not change over time.

scholarly journals Predicting the Amount of Intraperitoneal Fluid Accumulation by Computed Tomography and Its Clinical Use in Patients With Perforated Peptic Ulcer

2014 ◽  
Vol 99 (6) ◽  
pp. 824-829 ◽  
Author(s):  
Toru Ishiguro ◽  
Youichi Kumagai ◽  
Hiroyuki Baba ◽  
Yusuke Tajima ◽  
Hideko Imaizumi ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Peptic Ulcer ◽  
Postoperative Complications ◽  
Ct Scan ◽  
Peritoneal Fluid ◽  
Treatment Decision ◽  
Perforated Peptic Ulcer ◽  
Clinical Parameters ◽  
Treatment Decision Making ◽  
The Relationship

Abstract The correlation between the amount of peritoneal fluid and clinical parameters in patients with perforated peptic ulcer (PPU) has not been investigated. The authors' objective was to derive a reliable formula for determining the amount of peritoneal fluid in patients with PPU before surgery, and to evaluate the correlation between the estimated amount of peritoneal fluid and clinical parameters. We investigated 62 consecutive patients who underwent emergency surgery for PPU, and in whom prediction of the amount of accumulated intraperitoneal fluid was possible by computed tomography (CT) using the methods described by Oriuchi et al. We examined the relationship between the predicted amount of accumulated intraperitoneal fluid and that measured during surgery, and the relationship between the amount of fluid predicted preoperatively or measured during surgery and several clinical parameters. There was a significant positive correlation between the amount of fluid predicted by CT scan and that measured during surgery. When patients with gastric ulcer and duodenal ulcer were analyzed collectively, the predicted amount of intraperitoneal fluid and the amount measured during surgery were each associated with the period from onset until CT scan, perforation size, the Mannheim peritoneal index, and the severity of postoperative complications according to the Clavien–Dindo classification. Our present results suggest that the method of Oriuchi et al is useful for predicting the amount of accumulated intraperitoneal fluid in patients with PPU, and that this would be potentially helpful for treatment decision-making and estimating the severity of postoperative complications.

The excess long-term mortality in peptic ulcer bleeding is explained by nonspecific comorbidity

2014 ◽  
Vol 50 (2) ◽  
pp. 145-152 ◽  
Author(s):  
Stig Borbjerg Laursen ◽  
Jane Møller Hansen ◽  
Jesper Hallas ◽  
Ove B. Schaffalitzky de Muckadell
Keyword(s):  
Peptic Ulcer ◽  
Ulcer Bleeding ◽  
Peptic Ulcer Bleeding ◽  
Long Term Mortality
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