Tumor-selective cytotoxicity of benzo[c]phenanthridine derivatives from Toddalia asiatica Lam.

2009 ◽  
Vol 65 (4) ◽  
pp. 719-726 ◽  
Author(s):  
Hironori Iwasaki ◽  
Takafumi Okabe ◽  
Kensaku Takara ◽  
Takayoshi Toda ◽  
Masayuki Shimatani ◽  
...  
Keyword(s):  
Selective Cytotoxicity ◽  
Toddalia Asiatica ◽  
Tumor Selective

Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators

1996 ◽  
Vol 7 (5) ◽  
pp. 548-557 ◽  
Author(s):  
Tetsuhiko Shirasaka ◽  
Yuji Shimamato ◽  
Hideyuki Ohshimo ◽  
Masahiro Yamaguchi ◽  
Toshiyuki Kato ◽  
...  
Keyword(s):  
Selective Cytotoxicity ◽  
Tumor Selective

scholarly journals Tumor-selective Cytotoxicity of a Novel Pentadiene Analogue on Human Leukemia/lymphoma Cells

2016 ◽  
Vol 3 (2) ◽  
pp. 138-146 ◽  
Author(s):  
Yahaira Santiago-Vázquez ◽  
Umashankar Das ◽  
Armando Varela-Ramirez ◽  
Sarah T. Baca ◽  
Yoshira Ayala-Marin ◽  
...  
Keyword(s):  
Human Leukemia ◽  
Lymphoma Cells ◽  
Selective Cytotoxicity ◽  
Tumor Selective

Synthesis of deuterated γ-linolenic acid and application for biological studies: metabolic tuning and Raman imaging

2021 ◽  
Author(s):  
Kosuke Dodo ◽  
Ayato Sato ◽  
Yuki Tamura ◽  
Syusuke Egoshi ◽  
Koichi Fujiwara ◽  
...  
Keyword(s):  
Linolenic Acid ◽  
Raman Imaging ◽  
Metabolic Inhibition ◽  
Mechanistic Studies ◽  
Selective Cytotoxicity ◽  
Dual Functional ◽  
Biological Studies ◽  
Tumor Selective

γ-Linolenic acid (GLA) is reported to show tumor-selective cytotoxicity via unidentified mechanisms. We introduced deuterium into GLA as a dual functional tag for metabolic inhibition and Raman imaging and applied for mechanistic studies.

Inhibitors of histone deacetylases induce tumor-selective cytotoxicity through modulating Aurora-A kinase

2007 ◽  
Vol 86 (1) ◽  
pp. 117-128 ◽  
Author(s):  
Jung-Hyun Park ◽  
Hyun-Soon Jong ◽  
Sang Gyun Kim ◽  
Yeonjoo Jung ◽  
Keun-Wook Lee ◽  
...  
Keyword(s):  
Histone Deacetylases ◽  
Aurora A Kinase ◽  
Aurora A ◽  
Selective Cytotoxicity ◽  
Tumor Selective

The oncolytic adenovirus Ad-iREP-2 utilizes p53-dependent rna interference for tumor-selective replication

2008 ◽  
Vol 46 (09) ◽  
Author(s):  
E Gürlevik ◽  
P Schache ◽  
L Zender ◽  
MP Manns ◽  
S Kubicka ◽  
...  
Keyword(s):  
Rna Interference ◽  
Oncolytic Adenovirus ◽  
Tumor Selective

Biocompatible dextran-coated gadolinium-doped cerium oxide nanoparticles as MRI contrast agents with high T1 relaxivity and selective cytotoxicity to cancer cells

2021 ◽  
Author(s):  
Anton Popov ◽  
Maxim Artemovich Abakumov ◽  
Irina Savintseva ◽  
Artem Ermakov ◽  
Nelly Popova ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Mri Contrast Agents ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Selective Cytotoxicity ◽  
Magnetic Resonance Imaging Mri

Gd-based complexes are widely used as magnetic resonance imaging (MRI) contrast agents. The safety of previously approved contrast agents is questionable and is being re-assessed. The main causes of concern...

Tumor-Selective Immune-Active Mild Hyperthermia Associated with Chemotherapy in Colon Peritoneal Metastasis by Photoactivation of Fluorouracil–Gold Nanoparticle Complexes

ACS Nano ◽  
2021 ◽  
Vol 15 (2) ◽  
pp. 3330-3348
Author(s):  
Vladimir Mulens-Arias ◽  
Alba Nicolás-Boluda ◽  
Amandine Pinto ◽  
Alice Balfourier ◽  
Florent Carn ◽  
...  
Keyword(s):  
Gold Nanoparticle ◽  
Peritoneal Metastasis ◽  
Mild Hyperthermia ◽  
Tumor Selective
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