Myocardial T2 values at 1.5 T by a segmental approach with healthy aging and gender

Author(s):  
Antonella Meloni ◽  
Martini Nicola ◽  
Vincenzo Positano ◽  
Gennaro D’Angelo ◽  
Andrea Barison ◽  
...  
2019 ◽  
Vol 32 (9) ◽  
pp. 1098-1108
Author(s):  
Lydia W. Li ◽  
Sara J. McLaughlin ◽  
Jiaan Zhang

Objectives: We examined the associations of aspects of the immigrant experience—acculturation, neighborhood belonging, and perceived discrimination—with healthy aging in older Chinese Americans and explored whether the associations vary by age and gender. Method: The sample included 3,056 older Chinese Americans. Healthy aging was defined as no disability, no cognitive impairment, and high physical functioning, coded dichotomously (1 = meets all criteria, 0 = otherwise). Acculturation, neighborhood belonging, and perceived discrimination were measured using standardized scales. Results: About 31% of the sample experienced healthy aging. Acculturation was positively associated with healthy aging, with stronger associations in older age and women. A greater sense of neighborhood belonging was associated with higher odds of healthy aging; experiences of discrimination were associated with lower odds. Discussion: Interventions to promote healthy aging in Chinese Americans are needed. Programs that support immigrants with low acculturation levels, strengthen immigrants’ connectedness to their neighbors, and promote inclusiveness may improve population health.


2019 ◽  
Vol 39 (5) ◽  
pp. 545-554
Author(s):  
Allison R. Warren ◽  
Ann M. Steffen

Transgender and gender nonconforming (TGNC) older adults face numerous barriers to healthy aging. These older adults may be less likely to seek out aging-focused services due to fear of discrimination and a lack of culturally competent services. There is a dearth of trainings for aging-focused professionals that would contribute to the development of affirming service environments for TGNC older adults. The current study explores providers’ responses to a professional development training made available nationwide to staff and volunteers of area agencies on aging. Participants’ ( N = 155) reflections on what would be most helpful in their future work with TGNC older adults included requests for role-plays, instructions on creating more inclusive agency documents, increased contact with TGNC older adults, and managing discriminatory language in the workplace. Future directions include creating professional development opportunities that incorporate experiences with and exposure to both other aging-focused providers and TGNC elders.


2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Ruwei Ou ◽  
Wei Song ◽  
Qianqian Wei ◽  
Ke Chen ◽  
Bei Cao ◽  
...  

Objectives. To explore the clinical correlates of nonmotor symptoms (NMS) in progressive supranuclear palsy (PSP) and their differences from healthy controls and patients with Parkinson’s disease (PD).Methods. Twenty-seven PSP patients, 27 age- and gender-matched healthy controls (HC), and 27 age- and gender-matched PD patients were included for this case-control study. NMS were assessed using the Nonmotor Symptoms Scale (NMSS, including 9 domains).Results. All PSP patients reported NMS. The frequency and severity of “sleep/fatigue,” “mood/apathy,” “attention/memory,” “gastrointestinal,” “sexual dysfunction,” and “miscellaneous” domains in PSP group were significantly higher than those in HC group (P<0.05). The frequency of “mood/apathy,” “attention/memory,” and “sexual dysfunction” domains and the severity of “attention/memory” and “gastrointestinal” domains in PSP group were significantly higher than those in PD group (P<0.05). The “attention/memory” domain in PSP had a significant but weak-to-moderate correlation with age (R=0.387,P=0.046) and onset age (R=0.406,P=0.036).Conclusions. NMS are common in PSP patients. Patients with PSP seem to be subjected to more frequent and severe specific NMS compared to healthy aging subjects and PD patients. Older PSP patients and late-onset patients are likely to be subjected to cognitive decline.


1995 ◽  
Vol 40 (3) ◽  
pp. 187-207 ◽  
Author(s):  
Silvia Sara Canetto ◽  
Patricia L. Kaminski ◽  
Diane M. Felicio

Gender stereotypes of typical and optimal, mentally healthy aging were examined with sixty-year-old and seventy-five-year-old women, men and gender-unspecified older people as target persons. Respondents were young adult individuals ( N = 232) and their older adult relatives/acquaintances ( N = 233). Perceptions of typical aging varied depending on the age of the respondent, the target gender and the target age. Gender stereotypes were more pronounced than age stereotypes: respondents described same-gender targets more similarly than same-age targets. Older women were rated higher on dimensions related to nurturance while older men were rated higher on intellectual competence and autonomy. Perceptions of optimal aging were not found to be affected by the gender of the respondent or target. Views of optimal aging, however, were influenced by respondent and target age. These findings suggest a double standard of aging for typical but not for optimal aging.


Author(s):  
Jiatian Bu ◽  
◽  
Yifan Yu ◽  

The spatial behavior of elderlies is essentially the result of interactions between people and the environment. In order to explore a demand-responsive spatial intervention through new types of data from the perspective of urban planning, this study attempts to identify the differentiated trip features within the aged group, and proceed to gain a further understanding of their daily trip pattern, trip chain, and daytime activity sequence . 76 older residents from a typical public housing neighborhood in Shanghai were asked to carry an Android Phone for 102 consecutive days. By collecting and analyzing the trajectory data, we found that even in a highly consistent social and physical environment, there are still significant differences among the elderlies’ daily activities, mainly existing in the age and gender aspects. The research indicates that elderlies’ daily trip patterns are related to the starting point, effective interval, travel time, and the physical conditions of the individuals.


2015 ◽  
Vol 5 (2) ◽  
pp. 42-47
Author(s):  
Radish Kumar Balasubramanium ◽  
Dhanya Monnappa

ABSTRACT Introduction The anatomical and physiological changes in the phonatory system due to aging have a major impact on voice. Widely researched parameters of voice like fundamental frequency and the perturbation measures have strong correlation with age. However, these measures depend on the location of the exact pitch pulses and it may yield unreliable results in case of a severely aperiodic voice. Also, harmonic measures of voice in healthy aging are scanty in the literature. Aim The present study focused on determining the changes in harmonic-related measures in healthy aging individuals using spectral amplitude measures. Materials and methods The participants were classified into three groups as young, middle-aged, and elderly adults based on their age. All the participants were required to sustain three different types of vowels. Voice samples were analyzed using CSL software to obtain the spectral amplitude measures. Results This showed that there was a decrease in spectral amplitude measures with aging. Discussion Thus, suggesting that the harmonic structure of voice is not affected in healthy aged individuals. Vowel type and gender also influences the harmonic-related measures in the healthy aging population. Conclusion The results of the present study could be used by the voice clinicians while assessing adults with voice disorders. It will also help the clinicians in delineating the age and gender differences in the vocal parameters. How to cite this article Monnappa D, Balasubramanium RK. Estimation of Spectral Amplitude Measures in Healthy Aged Individuals. Int J Phonosurg Laryngol 2015;5(2):42-47.


Women’s Neurology details how to best care for women with neurological disorders. It can be challenging for physicians to stay on top of the latest research about how sex and gender affect the course of specific diseases, medication effects, and best neurological care. The book’s raison d’être is therefore to heighten caregivers’ awareness about the gender differences in neurological care. It spans the neurological issues that occur at different portions of women’s lives, including reproductive health, pregnancy, and issues around healthy aging. The book addresses a range of topics about women’s health and gender-specific neurological care. Topics include issues that are unique to women, as well as those that may affect both men and women, but have a different risk, prevalence, presentation or treatment considerations for women. The book’s format is based on the “What Do I Do Now?” texts, using case examples of common problems and questions that involve women with neurological disease and discussing how to best address the key issues. The aim is to give practical advice for everyday problems clinicians face in caring for women.


2020 ◽  
Vol 52 (9) ◽  
pp. 4165-4184
Author(s):  
David J. Mack ◽  
Sebastian Heinzel ◽  
Andrea Pilotto ◽  
Lena Stetz ◽  
Sandra Lachenmaier ◽  
...  

2014 ◽  
Vol 41 (1) ◽  
pp. 193-202 ◽  
Author(s):  
Noora M. Scheinin ◽  
Kristina Wikman ◽  
Antti Jula ◽  
Markus Perola ◽  
Tero Vahlberg ◽  
...  

2021 ◽  
Author(s):  
Zhou Jiang ◽  
Juan Wang ◽  
Denise Imai ◽  
Timothy Snider ◽  
Ruby Mangalindan ◽  
...  

Pharmaceutical intervention of aging requires targeting multiple pathways, thus there is rationale to test combinations of drugs each targeting different but overlapping processes. In order to determine if combining drugs previously shown to improve lifespan would have greater impact than any individual drug, a diet containing rapamycin at 14 ppm, acarbose at 1000 ppm, and phenylbutyrate at 1000 ppm was fed to 20-month-old C57BL/6 and HET3 4-way cross mice of both sexes for three months. Mice fed the cocktail diet showed a strain and gender-dependent phenotype consistent with healthy aging including decreased body fat and blood glucose, improved cognition, and increased grip strength and walking ability compared to mice fed individual drug or control diets. A cocktail diet containing one-half dosing of each compound was overall less effective than the full dose. The composite age-related lesion score of heart, lungs, liver and kidney was decreased in mice fed the cocktail diet compared to mice fed individual drug or control diets suggesting an interactive advantage of the three drugs. Senescence and inflammatory cytokine levels in kidneys from mice fed the cocktail diet were lower than in kidneys from mice fed control diet, and consistent with low expression levels in kidneys from young untreated mice, suggesting the cocktail diet delayed aging partly by senolytic and anti-inflammatory effects.


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