Exercise-induced apoptosis of rat skeletal muscle and the effect of meloxicam

2001 ◽  
Vol 21 (4) ◽  
pp. 133-136 ◽  
Author(s):  
Sule Arslan ◽  
Sevim Erdem ◽  
Aysen Sivri ◽  
Zafer Hasçelik ◽  
Ersin Tan
2008 ◽  
Vol 3 (6) ◽  
pp. 361-372 ◽  
Author(s):  
Vijay Kumar ◽  
Sutapa Mukhopadhy ◽  
Preetmohinder Singh Bedi ◽  
Gurfateh Singh ◽  
Pitchai Balakumar

2012 ◽  
Vol 45 (1) ◽  
pp. 75-80 ◽  
Author(s):  
Liping Zhao ◽  
Wenhui Yan ◽  
Heng Xiang ◽  
Xiaoyang Wang ◽  
Haixuan Qiao

1995 ◽  
Vol 27 (Supplement) ◽  
pp. S37 ◽  
Author(s):  
J. Komulainen ◽  
X. Han ◽  
W. Wang ◽  
S. Koskinen ◽  
V. Kovanen ◽  
...  

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Damian Jozef Flis ◽  
Robert Antoni Olek ◽  
Jan Jacek Kaczor ◽  
Ewa Rodziewicz ◽  
Malgorzata Halon ◽  
...  

The reduction in cholesterol in mitochondria, observed after exercise, is related to the inhibition of mitochondrial swelling. Caveolin-1 (Cav-1) plays an essential role in the regulation of cellular cholesterol metabolism and is required by various signalling pathways. Therefore, the aim of this study was to investigate the effect of prolonged swimming on the mitochondrial Cav-1 concentration; additionally, we identified the results of these changes as they relate to the induction of changes in the mitochondrial swelling and cholesterol in rat skeletal muscle and liver. Male Wistar rats were divided into a sedentary control group and an exercise group. The exercised rats swam for 3 hours and were burdened with an additional 3% of their body weight. After the cessation of exercise, their quadriceps femoris muscles and livers were immediately removed for experimentation. The exercise protocol caused an increase in the Cav-1 concentration in crude muscle mitochondria; this was related to a reduction in the cholesterol level and an inhibition of mitochondrial swelling. There were no changes in rat livers, with the exception of increased markers of oxidative stress in mitochondria. These data indicate the possible role of Cav-1 in the adaptive change in the rat muscle mitochondria following exercise.


2014 ◽  
Vol 593 (3) ◽  
pp. 635-643 ◽  
Author(s):  
Sang Hyun Kim ◽  
Jin Ho Koh ◽  
Kazuhiko Higashida ◽  
Su Ryun Jung ◽  
John O. Holloszy ◽  
...  

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