Effects of liraglutide, a glucagon-like peptide-1 analog, on left ventricular remodeling assessed by cardiac magnetic resonance imaging in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention

2015 ◽  
Vol 31 (8) ◽  
pp. 1239-1246 ◽  
Author(s):  
Tsuyoshi Nozue ◽  
Masayo Yamada ◽  
Tetsuji Tsunoda ◽  
Hiromasa Katoh ◽  
Shimpei Ito ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Myocardial Infarction ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Coronary Intervention ◽  
Left Ventricular ◽  
Resonance Imaging ◽  
Percutaneous Coronary ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1

scholarly journals Effects of Levosimendan Preconditioning on Left Ventricular Remodeling after Myocardial Reperfusion in Acute Myocardial Infarction Patients Receiving Percutaneous Coronary Intervention

2022 ◽  
Vol 25 (1) ◽  
pp. E001-E007
Author(s):  
Shengqin Yu ◽  
Jindong Zhang
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Protective Factor ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Coronary Intervention ◽  
Left Ventricular ◽  
Myocardial Reperfusion ◽  
Observation Group ◽  
Percutaneous Coronary

Objective: Levosimendan is a novel drug often used to treat heart failure. We aimed to explore the effects of levosimendan preconditioning on left ventricular remodeling (LVR) after myocardial reperfusion in acute myocardial infarction (AMI) patients receiving the percutaneous coronary intervention (PCI). Methods: A total of 258 AMI patients treated from January 2018 to September 2020 were randomly divided into control and observation groups. Based on conventional drug therapy, levosimendan was given 30 min before PCI for the observation group, and dobutamine was intravenously injected for the control group. Baseline data, thrombolysis in myocardial infarction (TIMI) blood flow grade, myocardial injury markers, and LVR indices were compared, and the influencing factors for LVR were analyzed. Results: After treatment, various degrees of blood perfusion were found, and the TIMI grade was better than that before treatment in both groups (P < .05). The levels of aspartate aminotransferase, creatine kinase-MB, cardiac troponin T, and brain natriuretic peptide (BNP) declined in both groups, more significantly in the observation group (P < .05). Left ventricular end-systolic diameter, left ventricular end-diastolic diameter and left ventricular end-diastolic volume declined, whereas left ventricular ejection fraction rose in both groups, more significantly in the observation group (P < .05). Age and BNP were risk factors for LVR, whereas levosimendan preconditioning was a protective factor (P < .05). Conclusion: Levosimendan preconditioning can protect cardiac function and promote the recovery of the left ventricular structure. Age and BNP are risk factors for LVR after myocardial reperfusion in AMI patients undergoing PCI, and levosimendan preconditioning is a protective factor.

Serial Magnetic Resonance Imaging of Global and Regional Left Ventricular Remodeling during 1 Year after Acute Myocardial Infarction

Cardiology ◽  
2001 ◽  
Vol 96 (2) ◽  
pp. 106-114 ◽  
Author(s):  
Anne Pauline Schroeder ◽  
Kim Houlind ◽  
Erik Morre Pedersen ◽  
Torsten Toftegaard Nielsen ◽  
Henrik Egeblad
Keyword(s):  
Magnetic Resonance Imaging ◽  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Magnetic Resonance ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Left Ventricular ◽  
Resonance Imaging ◽  
Serial Magnetic Resonance Imaging

Serial cine-magnetic resonance imaging of left ventricular remodeling after myocardial infarction in rats

2001 ◽  
Vol 14 (5) ◽  
pp. 547-555 ◽  
Author(s):  
Matthias Nahrendorf ◽  
Frank Wiesmann ◽  
Karl-Heinz Hiller ◽  
Kai Hu ◽  
Christiane Waller ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Myocardial Infarction ◽  
Magnetic Resonance ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Left Ventricular ◽  
Cine Magnetic Resonance Imaging ◽  
Resonance Imaging
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