scholarly journals Preclinical efficacy spectrum and pharmacokinetics of ixabepilone

2008 ◽  
Vol 63 (2) ◽  
pp. 201-212 ◽  
Author(s):  
Francis Y. F. Lee ◽  
Richard Smykla ◽  
Kathy Johnston ◽  
Krista Menard ◽  
Kelly McGlinchey ◽  
...  
Keyword(s):  
Preclinical Efficacy

New models of breast and lung cancer bone metastases for preclinical efficacy testing

2016 ◽  
Author(s):  
Mari I. Suominen ◽  
Urs B. Hagemann ◽  
Yvonne Konkol ◽  
Jenni Bernoulli ◽  
Katja M. Fagerlund ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Bone Metastases ◽  
New Models ◽  
Preclinical Efficacy

Preclinical efficacy of PF-04942847, a novel HSP90 inhibitor, in osteosarcoma

2014 ◽  
Author(s):  
Francois Lamoureux ◽  
Marc Baud'Huin ◽  
Benjamin Ory ◽  
Dominique Heymann ◽  
Francoise Redini
Keyword(s):  
Hsp90 Inhibitor ◽  
Preclinical Efficacy

IDO1/TDO dual inhibitor RY103 targets Kyn-AhR pathway and exhibits preclinical efficacy on pancreatic cancer

2021 ◽  
Vol 522 ◽  
pp. 32-43
Author(s):  
Heng Liang ◽  
Tianqi Li ◽  
Xin Fang ◽  
Zikang Xing ◽  
Shengnan Zhang ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Dual Inhibitor ◽  
Preclinical Efficacy

scholarly journals Preclinical efficacy of prexasertib in acute lymphoblastic leukemia

2021 ◽  
Author(s):  
Jason Ostergaard ◽  
Leslie M. Jonart ◽  
Maryam Ebadi ◽  
Stacia L. Koppenhafer ◽  
David J. Gordon ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Lymphoblastic Leukemia ◽  
Preclinical Efficacy

Biological activity and preclinical efficacy of azetidinyl pyridazines as potent systemically-distributed stearoyl-CoA desaturase inhibitors

2011 ◽  
Vol 21 (1) ◽  
pp. 479-483 ◽  
Author(s):  
Elise Isabel ◽  
David A. Powell ◽  
W. Cameron Black ◽  
Chi-Chung Chan ◽  
Sheldon Crane ◽  
...  
Keyword(s):  
Biological Activity ◽  
Stearoyl Coa Desaturase ◽  
Preclinical Efficacy

scholarly journals Preclinical Efficacy and Safety Evaluation of Hematopoietic Stem Cell Gene Therapy in a Mouse Model of MNGIE

2018 ◽  
Vol 8 ◽  
pp. 152-165 ◽  
Author(s):  
Rana Yadak ◽  
Raquel Cabrera-Pérez ◽  
Javier Torres-Torronteras ◽  
Marianna Bugiani ◽  
Joost C. Haeck ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Stem Cell ◽  
Mouse Model ◽  
Safety Evaluation ◽  
Efficacy And Safety ◽  
Hematopoietic Stem ◽  
Preclinical Efficacy ◽  
Cell Gene ◽  
Stem Cell Gene ◽  
Stem Cell Gene Therapy

Long-Term Management of Vascular Access Ports in Nonhuman Primates Used in Preclinical Efficacy and Tolerability Studies

2018 ◽  
Vol 33 (6) ◽  
pp. 493-504 ◽  
Author(s):  
Lucas A. Mutch ◽  
Samuel T. Klinker ◽  
Jody J. Janecek ◽  
Melanie N. Niewinski ◽  
Rachael M. Z. Lee ◽  
...  
Keyword(s):  
Vascular Access ◽  
Nonhuman Primates ◽  
Vascular Access Ports ◽  
Preclinical Efficacy ◽  
Term Management

scholarly journals Safety and Preclinical Efficacy of Aerosol Pioglitazone on Lung Adenoma Prevention in A/J Mice

2016 ◽  
Vol 10 (2) ◽  
pp. 124-132 ◽  
Author(s):  
Donna E. Seabloom ◽  
Arthur R. Galbraith ◽  
Anna M. Haynes ◽  
Jennifer D. Antonides ◽  
Beverly R. Wuertz ◽  
...  
Keyword(s):  
Preclinical Efficacy
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